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Winners of the Imagining the Brain competition announced - MRC…
https://www2.mrc-lmb.cam.ac.uk/winners-of-the-imagining-the-brain-competition-announced/16 Dec 2013: This article is no longer available from the source website: Cambridge News 16 December 2013.
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Salt chemosensation in worms linked to human deafness - MRC…
https://www2.mrc-lmb.cam.ac.uk/salt-chemosensation-in-worms-linked-to-human-deafness/31 Jan 2013: More generally, the study suggests that TMCs comprise a new family of ion channels that may participate in a range of sensory transduction processes in humans and other animals.
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Watching neurons transmit visual information - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/watching-neurons-transmit-visual-information/21 May 2013: Work in Leon Lagnado’s group in the LMB’s Neurobiology Division is showing how synapses transmit visual signals in the retina of zebrafish. The group
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What’s in a workspace? Brad Amos and his basement - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/whats-in-a-workspace-brad-amos-and-his-basement/9 Jul 2013: Professor Brad Amos has spent much of his career designing and developing microscopes that are now used in laboratories around the world... He showed
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Take part in real research with ‘WormWatch Lab’ - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/take-part-in-real-research-with-wormwatch-lab/3 Jul 2013: Anyone with an interest in science can take part in an egg-themed online video game, organised to help advance the LMB’s research into the circuitry of
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Ari Helenius to deliver 2013 Max Perutz lecture - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/ari-helenius-to-deliver-2013-max-perutz-lecture/23 Apr 2013: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures
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100 years from now: Jason Chin on synthetic biology - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/100-years-from-now-jason-chin-on-synthetic-biology/21 Jan 2013: LMB's Jason Chin discusses synthetic biology, and where research will take us in the next 100 years, for the Centenary edition of MRC Network, page 26
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Discovery of the genetic basis of a rare immune disease - MRC…
https://www2.mrc-lmb.cam.ac.uk/discovery-of-the-genetic-basis-of-a-rare-immune-disease/22 Oct 2013: For all of these patients, the use of PI3K delta inhibitors offers a potential and exciting new avenue of treatment aimed at normalising the function of immune cells and thereby prevent
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Smart neurons: single dendrites can perform computations - MRC…
https://www2.mrc-lmb.cam.ac.uk/smart-neurons-single-dendrites-can-perform-computations/1 Nov 2013: A study, published in the journal Nature and carried out by researchers based at the Wolfson Institute for Biomedical Research at UCL, LMB's Tiago Branco
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> Home > Software > REFMAC5 > Dictionary Dictionary ...
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/refmac/Dictionary/dictionary.html1 Jul 2013: It is better JLigand to generate new entries and links. It is an external resource at the moment. ... There are number of very good resources to generate new entries. -
refmac 5.8 series
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/refmac/features.html14 Aug 2013: >New features. Note: New features are listed in reverse chronoligical order not in order of their importance. ... Version. Feature id. Feature description. Requested by. 5.8.0023. Scaling. New function for scaling has been added (by default this function -
> Home > Software > REFMAC5 > Dictionary Dictionary ...
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/refmac/Dictionary/bug_fixes.html1 Jul 2013: In new pdb edition it their names are H5' and H5''. ... This version is compliant with new pdb. Many users. 5.41. EPE. -
MRC Millennium medal recognises LMB’s exceptional research - MRC…
https://www2.mrc-lmb.cam.ac.uk/mrc-millennium-medal-recognises-lmbs-exceptional-research/28 Feb 2013: Monoclonal antibodies account for a third of all new treatments including therapeutic products for breast cancer, leukaemia, asthma, arthritis, psoriasis and transplant rejection.
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World premiere for music inspired by human genomes - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/world-premiere-for-music-inspired-by-human-genomes/10 Apr 2013: The world premiere of a piece of music inspired by human genetic variation will be the centrepiece of the 3rd biennial Royal Greenwich String Quartet
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Huzzah To The Double Helix! It’s International DNA Day - MRC…
https://www2.mrc-lmb.cam.ac.uk/huzzah-to-the-double-helix-its-international-dna-day/25 Apr 2013: To celebrate the DNA 60 anniversary, several Australian scientists have released statements about the wonders of DNA, including LMB alumnus Professor
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LMB Innovations included in Great British Innovation Vote - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmb-innovations-included-in-great-british-innovation-vote/15 Mar 2013: To celebrate National Science & Engineering Week a public vote for the most important innovation in science and technology is taking place - and
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TRIM21 senses infection and triggers immune response inside cells -…
https://www2.mrc-lmb.cam.ac.uk/trim21-senses-infection-and-triggers-immune-response-inside-cells/4 Mar 2013: New research, led by Leo James and Will McEwan from the LMB’s PNAC Division, has uncovered a previously unrecognised mechanism of intracellular pathogen detection which may provide a deeper understanding ... The new findings, published in Nature
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LMB's Felix Randow in discussion with Annalisa M. VanHook - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmbs-felix-randow-in-discussion-with-annalisa-m-vanhook/18 Feb 2013: LMB's Felix Randow in discussion with Annalisa M. VanHook from the journal Science about the process of autophagy. More...
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Virus Wars – thousands visit LMB stand at the Royal Society - MRC…
https://www2.mrc-lmb.cam.ac.uk/virus-wars-thousands-visit-lmb-stand-at-the-royal-society/10 Jul 2013: Published on. 10 July, 2013. Scientists from Leo James’ group, from the LMB’s PNAC Division, showed their new ‘Virus Wars’ exhibit at this year’s Royal Society Summer Science Exhibition –
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Marc Torrent receives 2013 ICAAC Young Investigator Award - MRC…
https://www2.mrc-lmb.cam.ac.uk/marc-torrent-receives-2013-icaac-young-investigator-award/26 Jun 2013: Dr Marc Torrent from the LMB's Structural Studies Division has been honoured as a recipient of a 2013 ICAAC Young Investigator Award for his work to
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The smell of food ‘wakes up’ the zebrafish visual system - MRC…
https://www2.mrc-lmb.cam.ac.uk/the-smell-of-food-wakes-up-the-zebrafish-visual-system/11 Jul 2013: 11 July, 2013. New research from Leon Lagnado’s group in the LMB’s Neurobiology Division shows how food-related smells ‘re-tune’ zebrafish vision by making the retina more sensitive
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News - Cambs 24
https://www2.mrc-lmb.cam.ac.uk/archive/articles/Road_named_after_legendary_scientist.pdf1 Feb 2013: THE road leading to a new laboratory will be named after renowned scientist Dr Francis Crick. ... Because this road leads to the new laboratory, we wanted someone really prestigious, and what better choicethan Francis,” he added. -
Tribute to Fred Sanger, including interview with John Walker - MRC…
https://www2.mrc-lmb.cam.ac.uk/tribute-to-fred-sanger-including-interview-with-john-walker/21 Nov 2013: The BBC looks at the life and work of Fred Sanger, including an interview with former LMB colleague, John Walker More…
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Understanding the mechanism of the nucleocytoplasmic transport cycle…
https://www2.mrc-lmb.cam.ac.uk/understanding-the-mechanism-of-the-nucleocytoplasmic-transport-cycle/29 Apr 2013: New research, from a team of scientists in the LMB’s Structural Studies Division and the Texas A&M Health Science Center, illustrates the molecular mechanism behind a fundamental cellular process. ... The research, published in PNAS, provides new
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LMB Scientists Honoured by the UK’s Biochemical Society - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmb-scientists-honoured-by-the-uks-biochemical-society/15 Mar 2013: LMB scientists, M. Madan Babu, Harvey McMahon, Melina Schuh and John Burke, have all been honoured with awards from the Biochemical Society, the UK’s
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A Glimpse Inside the Control Centers of Cell Communication - MRC…
https://www2.mrc-lmb.cam.ac.uk/a-glimpse-inside-the-control-centers-of-cell-communication/18 Feb 2013: Scientists from the LMB’s Structural Studies Division, led by M. Madan Babu in collaboration with Chris Tate (LMB) and researchers from the Paul Scherrer
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Monoclonal antibodies; from their debut to blockbuster status - MRC…
https://www2.mrc-lmb.cam.ac.uk/monoclonal-antibodies-from-their-debut-to-blockbuster-status/15 Aug 2013: They’re found in home-testing kits for pregnancy, hospital tests for MRSA, and in six out of ten of the best-selling drugs today. But monoclonal
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https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/screenshots/new-display-manager-window-page.html12 Jul 2013: -
2013 César Milstein Lecture to be given by Scott Emr - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/2013-milstein-lecture-to-be-given-by-scott-emr/20 Sep 2013: Professor Scott Emr will give the 2013 Milstein Lecture on Thursday 26 September at 4.15pm in the LMB’s Max Perutz Lecture Theatre. The lecture, entitled
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Uncovering molecular signatures of G-protein-coupled receptors - MRC…
https://www2.mrc-lmb.cam.ac.uk/uncovering-molecular-signatures-of-g-protein-coupled-receptors/14 Feb 2013: Recent advances in GPCR biology have led to the determination of new structures of several GPCRs in quick succession and this work reveals new, and critically important details about the similarities
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Understanding timekeeping in an intertidal marine crustacean - MRC…
https://www2.mrc-lmb.cam.ac.uk/understanding-timekeeping-in-an-intertidal-marine-crustacean/27 Sep 2013: The molecular mechanism behind this tidal clock is still a mystery but the finding offers scope for new discoveries of how genes control biologically critical behaviour.
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2013 John Kendrew Lecture to be given by Joan Steitz - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/john-kendrew-lecture-2013-to-be-given-by-joan-steitz/25 Oct 2013: Joan Steitz will give the John Kendrew Lecture 2013 on Friday 1st November at 4.15pm in the LMB’s Max Perutz Lecture Theatre. The title of the lecture is
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Botox jab could ease arthritis and cancer without side effects - MRC…
https://www2.mrc-lmb.cam.ac.uk/botox-jab-could-ease-arthritis-and-cancer-without-side-effects/1 Nov 2013: Sheffield University researcher Professor Bazbek Davletov took the pain-relieving part of Botox and 'stapled' it to a friendly part of a similar poison
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Michael Neuberger elected a Foreign Associate of the US National…
https://www2.mrc-lmb.cam.ac.uk/michael-neuberger-elected-a-foreign-associate-of-the-us-national-academy-of-sciences/2 May 2013: Dr Michael Neuberger, group leader in the LMB’s Protein and Nucleic Acid Chemistry, has been elected as a Foreign Associate of the US National Academy of
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KJ Patel receives Fanconi Anemia Research Fund Award of Merit - MRC…
https://www2.mrc-lmb.cam.ac.uk/kj-patel-receives-fanconi-anemia-research-fund-award-of-merit/18 Dec 2013: KJ Patel, from the LMB’s PNAC Division, has been awarded the Award of Merit for his ‘revolutionary work on aldehyde toxicity in Fanconi anemia
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Exploiting the power of evolution to create designer proteins - MRC…
https://www2.mrc-lmb.cam.ac.uk/exploiting-the-power-of-evolution-to-create-designer-proteins/15 Nov 2013: Nick’s group have shown that the new ‘ligand trap’ is active in cell culture model systems and are currently testing it in a range of other models. ... The molecule identified in this work is a potentially important therapeutic which could lead to
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Ribosome structure determined to near-atomic resolution by cryo-EM -…
https://www2.mrc-lmb.cam.ac.uk/ribosome-structure-determined-to-near-atomic-resolution-by-cryo-em/6 Feb 2013: Two factors were crucial to this success. Firstly, they recorded images with much less noise on a new type of direct-electron detector, which was co-developed with the LMB. ... Secondly, because these new cameras are also very fast, they allowed the
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Drug developed in Cambridge approved for treatment of multiple…
https://www2.mrc-lmb.cam.ac.uk/drug-developed-in-cambridge-approved-for-treatment-of-multiple-sclerosis/20 Sep 2013: Approval concludes nearly 40-year epic journey from fundamental research, begun at LMB, to discovery of an effective treatment for active relapsing
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MRC Laboratory of Molecular Biology welcomes Astra Zeneca to…
https://www2.mrc-lmb.cam.ac.uk/mrc-laboratory-of-molecular-biology-welcomes-astra-zeneca-to-cambridge-biomedical-campus/18 Jun 2013: the way industry collaborates with academia and government to share knowledge and discover and develop new drugs. ... Alongside this, the LMB collaborates with industry, both through sharing its talent and ideas with existing companies and by the
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Vesicles modulate an actin network for asymmetric spindle positioning …
https://www2.mrc-lmb.cam.ac.uk/vesicles-modulate-an-actin-network-for-asymmetric-spindle-positioning-in-oocytes/22 Jul 2013: Published on. 22 July, 2013. Work carried out by Melina Schuh’s group in the LMB’s Cell Biology Division has provided new insights into how the spindle is asymmetrically positioned
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... the Queen hops on a single decker as she tours Cambridge…
https://www2.mrc-lmb.cam.ac.uk/the-queen-hops-on-a-single-decker-as-she-tours-cambridge-nobel-prize-factory/28 May 2013: The mysteries of conception were explained to the Queen today as she toured a world-leading research institute dubbed the "Nobel Prize factory". More...
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A synthetic biology revolution | MRC Annual Review 2012-13
https://www2.mrc-lmb.cam.ac.uk/archive/articles/A_synthetic_biology_revolution.pdf1 Nov 2013: New resource will collect and catalogue stem cells9. New centres put health records at the heart of UK medical research10. ... New research collaborations with China11. Public-private imaging centre to speed drug development12. -
Novel technology useful for development of gene and drug therapies…
https://www2.mrc-lmb.cam.ac.uk/novel-technology-useful-for-development-of-gene-and-drug-therapies-licensed-to-local-company/10 Sep 2013: of new therapeutics. ... This new technology enhances the speed of the early stage drug screening process, and helps those without the necessary chemistry expertise to more rapidly prepare and test a much greater number
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Frederick Sanger: Nobel prizewinning biochemist whose insulin and DNA …
https://www2.mrc-lmb.cam.ac.uk/frederick-sanger-nobel-prizewinning-biochemist-whose-insulin-and-dna-work-transformed-genetics/21 Nov 2013: The biochemist, Fred Sanger, a former Head of the LMB's PNAC Division, has died aged 95. He had the rare distinction of winning the Nobel Prize twice, in
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FORMA therapeutics and Cancer Research Technology to discover cancer…
https://www2.mrc-lmb.cam.ac.uk/forma-therapeutics-and-cancer-research-technology-to-discover-cancer-drugs-targeting-deubiquitinating-enzymes-dubs/10 Jul 2013: LMB's David Komander is part of collaborative consortium including FORMA Therapeutics and Cancer Research Technology, aiming to discover cancer drugs
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A new line of research in the fight against Alzheimer's disease…
https://www2.mrc-lmb.cam.ac.uk/archive/articles/A_new_line%20of_research_in_the_fight_against_Alzheimer's.pdf1 Feb 2013: A new line of research in the fight against Alzheimer's diseaseand dementiaJanuary 26 2010. ... Top of page. A new line of research in the fight against Alzheimer's disease. -
Insights into spliceosomal activation and molecular pathology of…
https://www2.mrc-lmb.cam.ac.uk/insights-into-spliceosomal-activation-and-molecular-pathology-of-retinitis-pigmentosa-eye-disease/31 May 2013: Work published in the journal Structure by Kiyoshi Nagai’s group in the LMB’s Structural Studies Division, has provided further detailed information on
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Identifying behavioural functions for genes has produced a key…
https://www2.mrc-lmb.cam.ac.uk/identifying-behavioural-functions-for-genes-has-produced-a-key-resource-for-neuroscience-research/15 Jul 2013: While fully sequenced genomes are available for many important experimental organisms, a major challenge has been to identify the functions of the genes
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In this activity, students use a template to make ...
https://www2.mrc-lmb.cam.ac.uk/viruswars/images/VirusWars_TeachersNotes.pdf27 Jun 2013: Describe the different shapes of viruses and the process viruses use to infect a host cell, replicate, and infect new viruses. ... Ã Understanding how TRIM21 and antibodies work may help scientists devise new therapies for virus infection. -
pnas201313978 4601..4610
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/pnas2013duman.pdf23 Dec 2013: The G109K substitution has a dramatic ef-fect, because in the new crystals the protein filaments are absent,but dimers are still present (Fig. ... Construction of Plasmids for Protein Purification. pMal-C2X (New EnglandBiolabs) was used to clone and
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