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26 Sep 2016: Do we even need something new? • Jligand. • Already part of CCP4 • Not really developed • 3D not 2D • Java. •

27 Aug 2022: Select ValidateDifferenceMap Peaks. and hit Find blobs. [The new pop-up contains a clickable list of difference density blobs. ... 7. [We are given a new window to pick what kind of atom/molecule we wishto place here.].

13 Oct 2020: The Hippocrates Additive Screen is a new 48-condition additive screen, containing a library of unique drug-like compounds to enhance protein stability and crystallisability.

18 Jun 2007: Now, MacKinnon and colleagues have used isothermal titration calorimetry (ITC) and new structural data to investigate how ions are selected by KcsA and the contributions they make in promoting the conductive

22 Oct 2002: 2001). Acta Oncol. 40,. 689–695.Peter MacCallum Cancer Institute. subtle implication of this remarkable flexibility remainsTargeting and Beyond:largely ignored.New Roles for Old The ability to tolerate tremendous diversity ... Two new studies (Weihofen

25 Aug 2006: tubulin (orange arrowhead). This new position of helix α4 in the empty state is lower in.

2 Oct 2014: A new set of conditions can easily be achieved by an increase in the salt or PEG concentration, a shift towards one of the two mixed PEGs or even a change ... Anomalous scattering centres The coupling of new crystallization screens with modern methods to

26 Jun 2024: They were however also estimated from the azimuthal data alone. Such an inde- pendent estimate gave new values for the scale factors and axial shifts differing by not more than. ... The positioning indicated in Plate III(b) is the only possibility. This

9 Dec 2016: Dictionary entries. New coordinates (C2), based on above dictionary and REFMAC potentials.

5 Jan 2011: Because the studied compound, HgBa. 2CuO. 4δ,. is thought to be representative of the cuprates, and the new magnetic excitation appears at the same T. ... MedicineIntegrating Medicine. and Science. The new journal from the publisherof Science stands at

23 Nov 2004: new computational model from Scott Bornheimer, Shankar Subra-maniam, and colleagues (University of California, San Diego, CA)predicts how the GTPase cycle operates in one of several modes.

10 Nov 2020: Where does Cryo-EM Coot fit into the various builds/releases? What's new in 0.9 and how does it help? –

19 Dec 2017: So if you click on (sele) you can toggle and untoggle your new selection. ... So if you want to make a new selection, make sure you deselect everything first!

9 Dec 2016: Re-refine. In the updated, Acedrg dictionary, the atom names are the same, one bond is different– Read old model and use new dictionary. – ... I'd rather work in coot and submit refinement jobs, and import and export new models and ligands. –

16 May 2010: Associate the same sequence with the new Helix molecule. • Dock sidechains on the new molecule (it should work if your helix is good). • ... Coot displayes a new molecule that almost fits the so-far unbuilt density.].

3 Mar 2010: Tutorial: Ligand Fitting with Coot. CCP4 Workshop New Delhi 2010. March 3, 2010. ... The centre of the screen is a bit crowded now. Undisplay those new ligands.

26 Jul 2021: Abstract. Many new structures of membrane proteins have been determined over the last decade, yet thenature of protein–lipid interplay has received scant attention. ... Plenum Press, New York). 18. Liu Y-T, Tao C-L, Zhang X, Xia W, Shi D-Q, Qi L, Xu C,

18 Jun 2018: Coot adds intermediate white atoms and pops up a dialog]. • Accept the new atoms. ... Click on an atom in the new ALA. [Coot pops up a residue type chooser]. •

31 Jan 2020: HONOURS AND AWARDS: Apr 2018 Wellcome Investigator Award May 2016 EMBO Membership Dec 2012 Wellcome Trust New Investigator Award Nov 2012 EMBO Young Investigator Program Oct 2010 Elected Fellow of Clare ... Curriculum vitae. Other activities 2020

19 Oct 2022: Coot adds new Buttons for the selected functions in the horizontal tool-bar]. • ... Click on an atom in the new ALA. [ Coot pops up a residue type chooser]. •

2 Aug 2010: Further devel-opment of inhibitors guided by struc-tures could lead to a new generation of improved inhibitors with applications as chemical tools to investigate PtdIns(3)P-dependendent pathways and

1 Jun 2010: This brings the system into a new interacting ground state. c, The new ground state is characterized by identifying the state of the individual ions. ... discover novel quantum phenomena, identify new quantum phases or just design interest-ing quantum

9 Jul 2018: Some additives such as metal divalent cations can induce new crystal contacts. ... New polyols included for cryoprotection of conditions: no need to investigate more conditions for cryo-cooling. •

2 Feb 2004: www.sciencemag.org SCIENCE VOL 303 23 JANUARY 2004 479. One of the basic needs of any growingcell is the ability to remodel the lipidmembranes that both surround the. cell and make up its intracellular organelles.At any point in time, a multitude of

15 Apr 2010: 2008. A novel component of the division-site selection system of Bacillus subtilis and a new mode of action for the division inhibitor MinCD.

24 Oct 2017: The centre of the screen is a bit crowded now. Undisplay those new ligands. ... When we are happy with our fit, we can merge this new ligand into the mainprotein ligand as we did before.

8 Nov 2014: that benefit from bacteria. Validation of. this promising new cell culture model for. ... The power of quantitative proteomics may. well shift how new biological pathways are.

18 Jan 2018: For example, we can introduce new DNA (i.e. make transgenic animals), to express fluorescent proteins in our cells of interest, or we can silence genes to find out what they

4 Jan 2024: 2014). A new system for naming ribosomal proteins. Curr Opin Struct Biol 24C, 165-169. ... coli. In Neutrons in Biology (B.P. Schoenborn, ed.), pp 73-92, Plenum Press, New York.

26 Jul 2023: example on the intranet or through the TC. newsletter or external news stories. ... input. 2) One external news story. highlighting direct technical. input into a recent.

21 Feb 2019: Less stable More interesting Not always clear how to use the new functions. ... or that the new functions are there). A New Branch. New multi-threaded sections: Refinement. –

27 Sep 2021: Using AI to accelerate scientific discoveryWednesday 13th October @ 2.30 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.

27 Sep 2021: KENDREW LECTURE(Part 2). Wednesday 13th October @ 4.00 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.

20 Nov 2009: A new GTPase dimer was created by superimposing the BDLP domain onto the hGBP1 dimer (Ghosh et al., 2006) (see Fig.

8 Sep 2015: Each new top score is highlighted () and the coordinates are updated to the final highest score.

24 Oct 2018: 4 PHE Rotamers. Previous. TraditionalBackrub. Helix-Building. Alpha Helix Placement. Scenario: Looking at a new map, not built with automatic tools: “I can see that there’s a helix here - ... Chemical Features. GUI Updates. Map Properties. The New

10 Jun 2014: The new studies focus on tail-anchored. (TA) membrane proteins, defined topologi-.

8 Oct 2018: Outline. New Tools for Cryo-EM reconstructions Context (experiments) Large-scale movement (morph and jiggle) Alpha Helix fitting Restraints Refinement Back-rub Rotamers cis-peptides Filaments New visualizations. ... Hydrogen Density? New/Bleeding

17 Mar 2004: An important new structure suggests the BAR domainis a membrane-binding module that can both produceand sense membrane curvature. ... 2Department of Physiology and Biophysics, Health ScienceCenter, State University of New York at Stony Brook, StonyBrook,

4 Nov 2022: Science175, 720–731 (1972). 2. R. B. Gennis, Biomembranes: Molecular Structure and Function (Springer-Verlag New York Inc.,1989). ... Nat. New Biol. 236,11–12 (1972). 4. D. Branton, Fracture faces of frozen membranes.

9 Feb 2012: Install BALBES under CCP4 Package (replace a old version with a new one). ... Close the old xterms and open new ones. Re-start ccp4i and select BALBES.

21 Jun 2021: Also, parts can move during specimen translation, making a new contact with small temperature differences between the contacting parts. ... 1996 Bob Morrison of Gatan Inc., designed a holder for a new Phillips prototype to be used with liquid helium.

9 Jan 1998: We were not able to detect largeconformational changes between new and old crystals but themolecule may be fixed in one state by crystal restraints. ... J. Appl. Cryst. 11,268–272 (1978). 27. Brünger, A. X-PLOR Version 3.1, A System for X-ray

22 Feb 2022: at the cellular level in the laboratory and potentially develop new drug treatments. ... Growing human embryos in a new culture system that permits correct development beyond implantation and up to day 13 of development1.

8 Sep 2015: Coot displays a Map Colour Selection window]. • Choose a new colour by clicking on the colour widgets. ... Coot adds intermediate white atoms and pops up a dialog]. • Accept the new atoms.

21 Jan 2010: Coot adds intermediate white atoms and pops up a dialog]. • Accept the new atoms. ... 15. • Now optimize the fit of this new residue with Real Space Refinement.

19 Apr 2006: 2 min per kb of new construct). ... Of course other ways of eliminating the parentalvector from the new product could be used, such as those described by Refs.

9 Dec 2008: the Vps26 domain is present in all eukaryotes—which is good news for plants because they were hitherto thought to completely lack arrestins. ... Trends Biochem Sci 28: 598–603. lefkowitz rJ, rajagopal K, Whalen EJ (2006) new roles for β-arrestins in

29 Sep 2017: new_atom_id _chem_mod_atom.new_type_symbol _chem_mod_atom.new_type_energy _chem_mod_atom.new_charge TMPmod1 delete H2. ... chem_mod_bond.new_type _chem_mod_bond.new_value_dist _chem_mod_bond.new_value_dist_esd TMPmod1 delete C1 H2 single.

30 Apr 2024: J. Comput. Chem. 25, 1605–1612 (2004). 38. W. L. Delano, The PyMOL Graphics System (Version 2.0, Schrödinger, LLC, New York, NY, 2017).39.