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141 - 150 of 158 search results for news |u:www.ubs.admin.cam.ac.uk

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  2. Genes and environment at the interface of inflammation, immunity and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_environment_at_the_interface_of_inflammation_immunity_and_metabolism_non-technical_summa_redacted.pdf
    30 Apr 2024: We will generate new insight into the major biological processes underlying inflammatory diseases. ... This enables the development of new therapeutics, exploiting our discoveries. Species and numbers of animals expected to be used.

  3. Provision of an outsourced drug development platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_development_platform_for_the_treatment_of_bleeding_disorders_non-te_redacted.pdf
    30 Apr 2024: This project will provide important information that aids the progression of new drugs against bleeding disorders through the drug discovery and development process. ... for our studies and to identify any new and better methods that could be utilised.

  4. The genetic and developmental basis of morphological and behavioural…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_genetic_and_developmental_basis_of_morphological_and_behavioural_variation_in_cichlid_fishes_no_redacted.pdf
    30 Apr 2024: We will incorporate new recommendations on animal rearing and welfare as we have done up to now. ... We stay up-to-date with new information and new resources as they become available.

  5. Provision of an outsourced drug discovery platform for metabolic and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_metabolic_and_cardiovascular_diseases_non-te_redacted.pdf
    30 Apr 2024: This project will generate important data in the preclinical development of potential new drugs for metabolic and cardiovascular disease. ... This will include investigation of any potential unwanted side effects that could be caused by the new drugs.

  6. Mechanisms underpinning neuronal excitability in health and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_underpinning_neuronal_excitability_in_health_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Results will open avenues to developing new therapies to treat pain and neurodegeneration. ... Have regular discussions with the Named Persons and animal technicians within the facility to review current approaches and whether there are any new 3Rs

  7. Profiling of test agents in rodents in a drug discovery platform

    https://www.ubs.admin.cam.ac.uk/system/files/public/profiling_of_test_agents_in_rodents_in_a_drug_discovery_platform_non-technical_summary_redacted.pdf
    30 Apr 2024: Ultimately, this project will contribute to the successful development of new drugs, which will benefit patients with the diseases being treated. ... make use of any new knowledge or better methods of performing animal studies.

  8. Provision of an outsourced drug discovery platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_the_development_of_therapeutic_drugs_for_canc_redacted.pdf
    30 Apr 2024: least 5-10 new anti-cancer drugs using these models, or currently available models. ... Mice are the most common type of animal used for developing new cancer treatments.

  9. Remodelling of stem cells and niche cells from development and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/remodelling_of_stem_cells_and_niche_cells_from_development_and_regeneration_to_disease_non-technic_redacted.pdf
    30 Apr 2024: By disseminating our observations from early stages, for example via conferences, we create new collaborations with experts in research fields beyond our own. ... We will carry out pilot studies when new substances, radiation doses, or genetically

  10. Cancer and its microenvironment! From mechanisms to translation…

    https://www.ubs.admin.cam.ac.uk/system/files/public/cancer_and_its_microenvironment_from_mechanisms_to_translation_non-technical_summary_redacted.pdf
    30 Apr 2024: We are following this research field closely and will replace animal research where we can as new technologies develop and are tested and established. ... We also discuss with other groups doing similar research and have an open policy whereby new

  11. Interventions in pregnancy effects of obesity on maternal and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/interventions_in_pregnancy_effects_of_obesity_on_maternal_and_offspring_health_non-technical_summa_redacted.pdf
    30 Apr 2024: Furthermore, we have an extensive tissue bank of samples that can be utilised prior to generating new animal cohorts. ... Our group will attend termly facility user committee meetings where new information is disseminated.

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