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211 - 220 of 318 search results for news |u:www.ubs.admin.cam.ac.uk

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  2. PPL number: | Granted: 19 Jun 18 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/genetically_engineered_mouse_models_of_cancer_nts_expires2023_redacted.pdf
    13 Sep 2021: The plan is to generate approximately 10 new models over the course of the licence. ... In this licence we will use lung tumour models to investigate new potential drugs for the treatment of lung cancer.

  3. Understanding Infection Pathogenesis to Guide Therapies…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_infection_pathogenesis_to_guide_therapies_non-technical_summary_redacted.pdf
    30 Apr 2024: 6.1 million deaths annually (https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death). ... This is confounded by the fact that there have been very few new antimicrobial products that have been developed over the last 15 years.

  4. Mechanisms of organ development and disease (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_of_organ_development_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: We will make a new generation for each line every year (5 generations per line). ... In addition, when generating new genetically modified lines, the F0 embryos need to be genotypically screened.

  5. PPL number: | Granted: 20 Aug 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/training_in_advanced_or_complex_procedures_or_devices_nts_redacted.pdf
    13 Sep 2021: For colorectal endoscopic courses, procedures may include a range of new surgical bowel procedures. ... For upper GI endoscopic courses procedures may include tonsillectomy, oesophageal, stomach, duodenal or pancreatic surgery, or other new appropriate

  6. PPL number: | Granted: 26 Nov 20 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/ischaemia_reperfusion_injury_and_organ_transplantation_nts_redacted.pdf
    19 Aug 2021: The treatments that come out of the project may be new intellectual property. ... Altogether, these will generate a blueprint for clinical studies, which will bring successful new treatments to patients.

  7. PPL number: | Granted: 24 May 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/molecular_mechanisms_of_neuronal_excitation_and_neuroinflammation_nts_expires2023_redacted.pdf
    13 Sep 2021: To develop new drugs, it is first necessary to better understand how the nervous system works and what goes wrong in disease: enhanced understanding of how neurones work in health and ... With enhanced knowledge, our work will aid the development of new

  8. PPL number: | Granted: 01 Dec 20 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/radiation_combinations_for_cancer_treatment_nts_redacted.pdf
    19 Aug 2021: With all this information, new clinical trials can be designed that eventually may change clinical practice. ... They are also required by regulatory authorities before any trials of new drugs can be tested in humans.

  9. Interaction between the immune system and tumours (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/interaction_between_the_immune_system_and_tumours_non-technical_summary_redacted.pdf
    30 Apr 2024: To the wider pharmaceutical industry and patients this could lead into the development of new anti-cancer therapies. ... Pilot studies are used to establish the correct dose of reagents/cells, timelines, and to generate baseline data for new experiments.

  10. PPL number: | Granted: 18 Feb 20 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/protection_after_heart_attack_or_stroke_nts_redacted.pdf
    19 Aug 2021: for pilot studies (https://www.nc3rs.org.uk/conducting-pilot-study);. ARRIVE guidelines, https://www.nc3rs.org.uk/arrive-guidelines;. IMPROVE guidelines for stroke models: ... I receive regular updates via the Biological Service of the University of

  11. Development of humanised mouse models for study of cancer…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_humanised_mouse_models_for_study_of_cancer_immunotherapy_non-technical_summary_redacted.pdf
    29 Apr 2024: This could lead to development of new therapies that are more effective and cause fewer side effects to patients. ... More specifically, we expect to generate at least one new therapy and advance it to a stage that it can be investigated further in large

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