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15 Nov 2013: Nick’s group have shown that the new ‘ligand trap’ is active in cell culture model systems and are currently testing it in a range of other models. ... The molecule identified in this work is a potentially important therapeutic which could lead to

1 Feb 2013: THE road leading to a new laboratory will be named after renowned scientist Dr Francis Crick. ... Because this road leads to the new laboratory, we wanted someone really prestigious, and what better choicethan Francis,” he added.

18 Dec 2013: KJ Patel, from the LMB’s PNAC Division, has been awarded the Award of Merit for his ‘revolutionary work on aldehyde toxicity in Fanconi anemia

6 Feb 2013: Two factors were crucial to this success. Firstly, they recorded images with much less noise on a new type of direct-electron detector, which was co-developed with the LMB. ... Secondly, because these new cameras are also very fast, they allowed the

1 Nov 2013: Sheffield University researcher Professor Bazbek Davletov took the pain-relieving part of Botox and 'stapled' it to a friendly part of a similar poison

2 May 2013: Dr Michael Neuberger, group leader in the LMB’s Protein and Nucleic Acid Chemistry, has been elected as a Foreign Associate of the US National Academy of

12 Jul 2013:

20 Sep 2013: Approval concludes nearly 40-year epic journey from fundamental research, begun at LMB, to discovery of an effective treatment for active relapsing

22 Jul 2013: Published on. 22 July, 2013. Work carried out by Melina Schuh’s group in the LMB’s Cell Biology Division has provided new insights into how the spindle is asymmetrically positioned

18 Jun 2013: the way industry collaborates with academia and government to share knowledge and discover and develop new drugs. ... Alongside this, the LMB collaborates with industry, both through sharing its talent and ideas with existing companies and by the

28 May 2013: The mysteries of conception were explained to the Queen today as she toured a world-leading research institute dubbed the "Nobel Prize factory". More...

1 Nov 2013: New resource will collect and catalogue stem cells9. New centres put health records at the heart of UK medical research10. ... New research collaborations with China11. Public-private imaging centre to speed drug development12.

10 Sep 2013: of new therapeutics. ... This new technology enhances the speed of the early stage drug screening process, and helps those without the necessary chemistry expertise to more rapidly prepare and test a much greater number

21 Nov 2013: The biochemist, Fred Sanger, a former Head of the LMB's PNAC Division, has died aged 95. He had the rare distinction of winning the Nobel Prize twice, in

27 Jun 2013: Describe the different shapes of viruses and the process viruses use to infect a host cell, replicate, and infect new viruses. ... Ã Understanding how TRIM21 and antibodies work may help scientists devise new therapies for virus infection.

1 Feb 2013: A new line of research in the fight against Alzheimer's diseaseand dementiaJanuary 26 2010. ... Top of page. A new line of research in the fight against Alzheimer's disease.

10 Jul 2013: LMB's David Komander is part of collaborative consortium including FORMA Therapeutics and Cancer Research Technology, aiming to discover cancer drugs

31 May 2013: Work published in the journal Structure by Kiyoshi Nagai’s group in the LMB’s Structural Studies Division, has provided further detailed information on

15 Jul 2013: While fully sequenced genomes are available for many important experimental organisms, a major challenge has been to identify the functions of the genes

28 Jun 2013: public, on Saturday 22 June, to celebrate the opening of its new building and the centenary of the Medical Research Council (MRC). ... Steve joked, to the audience’s delight, about why the new building wouldn’t work and how the LMB could up its Nobel

23 Dec 2013: The G109K substitution has a dramatic ef-fect, because in the new crystals the protein filaments are absent,but dimers are still present (Fig. ... Construction of Plasmids for Protein Purification. pMal-C2X (New EnglandBiolabs) was used to clone and

14 May 2013: structure determination and explains why the development of more. efficient crystallization screens is still challenging (McPherson &. Cudney, 2006). We are constantly testing new conditions and will. eventually integrate them into our

23 Dec 2013: CONTENT ALERTS. more>>article), Receive: RSS Feeds, eTOCs, free email alerts (when new articles cite this.

2 May 2013: Amazing? New? First pacemakers were introduced in the early 1960s. 3 million people worldwide use them. ... rTMS (repetitve transcranial magnetic stimulation) devices are marketed for the treatment of certain types of major depression in Canada, Australia

30 Jul 2013: Nicotinic acetylcholinereceptorandthestructuralbasisofneuromuscular transmission:insightsfromTorpedopostsynapticmembranes. Nigel UnwinMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK. Abstract. The nicotinic

11 Jun 2013: Molecular replacement. New structures from old. The Phase Problem. amplitude. phase.

11 Jun 2013: Molecular replacement. New structures from old. The Phase Problem. amplitude. phase.

19 Mar 2013: C.,and De Camilli, P. (1997) The SH3 domain of amphiphysin binds theproline-rich domain of dynamin at a single site that defines a new SH3binding consensus sequence.

28 May 2013: Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012. ParrotSummary:A new classical density modification program,. employing the latest techniques. ... Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012. Nautilus: A new tool for nucleic acid model building Automated (CCP4i)

21 May 2013: coordinates xyz indicates where the function wants new atoms added. • Substructure completion is done by adding new atoms at these locations and then re-refining. • ... New atoms. Peaks in llg map. Calculating Electron Density • ML function is good

5 Aug 2013: Deubiquitinases Sharpen SubstrateDiscrimination during MembraneProtein Degradation from the ERZai-Rong Zhang,1,3, Juan S. Bonifacino,1 and Ramanujan S. Hegde2,1Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child

10 Jan 2013: information coming from the native data. This new set of phases.

25 Sep 2013: Email alerting service hereright-hand corner of the article or click Receive free email alerts when new articles cite this article - sign up in the box at the top.

13 May 2013: collect data from a new, better crystal – after your return home it will not be quite as easy!Sometimes the best decision is to throw the crystal away and not waste ... if it should be discarded and a new dataset collected on a new crystal.A further

28 May 2013: Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012. ParrotSummary:A new classical density modification program,. employing the latest techniques. ... Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012. Nautilus: A new tool for nucleic acid model building Automated (CCP4i)

21 May 2013: coordinates xyz indicates where the function wants new atoms added. • Substructure completion is done by adding new atoms at these locations and then re-refining. • ... New atoms. Peaks in llg map. Calculating Electron Density • ML function is good

13 May 2013: collect data from a new, better crystal – after your return home it will not be quite as easy!Sometimes the best decision is to throw the crystal away and not waste ... if it should be discarded and a new dataset collected on a new crystal.A further

11 Jun 2013: Molecular replacement. New structures from old. The Phase Problem. amplitude. phase.

28 May 2013: Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012. ParrotSummary:A new classical density modification program,. employing the latest techniques. ... Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012. Nautilus: A new tool for nucleic acid model building Automated (CCP4i)

21 May 2013: coordinates xyz indicates where the function wants new atoms added. • Substructure completion is done by adding new atoms at these locations and then re-refining. • ... New atoms. Peaks in llg map. Calculating Electron Density • ML function is good

13 May 2013: collect data from a new, better crystal – after your return home it will not be quite as easy!Sometimes the best decision is to throw the crystal away and not waste ... if it should be discarded and a new dataset collected on a new crystal.A further