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  2. 53091 361..366

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/McMahon01020.pdf
    3 Dec 2004: Theformation of a new vesicle is thought to be driven by both thepolymerization of the coat protein clathrin into a cage-like structureand the selection/modification of membrane lipids5,6. ... solved in the absence of a lipid head group14 (Fig. 2a,
  3. se289900215p

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/strucrev.pdf
    6 Jul 1999: icle membrane or cellular responses to envi-ronmental stimuli. The developments seenover the past couple of years will continue;new insights and structures will be publishedsoon. ... The challenge for the new century willbe to understand how these
  4. Cryo-EM reconstruction of AlfA from Bacillus subtilis reveals the…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/AlfA2018.pdf
    20 Mar 2018: The antiparallel orientation of the. filaments is necessary to ensure that when new protomers areadded to the spindle, it grows in opposite directions and pushes theplasmid copies apart (23). ... FASEB J 9:167–174.36. Krissinel E, Henrick K (2004)
  5. 2077 741..748

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/21_Lingappa_VR_BioEssays_2002.pdf
    5 Jul 2002: Furthermore, new. Table 1. Organizing principles for the levels of complexity in protein folding. ... A new varia-. tion on the translocation of proteins occurs during the early biogenesis of.
  6. Model-Building with Coot Paul EmsleyUniversity of Oxford June 2011 ...

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/aca-2012-low-resolution-scripting-ligands-and-bumps.pdf
    28 Jul 2012: Overview of Presentation: New algorithms and features Tips on Usage Focus on:. ... Hydrogen tunnelling. Alpha Helix Placement Scenario: Looking at a new map, not built with.
  7. The life of proteins: the good, the mostly good and the ugly

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/68_Morimoto_RI_NSMB_2011.pdf
    7 Jan 2011: Several new concepts and methods are bringing nascent-chain biology to the forefront of the field. ... Nascency and nascent-chain biologyReplenishment and renewal of the ‘protein community’ of cellular proteins requires new proteins to be synthesized.
  8. st7a11.qxd

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MukB%20Structure%201999.pdf
    10 Sep 1999: Yale University Press, New Haven, CT. 31. Engh, R.A. & Huber, R. ... Columbia University, New York. Research Article MukB crystal structure van den Ent et al.
  9. Cover MRC Case Studies FAW09

    https://www2.mrc-lmb.cam.ac.uk/archive/articles/Reviewing_translation_at_the_MRC.pdf
    15 Apr 2015: MRC science needs to be effectively translated into powerful new therapies, diagnostics, devices, and research tools. ... then for investigating other potential protein modifications. The technology will help produce new protein reagents that.
  10. mk069902063p

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Fitting.MBC.pdf
    26 May 1999: We present a new map showing dimeric kinesin bound to microtubules in the presenceof ADP that was obtained by electron cryomicroscopy and image reconstruction. ... Interactions with TubulinMonomeric kinesin is represented in Figure 9 as aspace-filling
  11. The Jour nal o f Cel l Bio logy ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/epsinR.pdf
    9 Jan 2003: synergin and useto predict that an uncharacterized EF-hand–containingprotein will be a new gamma binding partner. ... We have proposed that on binding to membranes,this new helix buries itself between the lipid headgroups,pushing the lipids apart and
  12. S413_6a 39..44

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MreB%20Nature.pdf
    30 Aug 2001: 35. BruÈ nger, A. T. et al. Crystallography & NMR system: a new software suite for macromolecular.
  13. se289900215p

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/research/strucrev.pdf
    6 Jul 1999: icle membrane or cellular responses to envi-ronmental stimuli. The developments seenover the past couple of years will continue;new insights and structures will be publishedsoon. ... The challenge for the new century willbe to understand how these
  14. se060101051p

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/epsin/EM/ford.pdf
    3 Dec 2004: 17,4943 (1998). 35. A. G. W. Leslie, in Joint CCP4 and ESF-EACMB News-letter on Protein Crystallography No.
  15. DOI: 10.1126/science.1184429 , 1638 (2010); 327Science et al.Simon…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20339072.pdf
    2 Aug 2010: The title. CopyrightAmerican Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005. ... This can becrucial in the design of new generations of Vps34inhibitors with improved specificity, solubility,and cellular
  16. doi:10.1016/j.cub.2004.07.058

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15296756.pdf
    6 Oct 2004: 2001). Rap1 signal-ling: adhering to new models. Nat. Rev. Mol. Cell Biol.
  17. Activation of Xer-recombination at dif: structural basis of the…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/srep33357.pdf
    30 Sep 2016: New Biol 3, 799–811 (1991). 7. Carnoy, C. & Roten, C. ... J. & Donachie, W. D. A new Escherichia coli cell division gene, ftsK.
  18. Changes in Postural Syntax Characterize Sensory Modulation and…

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-5.pdf
    14 Aug 2015: New imaging technology has made it possible to record neural activity from the majority ofC. ... 2. Lehner PN. Handbook of ethological methods. 2nd ed. Cambridge ; New York: Cambridge UniversityPress; 1996.
  19. No Job Name

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MreC%20MM%202006.pdf
    7 Dec 2006: 2005) A high-throughput structuralbiology/proteomics beamline at the SRS on a new multi-pole wiggler. ... New York, NY:Academic Press, pp. 472–494. Defeu Soufo, H.J., and Graumann, P.L.
  20. Phil. Trans. Roy. Soc. Lond. B. 261, 95-104 (1971) ...

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/ptrs71.pdf
    26 Nov 2012: 1964 Fundamentals riftransmission electron microscopy. New York: Interscience. Heidenreich, R. D. &
  21. TBS may template.qxd

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/epsin/EM/mcmahon.pdf
    3 May 2002: J. Biol. Chem. 275, 38597–38604. 33 Darrouzet, E. et al. (2001) Large scale domainmovement in cytochrome bc1: a new device forelectron transfer in proteins.
  22. mbar-v2

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/model-building-and-refinement-v2.pdf
    31 Aug 2018: proceed. 2.2.3.The new waters have been added to chain D, and it is important to inspect them and make sure that they have all been added in appropriate
  23. Cryo‐EM structure of the full‐length Lon protease from Thermus…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf
    14 Nov 2021: The new model containing a coiled-coil. a-helix describes map 2 well. ... Hagen WJH, Lindahl E and Scheres SHW (2018) New. tools for automated high-resolution cryo-EM structure.
  24. doi:10.1016/j.pbiomolbio.2004.07.009

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/stock2005robot.pdf
    19 Jan 2005: authors. Thesedevelopments along with advances in structure determination techniques (mainly the use ofsynchrotrons, area detectors and crystal freezing) led to an enormous increase in new proteinstructures: in 1990, about 500 structures
  25. ANALYSIS Integrating molecular and network biologyto decode…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Schmid_Nature2007.pdf
    22 Aug 2007: c, Changing hubs: clathrin is recruited andpolymerization stabilizes the forming vesicle, displacing the AP2recruitment hub and becoming the new organizing hub. ... Clustered hubs’ are a new sub-type of hubs not previously described (Supplementary
  26. 201010176 1..6

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2010-Aylett-TubZ.pdf
    21 Oct 2010: The identificationof quadruple as well as double filaments posed a new question,however: Which filament is present in cells? ... Both formed filaments similar to those of native TubZ. We then reconstructed the new filaments in three dimensionsto reveal
  27. x16412u141

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MaoAP180-2001.pdf
    17 Mar 2003: cells. After induction with IPTG for 4 hr at 378C, cells were a new member of the AP-3 clathrin assembly protein family. ... Nature 347,N.S., et al. (1998). Crystallography and NMR system: a new software402–406.suite for macromolecular structure
  28. Dynamin-dependent and dynamin-independentprocesses contribute to the…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Graham02.pdf
    29 Apr 2002: a new mean half-width.
  29. doi:10.1016/j.jmb.2007.08.056

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Oliva_FtsZ_JMB_2007.pdf
    11 Oct 2007: We propose a new model in whichlateral interactions help determine the curvature of protofilaments. ... Similarly, our new pair of AaFtsZ:GDPand AaFtsZ:8-morpholino-GTP show even smallerdifferences (rmsd 0.2 Å).
  30. Bb9e55.qxd

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Vallis_McMahon1999.pdf
    21 Mar 2003: of dynamin at a single site that defines a new SH3binding consensus sequence.
  31. Tutorial 4: Statistical Theory;Why is the Gaussian Distribution so ...

    https://www2.mrc-lmb.cam.ac.uk/download/tutorial-4-statistical-theory/?wpdmdl=18816&refresh=669fceb1b90451721749169
    20 Mar 2014: 7. Use a ‘for loop’ to iteratively recreate a new random Bin(100, 0.4) sample of100 observations and overplot the corresponding empirical density functionsonto the plot of the Normal density
  32. Calcium-mediated Evidence from the Changes in Gap Junction Low ...

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jcb83.pdf
    1 Nov 2012: St. Louis, MO); sodium deoxycholate from Calbiochem-Behring Corp. (La Jolla, CA); and HLlabeled sodium deoxycholate (4 Ci/mmol) from New England Nuclear (Boston, MA).
  33. DOI: 10.1126/science.1256917, 963 (2014);346 Science et al.Thomas G.…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Science-2014-Gligoris-963-7.pdf
    21 Nov 2014: The title. CopyrightAmerican Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005. ... Cross-linking cohesin containing cysteinesat all three interfaces generated a new formform (Ci) whose electrophoretic mobility
  34. se060101047p

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Itoh%20et%20al.pdf
    23 Nov 2004: X-ray Crystallography and NMR (Yale Univ. Press,New Haven, CT, 1993). 24.
  35. pone.0107211 1..10

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/leoa2014.pdf
    3 Sep 2014: LeoA, B and C from Enterotoxigenic Escherichia coli(ETEC) Are Bacterial DynaminsKatharine A. Michie1.¤a, Anders Boysen2., Harry H. Low1.¤b, Jakob Møller-Jensen2, Jan Löwe1. 1 MRC Laboratory of Molecular Biology, Structural Studies Division,
  36. Biol. Chem., Vol. 381, pp. 993 – 999, September/October ...

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/BiolChem%20Helical%20Tubes.pdf
    13 Sep 2000: Biol. Chem., Vol. 381, pp. 993 – 999, September/October 2000 Copyright by Walter de Gruyter Berlin New York.
  37. Bacterial actin MreB assembles in complex with cell shape protein RodZ

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embo2010RodZMreB.pdf
    17 Feb 2010: References. Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ,Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Terwilliger TC(2002) PHENIX: building new software for automated crystal-lographic ... Mol Microbiol 51:1321–1332. Gerdes K (2009)
  38. DOI: 10.1126/science.1135394 , 239 (2007); 317Science et al.Nabil…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17626883.pdf
    8 Dec 2007: The title. CopyrightAmerican Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005.
  39. Contrasting Membrane Interaction Mechanisms of AP180N-terminal…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Stahelin_cho2003.pdf
    16 Jul 2003: the Department ofMicrobiology and Immunology, Weill Medical College of Cornell University, New York, New York 10021, andthe Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of ... Karol Bruzik.Phospholipid
  40. MR_LMB

    https://www2.mrc-lmb.cam.ac.uk/download/molecular-replacement/?wpdmdl=18799&refresh=669fcead5ddfc1721749165
    11 Jun 2013: Molecular replacement. New structures from old. The Phase Problem. amplitude. phase.
  41. PII: 0896-6273(89)90235-3

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/neuron89.pdf
    11 Sep 2003: New channel proteins are being discovered and characterized, Superfamilies of voltage- and ligand-gated channels are being identified and ex- tended. ... without the energetically unfavored pro- cesses of creating substantial new surfaces or invoking
  42. Structure of the hexagonal surface layer on Caulobacter crescentus…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/s-layer-nmicrobiol201759.pdf
    6 Apr 2017: 3), requiring RsaA to adoptslightly different conformations. Furthermore, gaps in the latticewill be needed for insertion of new RsaA molecules on growingcells. ... The new culture was grown at 30 C for2–3 days. The culture was imaged using a
  43. doi:10.1128/mBio.00800-13. 4(6): .mBio. Midcell DNA Translocase FtsK…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mbio2013bisicchia.pdf
    23 Dec 2013: CONTENT ALERTS. more>>article), Receive: RSS Feeds, eTOCs, free email alerts (when new articles cite this.
  44. Supplementary Text & Figs

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Schmid_Nature2007Sup.pdf
    22 Aug 2007: be appropriately interpreted. Part 3: Clustered-hubs. Clustered-hubs are a new subtype of hubs not previously described. ... new subtype of hubs that we find in CME. These can be composed of proteins with.
  45. Bacterial actin: architecture of the ParMRC plasmidDNA partitioning…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/ParMRC%20Salje%202008%20EMBO.pdf
    4 Aug 2008: ParM filaments while allowing entry of new ATP-bound. monomers. We propose a processive mechanism by which. ... The binding of a new subunit. induces ATP hydrolysis in the previous subunit of the proto-.
  46. Journal of Visualized Experiments www.jove.com Copyright © 2018…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/JOVE2018.pdf
    19 Apr 2018: protein droplets (each row now requires 8 new microsyringesto avoid cross-contamination).
  47. MeganPalm

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/MeganPalm.pdf
    3 Dec 2005: to find out new search regions to detect all the eggs attached to the worm body. ... previously used for the egg detection test and 20 new normal wild type videos.
  48. Many bacterial plasmids are maintained at low copy number ...

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/nrmicro2425.pdf
    14 Sep 2010: Filaments stabilized in this way continue to polymerize with the addition of new ParM subunits at both ParR–parC-capped ends, although the actual rate of elongation of an individual
  49. ©20 10 N atur e A mer ica, Inc. ...

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20081827.pdf
    2 Aug 2010: We devised a new expression and purification strategy by introducing a TEV protease. ... All propeller-shaped inhibitors create a new specificity pocket not present in the apo form of the enzyme.
  50. Activation of GCN2 by the ribosomal P-stalk

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/PNAS_2019.pdf
    7 Mar 2019: New insight into a possible functional link be-tween GCN2 and ribosomes came from a recent analysis of micelacking both a specific neuronal tRNA (tRNAArgUCU) and theputative ribosome recycling factor GTPBP2
  51. Filament structure and subcellular organization of the bacterial…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Liu_PNAS_crescentin_2024.pdf
    28 Apr 2024: contributed new reagents/analytic tools; Y.L. and J.L. analyzed data; and Y.L.

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