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Tau and Alzheimer's - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/lmb-science-stories/tau-and-alzheimers/21 Jul 2023: With recent improvements in electron cryo-microscopy and development of new software that could handle helical samples by Shaoda He in Sjors’ group, they decided to work together to solve the ... Michel: “The most important benefit to emerge from
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Nanobody - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/nanobody/21 Jul 2023: Nanobody Mission The Nanobody facility provides a service for the selection and production of nanobodies from either phage display or yeast surface
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Artists in Residence: Home in the Service of Science - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/events-at-the-lmb/artists-residence-home-service-science/21 Jul 2023: They worked with members of the LMB to inspire new perspectives and understanding of the LMB’s research, both amongst people at the LMB, and the general public.
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Greg Jefferis appointed as Joint Head of the LMB’s Neurobiology…
https://www2.mrc-lmb.cam.ac.uk/greg-jefferis-appointed-as-joint-head-of-the-lmbs-neurobiology-division/9 Oct 2023: Other new research from Greg’s group has identified how flies use smell to determine both the identity and position of other flies, revealing unexpected similarities to the processing of sight ... The Division also investigates the molecular processes
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LMB receives silver LEAF accreditation for sustainable laboratory…
https://www2.mrc-lmb.cam.ac.uk/lmb-receives-silver-leaf-accreditation-for-sustainable-laboratory-practices/19 Feb 2024: The accreditation is awarded to laboratories that can demonstrate practical steps towards improved efficiency and sustainability.
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Scientific Computing - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/scientific-computing/8 Dec 2023: Scientific Computing Scientific Computing provides and supports the LMB’s core Unix systems. These systems include email, authenticating user access to
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Mass Spectrometry - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/mass-spectrometry-home/21 Jul 2023: The development of new mass spectrometric-based methods is essential in order ensure that the LMB remains at the forefront of biological research. ... The group undertakes independent research to create new mass spectrometric technologies and we
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Looking Back: Kathrin Lang - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/looking-back-kathrin-lang/14 Dec 2023: She is now Professor for Chemical Biology at ETH Zurich where she works to develop new tools to study and control biological systems. ... times. Kathrin greeting HM Queen Elizabeth II at the Official Opening of the new LMB Building in 2013.
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From the scientist’s view: a conversation with … Manu Hegde - MRC…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/manu-hegde-a-conversation/21 Jul 2023: This has occurred because when you come across some new finding, you look around and there are people working on certain topics who you are confident will advise you, tell you ... So some people are amazingly technical, they have this mindset of being
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Tanmay Bharat named Blavatnik Award finalist for emerging scientific…
https://www2.mrc-lmb.cam.ac.uk/tanmay-bharat-named-blavatnik-award-finalist-for-emerging-scientific-talent-2/7 Mar 2024: Tanmay Bharat, Group Leader in the LMB’s Structural Studies Division, was honoured by the 2024 Blavatnik Awards in the UK as Finalist in the Life Sciences
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Electron Microscopy - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/electron-microscopy/21 Feb 2024: Electron Microscopy The LMB has an outstanding Electron Microscopy (EM) Facility with a focus on electron cryo-microscopy (cryoEM) of unstained biological
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Venki Ramakrishnan discusses his research career on Digital Science’s …
https://www2.mrc-lmb.cam.ac.uk/venki-ramakrishnan-discusses-his-research-career-on-digital-sciences-tldr-series/15 Apr 2024: Venki Ramakrishnan, Group Leader in the LMB’s Structural Studies Division, is the latest guest on Digital Science’s TL;DR Speaker Series. Topics of
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Overview of admissions - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/students/international-phd-programme/overview-of-admissions/12 Sep 2023: Applicants do not have to make up a new project from thin air!
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The ‘Unknome’ genes which make up a fifth of the human genome - MRC…
https://www2.mrc-lmb.cam.ac.uk/the-unknome-genes-which-make-up-a-fifth-of-the-human-genome/18 Aug 2023: Sean Munro’s group in the LMB’s Cell Biology Division, and Matthew Freeman at the Dunn School of Pathology, University of Oxford, have built the ‘Unknome’
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2002 - Sydney Brenner, Bob Horvitz & John Sulston - MRC…
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/2002-sydney-brenner-bob-horvitz-john-sulston/21 Jul 2023: In parallel with the generation of new cells, cell death is a normal process, both in the foetus and adult, to maintain the appropriate number of cells in tissues. ... This is now being studied in order to improve the diagnosis of disease, develop new
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Activation of the integrated stress response by inhibitors of its…
https://www2.mrc-lmb.cam.ac.uk/activation-of-the-integrated-stress-response-by-inhibitors-of-its-kinases/8 Sep 2023: New research from Anne Bertolotti’s group in the LMB’s Neurobiology Division has discovered unexpected dose-dependent activation, rather than the intended inhibition, of ISR by its kinase inhibitors.
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Electron Cryo-microscopy - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/lmb-science-stories/cryo-electron-microscopy/21 Jul 2023: Electron Cryo-microscopy LMB scientists have been and continue to be at the forefront of the field of electron cryo-microscopy, developing a technique
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A success for the Raymond Nicolet Trust charity cake sale at the LMB…
https://www2.mrc-lmb.cam.ac.uk/a-success-for-the-raymond-nicolet-trust-charity-cake-sale-at-the-lmb/6 Dec 2023: The Raymond Nicolet Trust organised a charity cake sale at the LMB on Monday 21st November. Volunteer patisserie amateurs baked a variety of different
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Crystallography Course 2013 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-training/crystallography-course-2013/21 Jul 2023: Crystallography Course 2013 Lectures Lecture Presentations Tutorials Data Processing and Scaling - Phil Evans and Andrew Leslie Required Software
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From the scientist’s view: a conversation with … Kelly Nguyen - MRC…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/kelly-nguyen-a-conversation/21 Jul 2023: From the scientist’s view: a conversation with … Kelly Nguyen Kelly Nguyen is a Group Leader in the Structural Studies Division at the LMB. She did her
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Joe Greener appointed Group Leader in the LMB’s Structural Studies…
https://www2.mrc-lmb.cam.ac.uk/joe-greener-appointed-group-leader-in-the-lmbs-structural-studies-division/1 Sep 2023: Development of new force fields with optimised parameters to study disordered proteins is a challenging and time-consuming process, particularly when trying to adapt multiple parameters at once.
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Keeping protein subunits in check via assembly quality control - MRC …
https://www2.mrc-lmb.cam.ac.uk/keeping-protein-subunits-in-check-via-assembly-quality-control/21 Jul 2023: Cells eliminate “orphan” proteins that have failed to assemble into the molecular machines within which they normally function. Manu Hegde’s group have now elucidated the mechanism by which one type of orphan is selectively recognised and
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LMB welcomes over 2500 visitors to an action-packed Open Day - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmb-welcomes-over-2500-visitors-to-an-action-packed-open-day/31 Jul 2023: Thank you!”. “I had lots of fun and learned a lot of new stuff, thank you”.
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Support Services - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/support-services/21 Jul 2023: Support services IT Support IT Support provides hardware and software configuration and an extensive and speedy repair service for Apple and Windows
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Setting the stage: development of sample holders for electron…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-exhibitions/setting-the-stage-development-of-sample-holders-for-electron-cryomicroscopy-further-information/21 Jul 2023: Setting the stage: development of sample holders for electron cryomicroscopy. The advancement of microscope sample holders was crucial for moving from
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LMB gets hands-on with a pipetting challenge at the Big Biology Day - …
https://www2.mrc-lmb.cam.ac.uk/lmb-gets-hands-on-with-a-pipetting-challenge-at-the-big-biology-day/26 Oct 2023: The LMB organised an activity for the Big Biology Day focused on highlighting the small scales used in molecular biology
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Benjamin Ryskeldi-Falcon awarded the 2023 SCOR Young European…
https://www2.mrc-lmb.cam.ac.uk/benjamin-ryskeldi-falcon-awarded-the-2023-scor-young-european-researcher-prize/25 Oct 2023: Benjamin Ryskeldi-Falcon, Group Leader in the LMB’s Neurobiology Division, has been recognised for his research into the molecular basis of neurodegenerative diseases.
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Chin
https://www2.mrc-lmb.cam.ac.uk/ccsb/category/publications/feed/3 Apr 2024: W. Chin./p p(124) strongControlling orthogonal ribosome subunit interactions enables evolution of new function. ... James./p p style="padding-left: 60px;"[Featured ina href="http://cen.acs.org/magazine/88/8815.html" target="_blank" rel="noopener -
Phil Holliger appointed Joint Head of the LMB’s Protein and Nucleic…
https://www2.mrc-lmb.cam.ac.uk/phil-holliger-appointed-joint-head-of-the-lmbs-protein-and-nucleic-acid-chemistry-division/20 May 2024: To this end, Phil’s group have developed a new directed evolution technique to improve reverse transcriptase activity for any nucleic acid chemistry, and identified a polymerase enzyme to speed up ... More recently, he and group member Ben Porebski
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Cambridge Festival - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/lmb-on-the-road/cambridge-science-festival/21 Jul 2023: Cambridge Festival The interdisciplinary Cambridge Festival has replaced the Cambridge Science Festival and Cambridge Festival of Ideas in giving the
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Perutz, Steitz and Southgate Prizes awarded to LMB students, postdocs …
https://www2.mrc-lmb.cam.ac.uk/perutz-steitz-and-southgate-prizes-awarded-to-lmb-students-postdocs-and-staff/20 Oct 2023: Jérôme, a Ph.D. student in Jason Chin’s group, was awarded the prize for his pioneering work developing new tools to rapidly and efficiently recode entire genomes and applying this ... Diana’s work has opened up entirely new areas in amyloid
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LMB Open Day 2017 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/events-at-the-lmb/lmb-open-day-2017/21 Jul 2023: LMB Open Day 2017 On Saturday 17th June the LMB held a spectacular Open Day as part of the MRC Festival of Medical Research, welcoming over 2000 visitors
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Radu Aricescu awarded the Karolinska Institutet 2023 Ulf von Euler…
https://www2.mrc-lmb.cam.ac.uk/radu-aricescu-awarded-the-karolinska-institutet-2023-ulf-von-euler-lectureship/12 Sep 2023: We are half way through a most exciting adventure, developing new technologies to understand the fundamental mechanisms of neurotransmission and to put this knowledge to good use.”.
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Biological Services Group - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/biological-services/21 Jul 2023: Biological Services Group The LMB Biological Services Group (BSG) maintains state-of-the-art facilities to house breeding and experimental colonies of
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Daniela Rhodes receives the 2023 WLA Prize in Life Science or…
https://www2.mrc-lmb.cam.ac.uk/daniela-rhodes-receives-the-2023-wla-prize-in-life-science-or-medicine/14 Sep 2023: Daniela Rhodes, Emeritus Scientist in the LMB’s Structural Studies Division, has been awarded the 2023 WLA Prize in Life Science or Medicine.
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Concordat on Openness in Animal Research - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/research/animal-research/concordat-on-openness-in-animal-research/21 Jul 2023: Concordat on Openness in Animal Research The Concordat on Openness is a declaration signed by many organisations involved with bioscience in the UK. The
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A database to identify important genes of unknown function for…
https://www2.mrc-lmb.cam.ac.uk/a-database-to-identify-important-genes-of-unknown-function-for-analysis/9 Aug 2023: Despite decades of work, the role of thousands of human proteins remains unclear despite the likelihood that they participate in possibly new areas of biological function.
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Dina Ratsimandresy’s journey from rural Madagascar to the LMB’s Light …
https://www2.mrc-lmb.cam.ac.uk/dina-ratsimandresys-journey-from-rural-madagascar-to-the-lmbs-light-microscopy-facility/15 Apr 2024: Stellenbosch University highlights Dina Ratsimandresy’s career so far – from studying Mathematics in Madagascar and postgraduate studies in South Africa
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Katja Röper: Development of tubular organs - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/katja-roper-development-of-tubular-organs/21 Jul 2023: I would find it very boring and unproductive if I was so competitive that I felt I had to restrict my lab from talking about new data at meetings.”. ... There’s a new group leaders’ group that meets monthly for lunch and presentations, and the
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Stephen Wallace wins Norman Heatley Award from Royal Society of…
https://www2.mrc-lmb.cam.ac.uk/stephen-wallace-wins-norman-heatley-award-from-royal-society-of-chemistry/21 Jun 2023: LMB 2012-2013, Career Development Fellow, PNAC The Royal Society of Chemistry has announced Stephen Wallace as the 2023 recipient of the Norman Heatley
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Image Processing Software - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/locally-developed-software/image-processing-software/21 Jul 2023: exe. For developing a new program, the following libraries might need to be invoked:.
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Job description and person specification template
https://www2.mrc-lmb.cam.ac.uk/wordpress/?wpdmdl=12061471 Feb 2024: To introduce and apply new techniques across a wide range of disciplines and to have the creativity and initiative to develop novel approaches and methods where required. ... moving into a new research discipline and/or needs to further develop their -
LMB 365 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-365/21 Jul 2023: A great way to meet new people and relax after a busy day in the lab…. ... sites/nextgen/ that brought scientists from academia and industry together to discuss new developments.
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Cheaper microscope could bring protein mapping technique to the…
https://www2.mrc-lmb.cam.ac.uk/auto-draftcheaper-microscope-could-bring-protein-mapping-technique-to-the-massesauto-draft/7 Dec 2023: 7 December, 2023. A news piece in Science highlights how Chris Russo’s group and Richard Henderson, both in the LMB’s Structural Studies Division, have worked with other collaborators to ... build a new cryo–electron microscope at a fraction of
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Ryan Usher and Chris Palmer complete their degrees in Electronics and …
https://www2.mrc-lmb.cam.ac.uk/ryan-usher-and-chris-palmer-complete-their-degrees-in-electronics-and-mechanical-engineering/28 May 2024: The Electronics and Mechanical Engineers share their motivations and experiences of coordinating their university studies with their full-time job.
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William Batey’s apprenticeship experience in the LMB’s Estates and…
https://www2.mrc-lmb.cam.ac.uk/william-bateys-apprenticeship-experience-in-the-lmbs-estates-and-facilities-department/24 Oct 2023: I surveyed the building, ordered new parts and installed new appliances.
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Raphin 1 and phosphatase inhibitors technology (2018) - MRC…
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/raphin1-2018/21 Jul 2023: Overall this new work identifies R15B as a druggable target for Huntington’s disease, and provides the first platform for target-based discovery of inhibitors of serine/threonine phosphatases. ... This novel approach may pave the way to a new
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Low energy cryo-EM to widen accessibility for fast and accurate…
https://www2.mrc-lmb.cam.ac.uk/low-energy-cryo-em-to-widen-accessibility-for-fast-and-accurate-structure-determination/28 Nov 2023: This new electron microscope promises to significantly increase the accessibility of cryo-EM. ... A low-cost electron microscope maps proteins at speed, Nature News. Primary Sidebar.
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Trim-Away™ (2017) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/trim-away-2017/21 Jul 2023: Search this website. Trim-Away (2017). Trim-Away is a new technology, developed by Dean Clift, Melina Schuh and Leo James, for the rapid removal of specific proteins from cells through
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Repurposed DNA repair factors prevent expansions of ‘parasitic’…
https://www2.mrc-lmb.cam.ac.uk/repurposed-dna-repair-factors-prevent-expansions-of-parasitic-genomic-retrotransposons/14 Aug 2023: New research from Nazareno Bona and Gerry Crossan, in the LMB’s PNAC Division, has identified one of these protections against retrotransposons. ... a new site in the genome.
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