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21 Jul 2023: By using such a tractable model system, we can rapidly discover new pathways and dissect mechanisms that may be directly relevant to a number of human diseases, most notably cystic fibrosis ... We use high throughput yeast genetics to identify new

10 Apr 2024: Emmanuel Derivery, Group Leader in the LMB’s Cell Biology Division, is the 2024 recipient of the British Society for Cell Biology’s Hooke Medal.

23 Feb 2024: We are interested in cell autonomous innate immunity, i.e. in the ability of individual cells to defend themselves against infection. Cytosolic defence

9 Oct 2023: Search this website. New deep screening technique enables rapid discovery of high-affinity antibodies to clinically relevant drug targets. ... New deep screening technique enables rapid discovery of high-affinity antibodies to clinically relevant drug

21 Jul 2023: The LMB moved into a new, modern building in February 2013, on the Cambridge Biomedical Campus. ... A new type of immune cell, that can initiate allergic asthma, has been found.

1 Feb 2024: Design of the new building. In keeping with the original ethos of the LMB, the building has an open plan design with many communal areas to encourage interactions and discussions between ... The LMB has a number of initiatives to help employees save

13 Dec 2023: Ordered assembly of a small number of proteins within neurons and, in some cases, glia is a feature of neurodegenerative diseases. These proteins form

1 Feb 2024: In 2013, the LMB moved to a new, purpose-built building designed to deliver the right environment in which innovative medical research, translation and collaboration can flourish. ... Both new and established researchers are encouraged to utilise the

25 Jan 2024: Cell Biology Division The Division aims to understand the biological organisation of cells and organisms, and the molecular mechanisms underlying their

25 Aug 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Julian

6 Sep 2023: Useful Links General: Life at the LMB Postgraduate School of Life Sciences University of Cambridge: Postgraduate Admissions – how to apply to Cambridge

21 Jul 2023: There is emphasis on the development of new technologies, the study of basic biological processes, and the use of this knowledge to tackle specific problems in human health and disease, including ... the development of new therapeutic agents.

21 Jul 2023: In collaboration with our pharmaceutical partners, we are seeking to develop HDX-MS approaches to give better insight into conformational dynamics that could result in new therapeutic strategies.

21 Jul 2023: Past Events Artists in Residence: Home in the Service of Science MRC Festival of Research The WormWatch Lab Imagining the brain competition Crystal

21 Jul 2023: This work led to the realisation that the machine is driven by a mechanical rotary mechanism, a new principle in enzyme function. ... aging, obesity and neuromuscular and neurodegenerative diseases, with the aim of eventually producing new therapies.

6 Mar 2024: She has expanded understanding of the molecular mechanisms which drive amyloid formation, and has discovered several new avenues of research for the field. ... Ultimately, this could prove crucial in the design of new drugs to target different

28 Sep 2023: Search this website. New method to untangle the contribution of signalling pathways involved in asymmetric cell division. ... New method to untangle the contribution of signalling pathways involved in asymmetric cell division.

26 Oct 2023: Knowable magazine covers competing theories as to how organelles such as the nucleus and endoplasmic reticulum came to exist within complex cells. They

21 Jul 2023: Our goal is to understand how the structure of chromatin is involved in transcriptional regulation and how the tips of chromosomes, the telomeres, are

21 Jul 2023: Resources Take a look at our variety of resources. Whether you are looking for an activity to do at home, are a local primary school teacher hoping to

24 Oct 2023: “It is possible that the serotonin in our brains play an essential part in keeping us sane” Sir John Gaddum, 1954 The serotonin (5HT) system is believed

21 Jul 2023: As Deputy Director and Director he was deeply involved in the design and delivery of the new building to which LMB moved in 2013.

5 Jul 2023: At the start of organ development during embryogenesis most animals consist of a simple polarised epithelial sheet of cells that transforms into complex

19 Sep 2023: The group undertakes independent research to develop and implement new mass spectrometry-based methods and they collaborate with LMB groups and apply these bespoke approaches to answer important biological questions. ... Catarina commented: “In 2023, a

21 Jul 2023: Our research has aimed to create a new generation of therapeutic agents, “bicycles”, based on highly constrained peptides with a bicyclic structure and a chemical core.

27 Jul 2023: Search this website. New insights into how DNA synthesis is started during the process of chromosome replication. ... New insights into how DNA synthesis is started during the process of chromosome replication.

25 Jul 2023: Published on. 25 July, 2023. Business Weekly cover recent research from Jason Chin’s group in the LMB’s PNAC Division which details their new technologies for continuous genome synthesis.

25 Aug 2023: Despite extracellular immune surveillance, viral and bacterial pathogens are still able to infect cells. This means each cell must have its own mechanisms

21 Jul 2023: Translation of genetic information into protein is fundamental to life. It is carried out by the large macromolecular machine called the ribosome. In

28 Sep 2023: Stanislau was nominated for was nominated for his research while a PhD student in David Barford’s group in the LMB’s Structural Studies Division.

30 Nov 2023: During his stay with us David also developed new classification software for filaments. ... He worked on in vitro aggregation of tau. Alex went on to do a PhD at the Rockefeller University in New York.

21 Jul 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. T to Z.

25 Aug 2023: Our laboratory uses electron tomography, combined with several structural and cell biology techniques, to study cell surfaces of prokaryotes at the atomic

21 Jul 2023: Tony Crowther’s first degree was in mathematics at Cambridge. After taking a postgraduate diploma in computing, he became a graduate student at the LMB.

21 Jul 2023: years at the University of New South Wales on the structure of carbon fibres.

21 Jul 2023: John Kilmartin started his career as a Ph.D. student with Max Perutz in 1965 working on CO2 transport by haemoglobin and the Bohr effect. He prepared

25 Aug 2023: We have also shown that cryo-EM can be used to identify previously unknown amyloid filaments and new disease entities.

21 Jul 2023: Circadian rhythms are those daily cycles of physiology and behaviour that persist when organisms are isolated from the external world. They are expressed

23 Feb 2024: Asymmetric cell division is the process by which one cell divides into two daughter cells that have different fates. Asymmetric division is the hallmark

21 Jul 2023: Lineage mapping the pre- implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates..

21 Jul 2023: Recently this has focussed on a new graphical user interface (GUI) and developments that will allow more automated data collection and processing, especially at synchrotron beamlines. ... iMosflm: a new graphical interface for diffraction image

21 Jul 2023: Knowledge about the effects of DNA variations among individuals can lead to revolutionary new ways to diagnose, treat, and eventually prevent the thousands of disorders that affect us.

21 Jul 2023: In the early nineties he, together with other groups, discovered new classes of myosins, confirming that myosin exists as a superfamily composed of 18 major classes of motor proteins [Structure (1996) ... One exciting avenue is a recent collaboration set

21 Jul 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Phil Evans

6 Sep 2023: LMB 1967-2006, Group Leader, MRC Retired Worker, Structural Studies After switching scientific disciplines from theoretical chemistry to molecular

20 Feb 2024: elsevier.com/retrieve/pii/S1934-5909(23)00324-7 madeline Thu, 26 Oct 2023 15:29:37 0000 Lab News ... http://science.sciencemag.org/cgi/content/full/science.aaz5626?ijkey=.meiPdSvYLIDw&keytype=ref&siteid=sci#new_tab madeline Fri, 12 Jun 2020 12:41:00 0000

18 Dec 2023: Search this website. Sought FUS, Found TAF—A New Fibril in Frontotemporal Dementia. ... Sought FUS, Found TAF—A New Fibril in Frontotemporal Dementia. Published on.

7 Sep 2023: Search this website. The LMB welcomes Juliette Fedry as a new Group Leader. ... Looking ahead, resulting insights into pathogenesis could facilitate new therapeutic approaches for restoring cellular function.

7 Feb 2024: News highlights from the LMB. Did you know? César Milstein and Georges Köhler developed a technique to produce unlimited quantities of specific monoclonal antibodies, which helped to fuel an international

31 Jul 2023: Every year 20-30 new graduates from the UK and all over the world join the LMB PhD programme.