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7 Mar 2023: Project Licences (a) New licence: The committee discussed the following:. • The removal of the by name from the Non-Technical Summary. • ... c) New Licence: The committee discussed the following:. • Further justification required in regards to

7 Dec 2022: Further consideration given to new lines and expected adverse effects to ensure the licence is not.

7 Dec 2022: receive prior to taking over the Licence. • The recommendation that if there is any intention to hold animals on the Licence before the new.

20 Aug 2021: Longer-term benefits will be opportunities for making new treatments for controlling fertility in humans.

19 Aug 2021: Understanding the mechanisms that control killing by these cells will improve the design of new immunotherapies. ... We will provide new information on pathways that are required by killer cells of the immune system.

29 Apr 2024: What's the aim of this project? The overall aim of the research is to develop new and improved vaccines. ... New vaccines need to be safe, well tolerated, effective and offer broad coverage against many pathogens.

13 Sep 2021: Longer-term benefits will be opportunities for making new treatments for controlling fertility in humans.

18 Aug 2015: 16. Slide 16: Why replace animals? - Scientific advantages: New technology can be exploited. ... The development of new technologies opens up opportunities for expanding or improvingresearch in a variety of ways.

30 Apr 2024: Our plan is to publish research papers with new information on which human diseases involve programmed axon death and which specific people are most at risk. ... As we have shown, when a new 3Rs method becomes available (e.g., hiPSC-derived neurons), we

19 Aug 2021: It also allows for the initial testing of new treatment compounds to assess their compatibility. ... This enables the brain to make new circuits to bypass the damaged neurons.

13 Sep 2021: The work will identify exactly how aneurysms develop and new treatments to prevent this. ... culture. Some aspects of disease including assessment of new treatments still require animal studies.

13 Sep 2021: We will also be studying lung cancer. Nearly 45,000 new cases of lung cancer are diagnosed annually and nearly 35,000 people die from the disease in the UK every ... Our study aims to: 1) Increase the understanding of how types of breast and lung cancers

30 Apr 2024: Our findings will help both clinical and basic science research in reproductive biology and epigenetics to generate new research questions. ... Culture methods for human placental trophoblast cells are very new and still under development.

30 Apr 2024: Human embryos are highly inaccessible for research. We use animals to test new experimental approaches, and the knowledge gained can be used to investigate similar events in precious human fetuses and ... We have reduced significantly the number of mice

29 Apr 2024: Animals will be brought in and allowed to acclimatise for a few weeks - this helps them to relax in their new surroundings, gets them used to the staff and human contact ... bones, which acts as a shock absorber), to which the new implant/therapy will be

30 Apr 2024: In work under this licence we aim to identify new treatments for CKD, AKI and NAFLD. ... project? We hope to optimise new imaging efficacy endpoints that will allow assessment of animals over time.

13 Sep 2021: However, we sometimes need to breed mice carrying particular genetic modifications to provide early embryos for short-term experiments or to generate new stem cell lines. ... Page 4 of 4. means that we require fewer embryo recipient females for creating

13 Sep 2021: Although stem cells in the brain can make new oligodendrocytes that restore myelin, this regenerative process declines with age. ... Our discoveries may be harnessed to develop new regenerative therapies in the treatment of MS.

20 Aug 2021: Work from this licence is likely to unravel new ways to manipulate the behaviour of these cells and inflammatory responses therapeutically. ... The key aspect of our programme is to visualise neutrophil behaviours in situ by advanced microscopy techniques

30 Apr 2024: For each stock a new generation will be grown every 18 months (3.3 generations per line in 5 years). ... For each we will breed a new generation every 18 months (2560x3.3=8448).