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  2. PPL number: | Granted: 21 Jan 20 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_long-term_effects_of_developmental_hypoxia_on_cardiac_function_nts_redacted.pdf
    19 Aug 2021: These estimates will be updated and recalculated throughout the project as we generate new data.
  3. PPL number: | Granted: 01 Apr 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/evaluation_of_new_devices_to_be_used_in_human_surgery_nts_redacted.pdf
    20 Aug 2021: Page 1 of 8. NON-TECHNICAL SUMMARY. Evaluation of new devices to be used in humansurgery. ... Also, getting new, effective devices/compounds into clinical use as quickly and safely as possible will maximise patient benefits and healthcare savings.
  4. PK and PKPD studies to support Respiratory and Immunology research

    https://www.ubs.admin.cam.ac.uk/system/files/public/pk_and_pkpd_studies_to_support_respiratory_and_immunology_research_non-technical_summary_redacted.pdf
    30 Apr 2024: To enable us to decide what doses of new treatments we need to use in our respiratory and immunology disease models. ... There are multiple stages of non-animal screening of new molecules that are in place before testing in rodent.
  5. Discovery and development of treatments for immunological diseases

    https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_and_development_of_treatments_for_immunological_diseases_non-technical_summary_redacted.pdf
    29 Apr 2024: goal by enabling us to test new therapeutic hypothesis in vivo relevant to new treatments for immune mediate diseases. ... This de-risks again the potential for using new therapeutic agents which are unlikely to achieve active concentrations at the
  6. Neurobehavioural Mechanisms Underlying Mood, Impulsive and Compulsive …

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_impulsive_and_compulsive_mental_health_disorders_non-t_redacted.pdf
    30 Apr 2024: benefit people living with mental health disorders through the development of new treatments. ... We also expect, in the medium term, that our research will lead to the development of new behavioural treatments.
  7. PPL number: | Granted: 20 Nov 19 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/neural_basis_of_spatial_cognition_and_memory_in_the_hippocampus_nts_redacted.pdf
    20 Aug 2021: Importantly, we will study the relationship between the hippocampus (the area of the brain which acts as an internal GPS system and is crucial for remembering new events and navigating) and
  8. Proteotoxicity in development and ageing (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/proteotoxicity_in_development_and_ageing_non-technical_summary_redacted.pdf
    30 Apr 2024: There is no cure for neurodegenerative disorders and thus, finding a new common target is at utmost importance. ... We have created new mouse lines with specific mutations in genes that disrupt one of the stress response pathway that is called
  9. Development of Live Bacterial Therapeutics to treat diseases with…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_to_treat_diseases_with_intestinal_dysbiosis_non-technica_redacted.pdf
    29 Apr 2024: Discoveries made on new bacterial species will be published and available to other researchers. ... We continuously consider their use and development in light of new experimental data.
  10. Development of Molecular Imaging and Theranostic Agents for Cancer…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_molecular_imaging_and_theranostic_agents_for_cancer_and_inflammation_non-technical_s_redacted.pdf
    30 Apr 2024: Some of these methods are aimed at providing information to develop new therapies for these diseases. ... We are developing new ways to image cancer and inflammation and find novel ways of treating these diseases.
  11. Gut hormone modulation of metabolism (non-technical summary)_Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/gut_hormone_modulation_of_metabolism_non-technical_summary_redacted.pdf
    30 Apr 2024: Our findings should guide these attempts and clarify the mechanisms of action these new therapies employ. ... When animals are exposed to new diets or environments they receive training sessions.

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