Search

23 Feb 2024: In another line of research, we use experimental cryo-EM together with our own image processing developments to discover new protein structures. ... RELION-3: new tools for automated high-resolution cryo-EM structure determination.

26 Mar 2024: Delineating the molecular mechanisms that impart daily rhythms to our biology is therefore important for understanding human health and may provide new insights into the prevention and treatment of many diseases.

5 Jan 2024: preparation. The Passmore lab developed new gold and graphene specimen supports that improve cryo-EM images.

31 Jan 2024: Published on. 31 January, 2024. Jason Chin spoke to BBC’s Roland Pease about his group’s new EcORep orthogonal replication system that enables rapid protein evolution in E.coli and ... how it could help create new substances to be used in medicine &

1 Jul 2024: Synthetic biology enables us to control certain genetic programs and introduce novel phenotypes in model bacteria such as E. coli, though as a field we

21 May 2024: Academy of Medical Sciences The Academy of Medical Sciences is an independent body in the UK that represents the diverse spectrum of medical science –

17 Jan 2024: recollected that Kiyoshi had told her that “It’s never too late to try and learn something new”.

16 May 2024: Each year the Royal Society recognizes excellence in science and technology through its medals, awards and prize lectures and the election of new Fellows.

23 Feb 2024: Our broad goal is to understand how smell turns into behaviour in the fruit fly brain. We currently use a combination of genetic labelling and

23 Feb 2024: The machines that comprise this proteostasis network include the ribosome, which synthesizes new proteins, chaperones that help new proteins fold, and degradation factors that eliminate incorrect or damaged proteins. ... We expect that our results will

15 May 2024: The compartments of the secretory and endocytic pathways are connected by membrane-bound carriers that bud from, and then fuse with, specific organelles.

13 Mar 2024: We also aim to use DMS to develop new force fields at different scales, such as implicit solvent or coarse-grained models, allowing larger systems to be simulated.

29 Apr 2024: 2023: Finally, divisome core complex resolved. Cell division in the vast majority of bacteria depends on the synthesis of new cell wall peptidoglycan and is catalysed by the divisome.

20 May 2024: In 2012 a new chemistry-oriented Centre for Chemical and Synthetic Biology (CCSB) was established, to help support the Division’s work in synthetic biology and strengthen its chemical expertise.

25 Mar 2024: Projects Main applications for October 2024 are now closed. The LMB exceptionally considers applications for research-only MPhil students provided they

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Jan Löwe.

4 Jun 2024: Nigel Unwin became a staff scientist at the LMB in 1968, after obtaining his Ph.D. from Cambridge University. He left the Laboratory in 1980 to become

10 Jan 2024: CryoEM at IUCrJ: a new era.

16 May 2024: Each year, the Fellows of the Royal Society elect up to 85 new Fellows and up to 24 new Foreign Members. ... Alumna Ruth Lehmann joins them as a new Foreign Member of the Royal Society.

23 Feb 2024: Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD) and Amyotrophic Lateral Sclerosis (ALS)

7 Jun 2024: Prior to joining the LMB he founded a company, now situated on the Cambridge Science Park, to apply the Mogrify cell reprogramming technology for the creation of new therapeutics.

16 Feb 2024: Elucidating the molecular details of this pathway was therefore paramount and had the potential to reveal new therapeutic targets for treating cancer.

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Philipp

2 Apr 2024: Search this website. Rising Talent Fellowship. The MRC Laboratory of Molecular Biology (LMB) is proud to launch a new three-year fully funded postdoctoral fellowship for scientists from Black heritage backgrounds. ... This Fellowship is a three-year

10 May 2024: The contents of eukaryotic cells are organised and moved around by motor proteins running along the tracks that make up the cytoskeleton (microtubules and

12 Mar 2024: The brain works as an integrated whole. Animals interact with the world by combining inputs from their senses of vision, hearing, smell, taste, touch and

23 Feb 2024: Precise chromosome replication is essential for maintaining genome stability, yet the process itself is inherently risky. Duplex DNA must be transiently

5 Mar 2024: Molecular motors have critical roles in the trafficking of organelles, vesicles and macromolecules within the cytoplasm, and aberrant motor function is

3 Jun 2024: One of the major tasks that the nervous system faces is that of linking perception to action. We perceive the world around us through our senses and we

23 Feb 2024: Cells are highly compartmentalized into numerous membrane-bound organelles. The membranes that define each organelle contain unique sets of embedded

3 Jun 2024: Pluripotent stem cells have the unique capacity to generate all the cell types of the organism. In the embryo, they undergo concomitant changes in shape

18 Mar 2024: Ultimately, mycobacteria can cause granuloma breakdown by inducing programmed macrophage death, a step that further increases bacterial growth and promotes transmission to new hosts. ... Our findings have been borne out in humans and are informing new

14 Mar 2024: In an effort to better understand human brain development, we have developed a new model system, called cerebral organoids.

1 Jul 2024: Lalita Ramakrishnan, Group Leader in the LMB’s Cell Biology Division and the Molecular Immunity Unit, receives the award in recognition of her pioneering research into tuberculosis.

23 Feb 2024: Science News : Scientists have mapped an insect brain in greater detail than ever before. ... Sky News : First map of insect brain signals 'big step forward' in understanding thoughts.

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Chris Tate

23 Feb 2024: Information transfer in the nervous system occurs at synapses, where presynaptic signals are interpreted by postsynaptic receptors. We study this process

22 Mar 2024: Thus, understanding their cell biology requires re-thinking some of our most basic assumptions (bilayers membranes) and the development of new research tools and methods (high-temperature live cell imaging).

29 Jan 2024: Dendritic cells (DCs) play a key role in initiation of cytotoxic immune responses against pathogens and tumours. In order to prime the relevant T cells,

23 Feb 2024: Our research is aimed at understanding the mechanisms and regulation of chromosome segregation in mitosis. During the cell cycle, accurate chromosome

14 Mar 2024: Andrew Travers started his Ph.D. at the LMB under the tutelage of the late John Smith in 1964. After this he took a couple of years out as a post-doc in

1 Feb 2024: Design of the new building. In keeping with the original ethos of the LMB, the building has an open plan design with many communal areas to encourage interactions and discussions between ... The LMB has a number of initiatives to help employees save

11 Mar 2024: Marta Shahbazi, Group Leader in the LMB’s Cell Biology Division, has been announced as one of the 2024 recipients in the Life Sciences category.

23 Feb 2024: Splicing of precursor messenger RNA (pre-mRNA) is a ubiquitous hallmark of gene expression in all eukaryotes. Within the cell, splicing occurs

13 Feb 2024: Neuronal circuits are the biological substrates for all aspects of brain function such as learning, memory, thought, speech and consciousness. The

23 Feb 2024: We are interested in cell autonomous innate immunity, i.e. in the ability of individual cells to defend themselves against infection. Cytosolic defence

19 Jun 2024: Keren Turton. Earlier this year, the LMB was pleased to appoint Keren Turton as the new Tissue Culture Facility Manager. ... Keren also conducts inductions for new users of the facility so researchers can independently grow cultures.

1 Feb 2024: In 2013, the LMB moved to a new, purpose-built building designed to deliver the right environment in which innovative medical research, translation and collaboration can flourish. ... Both new and established researchers are encouraged to utilise the

22 Mar 2024: Molecular Immunity Unit Menna Clatworthy LMB Division - Molecular Immunity Unit The Clatworthy lab is interested in understanding how B cell activation

2 Feb 2024: Cell shape is adapted to function. Organelle shape and local membrane architectures are likewise optimised for the processes that take place on and within