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29 Apr 2024: Jan Löwe's group at the MRC Laboratory of Molecular Biology. Jan Löwe's ORCID identifier: 0000-0002-5218-6615. For statistics such as h-index and citation numbers please consult Google Scholar: Jan Löwe's profile. 2024. Hale V., Hooker J., Russo C

23 Jul 2024: Carazo, M. Mann & W. Baumeister (2009) "New insights into the molecular architecture of the 26S proteasome". ... S.H.W. Scheres & P. Gros (2001) "Conditional optimization: a new formalism for protein structure refinement".

10 May 2024: The contents of eukaryotic cells are organised and moved around by motor proteins running along the tracks that make up the cytoskeleton (microtubules and

12 Mar 2024: The brain works as an integrated whole. Animals interact with the world by combining inputs from their senses of vision, hearing, smell, taste, touch and

23 Feb 2024: Precise chromosome replication is essential for maintaining genome stability, yet the process itself is inherently risky. Duplex DNA must be transiently

5 Mar 2024: Molecular motors have critical roles in the trafficking of organelles, vesicles and macromolecules within the cytoplasm, and aberrant motor function is

26 Jul 2024: Alumnae Teresa Thurston, Soudabeh Imanikia and Beth Thompson returned to the LMB as speakers at this year’s ‘What Next for Your Career’ event, each offering insights to making career decisions.

23 Feb 2024: Cells are highly compartmentalized into numerous membrane-bound organelles. The membranes that define each organelle contain unique sets of embedded

26 Jul 2024: Tue, 23 Jul 2024 18:03:32 0000 LMB Alumni News https://www2.mrc-lmb.cam.ac.uk/?p=2389062 pLMB 1969-1973, Ph.D. ... Her extensive collection of craft resources has been given a new home at the LMB for anyone to refer to for patterns, information or

3 Jun 2024: Pluripotent stem cells have the unique capacity to generate all the cell types of the organism. In the embryo, they undergo concomitant changes in shape

18 Mar 2024: Ultimately, mycobacteria can cause granuloma breakdown by inducing programmed macrophage death, a step that further increases bacterial growth and promotes transmission to new hosts. ... Our findings have been borne out in humans and are informing new

14 Mar 2024: In an effort to better understand human brain development, we have developed a new model system, called cerebral organoids.

23 Feb 2024: Science News : Scientists have mapped an insect brain in greater detail than ever before. ... Sky News : First map of insect brain signals 'big step forward' in understanding thoughts.

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Chris Tate

23 Feb 2024: Information transfer in the nervous system occurs at synapses, where presynaptic signals are interpreted by postsynaptic receptors. We study this process

22 Mar 2024: Thus, understanding their cell biology requires re-thinking some of our most basic assumptions (bilayers membranes) and the development of new research tools and methods (high-temperature live cell imaging).

29 Jan 2024: Dendritic cells (DCs) play a key role in initiation of cytotoxic immune responses against pathogens and tumours. In order to prime the relevant T cells,

1 Jul 2024: Lalita Ramakrishnan, Group Leader in the LMB’s Cell Biology Division and the Molecular Immunity Unit, receives the award in recognition of her pioneering research into tuberculosis.

23 Feb 2024: Our research is aimed at understanding the mechanisms and regulation of chromosome segregation in mitosis. During the cell cycle, accurate chromosome

14 Mar 2024: Andrew Travers started his Ph.D. at the LMB under the tutelage of the late John Smith in 1964. After this he took a couple of years out as a post-doc in

1 Feb 2024: Design of the new building. In keeping with the original ethos of the LMB, the building has an open plan design with many communal areas to encourage interactions and discussions between ... The LMB has a number of initiatives to help employees save

11 Mar 2024: Marta Shahbazi, Group Leader in the LMB’s Cell Biology Division, has been announced as one of the 2024 recipients in the Life Sciences category.

23 Feb 2024: Splicing of precursor messenger RNA (pre-mRNA) is a ubiquitous hallmark of gene expression in all eukaryotes. Within the cell, splicing occurs

16 Jul 2024: Her extensive collection of craft resources has been given a new home at the LMB for anyone to refer to for patterns, information or inspiration.

13 Feb 2024: Neuronal circuits are the biological substrates for all aspects of brain function such as learning, memory, thought, speech and consciousness. The

23 Feb 2024: We are interested in cell autonomous innate immunity, i.e. in the ability of individual cells to defend themselves against infection. Cytosolic defence

1 Feb 2024: In 2013, the LMB moved to a new, purpose-built building designed to deliver the right environment in which innovative medical research, translation and collaboration can flourish. ... Both new and established researchers are encouraged to utilise the

19 Jun 2024: Keren Turton. Earlier this year, the LMB was pleased to appoint Keren Turton as the new Tissue Culture Facility Manager. ... Keren also conducts inductions for new users of the facility so researchers can independently grow cultures.

22 Mar 2024: Molecular Immunity Unit Menna Clatworthy LMB Division - Molecular Immunity Unit The Clatworthy lab is interested in understanding how B cell activation

2 Feb 2024: Cell shape is adapted to function. Organelle shape and local membrane architectures are likewise optimised for the processes that take place on and within

26 Jul 2024: https://www2.mrc-lmb.cam.ac.uk/news-events/lmb-news/ One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the ... Her extensive collection of craft resources has been given a new

22 Mar 2024: Collaborations with the University of Cambridge LMB scientists from across the Divisions are also involved in various collaborations and initiatives with

10 Apr 2024: Emmanuel Derivery, Group Leader in the LMB’s Cell Biology Division, is the 2024 recipient of the British Society for Cell Biology’s Hooke Medal.

6 Mar 2024: She has expanded understanding of the molecular mechanisms which drive amyloid formation, and has discovered several new avenues of research for the field. ... Ultimately, this could prove crucial in the design of new drugs to target different

13 Jun 2024: Michel Goedert, Group Leader in the LMB’s Neurobiology Division, has been awarded the 2024 Karl Golser Parkinson Prize for his work on the molecular mechanisms of Parkinson’s disease and atypical parkinsonian disorders.

23 Feb 2024: Asymmetric cell division is the process by which one cell divides into two daughter cells that have different fates. Asymmetric division is the hallmark

26 Jul 2024: https://www2.mrc-lmb.cam.ac.uk/news-events/insight-on-research/ One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at ... The novel screening system identified a previously

2 Apr 2024: As an aside, I’m exploring various tools to make new reporters of clock function which will help us get a better overall picture of what is going on inside a

11 Jul 2024: Grazia Spillantini: LMB 1987-1996, Ph.D. Student, Visitor, Scientific Staff, Director’s Division & Neurobiology Podbilewicz: LMB 1991-1996,

31 May 2024: A Blue Sky path to new cancer therapy targets. Investigating the link between amoebae feeding regulation and cancer cell growth. ... New tools for the nucleic acid chemical toolbox. Capitalising on complimentary expertise and technology know-how.

1 May 2024: Electronics Workshop. The Electronics Workshop has been a key factor in the development of new techniques and instrumentation at the LMB since the 1960s. ... The Workshop’s staff are always ready to discuss new projects, helping to develop an initial

1 Feb 2024: The move to a new building in 2013 allowed the LMB to provide much improved facilities across the organisation for those with disabilities.

19 Jan 2024: Funding To carry out a three year PhD with the University of Cambridge, you will need sufficient funds to cover the University fee (your course costs) and

23 Apr 2024: In the summer of 2017, Prof. Cai moved to the University of Manchester as the new chair professor in synthetic genomics. ... Recent research has taken advantage on new advances in high resolution imaging to study the remarkable polarisation that these

1 Feb 2024: Mechanistic understanding of these enzymes has the potential to open new therapeutic opportunities.

21 May 2024: Vogelstein at Johns Hopkins University. This research offers unprecedented insight into neural architecture, and provides a new basis to guide future experimental and theoretical studies into neural circuits and brain function. ... In addition, LMB

10 Jan 2024: the time; how tRNAs, the small RNA molecules that direct the building of new proteins at the ribosome, can in certain circumstances adapt their reading of the genetic code. ... She also began to collaborate with a new young group leader, Hugh Pelham.

12 Mar 2024: reveal a large number of new factors required for organisation of cells by the microtubule motor dynein. ... Follow up studies of one of these factors, the RNA-binding protein SUGP1, provided a proof-of-principle of how the screen can lead to new

26 Jun 2024: LMB Investigator Scientist, Dariusz Czernecki, recently featured on Cambridge 105 Radio’s ‘Polish Waves’ programme. Listen to hear Dariusz chat about his

8 Jul 2024: 12/08/news-article-aggregates-of-tdp-43-protein-spiral-into-view-at-nature-news-views/?utm_source=rss&utm_medium=rss&utm_campaign=news-article-aggregates-of-tdp-43-protein- ... spiral-into-view-at-nature-news-views