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  2. PPL number: | Granted: 06 Aug 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/mice_with_transgenic_immunoglobulin_loci_nts_redacted.pdf
    20 Aug 2021: Given how little innovation there is in veterinary medicine (compared to human medicine), this new class of drugs could have an even bigger impact on pet health than it did on ... In summary: Short-term benefit – New veterinary medicines based on what
  3. PPL number: | Granted: 19 Jun 18 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/genetically_engineered_mouse_models_of_cancer_nts_expires2023_redacted.pdf
    13 Sep 2021: The plan is to generate approximately 10 new models over the course of the licence. ... In this licence we will use lung tumour models to investigate new potential drugs for the treatment of lung cancer.
  4. Mechanisms controlling cell division and cell identity during…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_controlling_cell_division_and_cell_identity_during_development_reprogramming_and_disease_redacted.pdf
    30 Apr 2024: For example, understanding how cell identity can contribute to diseases may help in the discovery of new treatments. ... I am currently on the European Xenopus Resource Steering Committee where new developments in frog husbandry are often discussed.
  5. PPL number: | Granted: 21 Jan 20 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_long-term_effects_of_developmental_hypoxia_on_cardiac_function_nts_redacted.pdf
    19 Aug 2021: These estimates will be updated and recalculated throughout the project as we generate new data.
  6. Models of mitochondrial diseases, pathogenesis and therapy

    https://www.ubs.admin.cam.ac.uk/system/files/public/models_of_mitochondrial_diseases_pathogenesis_and_therapy_non-technical_summary_redacted.pdf
    30 Apr 2024: 1. New mouse models of mitochondrial disease which carry mutations similar to those found in humans. ... The remaining 20% will be neonates (new born pups up to weaning - approx.
  7. 1 Responsibility in the use of animals in bioscience ...

    https://www.ubs.admin.cam.ac.uk/files/animals_in_research.pdf
    8 Jan 2015: The funding bodies encourage researchers to look for opportunities for developing new 3Rs techniques as part of larger programmes of work. ... 21. Communication of advances in the 3RsResearchers should ensure that any new procedures or improvements in
  8. PPL number: | Granted: 24 May 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/molecular_mechanisms_of_neuronal_excitation_and_neuroinflammation_nts_expires2023_redacted.pdf
    13 Sep 2021: To develop new drugs, it is first necessary to better understand how the nervous system works and what goes wrong in disease: enhanced understanding of how neurones work in health and ... With enhanced knowledge, our work will aid the development of new
  9. PPL number: | Granted: 20 Aug 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/training_in_advanced_or_complex_procedures_or_devices_nts_redacted.pdf
    13 Sep 2021: For colorectal endoscopic courses, procedures may include a range of new surgical bowel procedures. ... For upper GI endoscopic courses procedures may include tonsillectomy, oesophageal, stomach, duodenal or pancreatic surgery, or other new appropriate
  10. PPL number: | Granted: 20 Nov 19 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/neural_basis_of_spatial_cognition_and_memory_in_the_hippocampus_nts_redacted.pdf
    20 Aug 2021: Importantly, we will study the relationship between the hippocampus (the area of the brain which acts as an internal GPS system and is crucial for remembering new events and navigating) and
  11. PPL number: | Granted: 26 Nov 20 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/ischaemia_reperfusion_injury_and_organ_transplantation_nts_redacted.pdf
    19 Aug 2021: The treatments that come out of the project may be new intellectual property. ... Altogether, these will generate a blueprint for clinical studies, which will bring successful new treatments to patients.

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