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241 - 260 of 318 search results for news |u:www.ubs.admin.cam.ac.uk
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  2. PPL number: | Granted: 25 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_pathobiology_and_therapeutic_opportunities_of_ubiquitin_ligases_nts_redacted.pdf
    13 Sep 2021: We will perform pilot studies testing any new therapies in very small groups of normal mice. ... These new therapies will have already been tested in isolated cells in the laboratory.
  3. PPL number: | Granted: 13 Jan 20 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/molecular_and_genetic_regulation_of_glial_development_and_function_nts_redacted.pdf
    19 Aug 2021: We hope this will help find new ways to treat or prevent brain disease. ... However, when we develop new techniques, we carefully consider the literature and seek expert advice before starting.
  4. PPL number: | Granted: 23 Oct 20 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/evaluation_of_novel_strategies_for_bone_repair_nts_redacted.pdf
    19 Aug 2021: These papers will describe the development of a new type of bone repair material. ... the structure may be compromised, while if it too slow it may adversely affect new bone formation.
  5. PPL number: | Granted: 18 Nov 20 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/papillomavirus_transmission_infection_and_lesion_formation_nts_redacted.pdf
    19 Aug 2021: basal skin layer, the productive life cycle is triggered and new viruses are produced; iv) PV is shed inside dead cells from the surface of. ... new insight into PV transmission mechanisms, and the development of anti-papillomavirus agents/treatments and
  6. PPL number: | Granted: 17 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/roles_for_genomic_instability_in_cancer_and_ageing_redacted.pdf
    18 Jun 2021: Page 3 of 10. New genes of interest will be identified and described. ... Thus, finding new biomarkers improves our ability to both detect and treat cancer.
  7. PPL number: | Granted: 28 Jul 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/developing_anti-malarial_transmission_blocking_interventions_nts_redacted.pdf
    13 Sep 2021: What's the aim of this project? This project aims to discover and develop new ways to treat or prevent malaria transmission and disease. ... As such, the development of new anti-malaria blocking strategies is a major objective.
  8. Mouse developmental genetics to study neurodevelopment and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mouse_developmental_genetics_to_study_neurodevelopment_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: suffer from traumatic brain injuries and 14 million new incidents of stroke globally, each year. ... may require the generation of new transgenic animals, therefore reducing the number of animals needed to fulfil the objectives we set up in this license.
  9. Ischaemia Reperfusion Injury and Organ Transplantation (non-technical …

    https://www.ubs.admin.cam.ac.uk/system/files/public/ischaemia_reperfusion_injury_and_organ_transplantation_non-technical_summary_redacted.pdf
    30 Apr 2024: The treatments that are validated in the project may include new intellectual property. ... Altogether, these will generate a blueprint for clinical studies, which will bring successful new treatments to patients.
  10. PPL number: | Granted: 25 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/circuit_mechanisms_of_learning_and_memory_in_the_mammalian_brain_redacted.pdf
    18 Jun 2021: The new insights gained could lead to new strategies for treating such disorders, including learning disabilities and Alzheimer's disease. ... Moreover, our institution's web pages provide regular updates on new developments in the 3Rs.
  11. Neurobehavioural Mechanisms Underlying Mood, Anxiety and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_anxiety_and_stress-related_mental_health_disorders_non_redacted.pdf
    30 Apr 2024: Ultimately, the intention is that this research will lead to new treatments being developed for mood, anxiety and stress-related mental health disorders. ... benefit people living with mental health disorders through the development of new treatments.
  12. Platelets as a therapeutic tool

    https://www.ubs.admin.cam.ac.uk/system/files/public/platelets_as_a_therapeutic_tool_non-technical_summary_redacted.pdf
    30 Apr 2024: If the pilot experiment raises unexpected new questions, a subsequent pilot experiment will be performed. ... We will routinely check the NC3R's resource library and keep abreast with, and implement where appropriate, any new advances in refinement,
  13. PPL number: | Granted: 05 May 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/safety_efficacy_and_immunogenicity_of_regenerative_cellular_therapies_redacted.pdf
    18 Jun 2021: This network will be utilised to maximise the dissemination of the new knowledge gained through this project. ... 3) By generating large quantities of human cells, where appropriate, we can continue to perform new studies using the same human cells.
  14. The development of in vivo expressed biologics as a platform for…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_in_vivo_expressed_biologics_as_a_platform_for_novel_therapeutic_agents_non-techn_redacted.pdf
    30 Apr 2024: Therefore there is a clear need to pioneer new medical treatments and technologies to address this increasing disease burden. ... This will inform specific drug projects that are aiming to produce new medicines for patients.
  15. PPL number: | Granted: 12 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/promoting_proliferation_in_non-regenerative_tissues_redacted.pdf
    18 Jun 2021: The work will;. 1. Provide new insights into the mechanisms required for regeneration. ... Thus, animal experiments are essential to understand regulatory mechanisms and to design and test potential new therapies.
  16. PPL number: | Granted: 09 Sep 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_for_the_treatment_of_cancer_nts_redacted.pdf
    13 Sep 2021: The research will aid in the development of new bacterial therapies to treat cancer. ... We continuously consider their use and development in light of new experimental data.
  17. Control of equine herpesviruses in the horse

    https://www.ubs.admin.cam.ac.uk/system/files/public/control_of_equine_herpesviruses_in_the_horse._non-technical_summary_redacted.pdf
    29 Apr 2024: This project will develop and test the safety and effectiveness of new vaccines against EHV induced disease. ... Comprehensive details are provided for the new owner and advice given in any areas required.
  18. PPL number: | Granted: 30 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_mechanisms_involved_in_genome_regulation_nts_redacted.pdf
    13 Sep 2021: This second part will provide new hypotheses and research avenues for future research projects about mitochondrial and neurodegenerative diseases. ... Data generated from this project will form the basis for new funding applications, and may eventually
  19. The diversity of glia in health, development and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_diversity_of_glia_in_health_development_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: We hope that this will help us develop new treatments for diseases that are caused by problems with myelin. ... Other enrichments like tunnels, climbing structures, and new objects can be added to encourage natural behavior.
  20. PPL number: | Granted: 22 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_germ_free_and_gnotobiotic_animals_service_licence_nts_redacted.pdf
    13 Sep 2021: In order to produce new mouse colonies a minority of germ-free mice will be given mammalian gut bacteria orally to produce gnotobiotic mice with a known gut flora (bacteria).
  21. Development of novel therapeutics for pain (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_novel_therapeutics_for_pain_non-technical_summary_redacted.pdf
    30 Apr 2024: relevant disease animal models to give us an extra layer of confidence in developing these new medications. ... In all new studies undertaken, the level of insult will be assessed before conducting further studies.

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