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CURRICULUM VITAE
https://www2.mrc-lmb.cam.ac.uk/groups/bienz/wp-content/uploads/sites/23/BienzCV_March2024.pdf11 Apr 2024: signalling. EMBO J 18, 1630-1641. 60. Yu X, Waltzer L & Bienz M (1999) A new Drosophila APC homologue associated with. ... Science 316, 1619-1622. 93. Tran H, Hamada F, Schwarz-Romond T & Bienz M (2008) Trabid, a new positive regulator of. -
doi:10.1016/j.cell.2008.11.004
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/55_Kang_SW_Cell_2008.pdf21 Nov 2008: redox perturbations), thereby providing a new tool for exploring the ER. ... This new molecular tool can now be combined with the vast collections of yeast strains (deletion, hypomorphic, overexpression, and other mutations) to reveal previously -
LETTERS A bacterial dynamin-like proteinHarry H. Low1 & Jan ...
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/nature%20BDLP%202006.pdf28 Nov 2006: S. & Vallee, R. B.Molecular cloning of the microtubule-associated mechanochemical enzymedynamin reveals homology with a new family of GTP-binding proteins. -
nature structural biology . volume 5 number 6 . june 1998
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/nsb1998.pdf14 Jan 2002: Lloyd, C.W. Microtubules (Wiley-Liss, New York, 1993). 2. 3m. 4C. ... Hol, W.G. Crystal structure of glycosomal glyceraldehyde-3-. phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and new position for the -
7400749.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/41_Ashok_A_EMBORep_2006.pdf19 Jun 2006: Intriguing new studiesindicate a potentially key role for MVB pathways in prion transmis-sion and metabolism, reinforcing the central importance of proteintransport pathways as the molecular basis of various diseases. ... Validation of thisprovocative -
73687_Trans
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/emboj201099s2.pdf28 Apr 2010: There are still questions about how the structure recognizes the very slight curvature of the polar membrane, but the new structural information greatly advances the discussion. -
Jason William Chin Page 1 of 18 MRC Laboratory ...
https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-content/uploads/2024/01/Chin-cv-26012024.pdf29 Jan 2024: 2008. 4: 232-234. [Featured in Nature 2008. 45: 868, Chemistry & Engineering News (ACS). ... 2006. 2: 254-258. [News & Views, Nature Chem. Biol. 2006. 2: 231-232]. -
Crystal Screen Lite™ is a complete reagent kit designed ...
https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB06b.pdf26 Jun 2015: Discard the pipet tip, add a new pipet tip and pipet 1 ml of Crystal Screen Lite reagent 2 into reservoir A2. -
MinCD cell division proteins form alternating copolymeric cytomotive…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/ncomms6341.pdf6 Dec 2014: analyses, we show that MinD activates MinC by forming a new class of alternating. ... We combined our new crystalstructure with the EcMinD dimer structure, revealing twointeresting features (Fig. -
rq5005
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/iucrjS20.pdf28 Jul 2020: L. D. & Kirshner, D. A. (1971). Nature New Biol. 231,. -
M410_8e 231..235
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Dynamin.pdf6 Mar 2001: single site that denes a new SH3 binding consensus sequence. J. ... Medicine, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK. The Oxford Centre for Molecular Sciences, New Chemistry, South Parks Road,Oxford OX1 3QT, UK These authors contributed -
The current approach to initial crystallization screening of proteins …
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Gorrec_undersamplid_2013.pdf14 May 2013: structure determination and explains why the development of more. efficient crystallization screens is still challenging (McPherson &. Cudney, 2006). We are constantly testing new conditions and will. eventually integrate them into our -
pnas201313978 4601..4610
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/pnas2013duman.pdf23 Dec 2013: The G109K substitution has a dramatic ef-fect, because in the new crystals the protein filaments are absent,but dimers are still present (Fig. ... Construction of Plasmids for Protein Purification. pMal-C2X (New EnglandBiolabs) was used to clone and -
1 Supplementary data to accompany paper: Mechanism of endophilin ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/GallopEndophilinEMBO/EndoSupMethods.pdf8 Jun 2006: oxyl-2,2,5,5-tetramethylpyrroline-3-methyl]-methanethiosulfonate) to generate the new side. chain R1 using a previously described protocol (Jao et al., 2004). -
53091 361..366
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/McMahon01020.pdf3 Dec 2004: Theformation of a new vesicle is thought to be driven by both thepolymerization of the coat protein clathrin into a cage-like structureand the selection/modification of membrane lipids5,6. ... solved in the absence of a lipid head group14 (Fig. 2a, -
se060101051p
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/ford01.pdf3 Dec 2004: 17,4943 (1998). 35. A. G. W. Leslie, in Joint CCP4 and ESF-EACMB News-letter on Protein Crystallography No. -
se289900215p
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/strucrev.pdf6 Jul 1999: icle membrane or cellular responses to envi-ronmental stimuli. The developments seenover the past couple of years will continue;new insights and structures will be publishedsoon. ... The challenge for the new century willbe to understand how these -
Cryo-EM reconstruction of AlfA from Bacillus subtilis reveals the…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/AlfA2018.pdf20 Mar 2018: The antiparallel orientation of the. filaments is necessary to ensure that when new protomers areadded to the spindle, it grows in opposite directions and pushes theplasmid copies apart (23). ... FASEB J 9:167–174.36. Krissinel E, Henrick K (2004) -
PII: S0166-2236(03)00131-0
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/25_Hegde_RS_TINS_2003.pdf30 Jun 2003: Clearly, establishingany relationship between PrPSc and cyPrP represents aformidable challenge and will necessitate the developmentof new tools to readily detect and modulate cyPrPformation in precise and selective ways. -
2077 741..748
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/21_Lingappa_VR_BioEssays_2002.pdf5 Jul 2002: Furthermore, new. Table 1. Organizing principles for the levels of complexity in protein folding. ... A new varia-. tion on the translocation of proteins occurs during the early biogenesis of.
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