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14 May 2024: The 3Rs Committee wish all the best for her new job in The Netherlands. •

14 May 2024: The committee were pleased to see refinements previously developed with collaborators being brought forward into this new licence. •

28 Feb 2024: Project Licences (a) New licence: The committee discussed the following:. • Further consideration should be given to the lay person in regards to the Non-Technical Summary and this should also be

5 Jul 2023: Project Licences (a) New licence: ( was also in attendance) The committee discussed the following:. •

10 Oct 2023: Project Licences (a) New licence: The committee discussed the following:. • Several typographical errors that require amending. • ... The committee requested a report in 6 months’ time which includes how the new plan for.

17 Jan 2024: around the new proposed protocol. • Further review of Protocol 6 required to ensure all sections have the correct severity. •

10 Oct 2023: b) New Licence: The committee discussed the following:. • Re-wording required in regards to step 3 of Protocol 2. • ... c) New Licence: The committee discussed the following:. • Further explanation required in regards to ageing animals in the

10 Oct 2023: Further details around any new monitoring techniques in the Refinement sections. • ... affected how new licences have been written in Section 4.4. • The committee commended the thorough completion of the Retrospective Review and attention to.

28 Nov 2023: Project Licences (a) New licence: were also in attendance) The committee discussed the following:. • ... The importance of communication the new Licence Holder must have with the animal facility staff on a day to day basis, that they will be

5 Jul 2023: 1d) Apologies: Minutes: 1. Project Licences (a) New licence: was also in attendance) The committee discussed the following:. • ... c) New Licence: The committee discussed the following:. • The recommendation that the applicant reviews the

28 Nov 2023: Consideration given to whether the new objective 6 should apply to Protocols 5 and 6. •

29 Apr 2024: What's the aim of this project? The overall aim of the research is to develop new and improved vaccines. ... New vaccines need to be safe, well tolerated, effective and offer broad coverage against many pathogens.

30 Apr 2024: Our plan is to publish research papers with new information on which human diseases involve programmed axon death and which specific people are most at risk. ... As we have shown, when a new 3Rs method becomes available (e.g., hiPSC-derived neurons), we

30 Apr 2024: Our findings will help both clinical and basic science research in reproductive biology and epigenetics to generate new research questions. ... Culture methods for human placental trophoblast cells are very new and still under development.

29 Apr 2024: Animals will be brought in and allowed to acclimatise for a few weeks - this helps them to relax in their new surroundings, gets them used to the staff and human contact ... bones, which acts as a shock absorber), to which the new implant/therapy will be

30 Apr 2024: Human embryos are highly inaccessible for research. We use animals to test new experimental approaches, and the knowledge gained can be used to investigate similar events in precious human fetuses and ... We have reduced significantly the number of mice

30 Apr 2024: In work under this licence we aim to identify new treatments for CKD, AKI and NAFLD. ... project? We hope to optimise new imaging efficacy endpoints that will allow assessment of animals over time.

30 Apr 2024: For each stock a new generation will be grown every 18 months (3.3 generations per line in 5 years). ... For each we will breed a new generation every 18 months (2560x3.3=8448).

30 Apr 2024: 1. New mouse models of mitochondrial disease which carry mutations similar to those found in humans. ... The remaining 20% will be neonates (new born pups up to weaning - approx.

30 Apr 2024: For example, understanding how cell identity can contribute to diseases may help in the discovery of new treatments. ... I am currently on the European Xenopus Resource Steering Committee where new developments in frog husbandry are often discussed.