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21 Jul 2023: Translation of genetic information into protein is fundamental to life. It is carried out by the large macromolecular machine called the ribosome. In

21 Jul 2023: STEM in Song The LMB atrium was filled with music during STEM in Song as the Girls’ Choir of St Catharine’s College performed songs featuring microbes,

21 Jul 2023: Our goal is to understand how the structure of chromatin is involved in transcriptional regulation and how the tips of chromosomes, the telomeres, are

21 Jul 2023: Other antibodies followed, including BENLYSTA, which promises to be the first new drug treatment for systemic lupus erythematosus (SLE) in 50 years and Abthrax, against infectious anthrax, which has been stockpiled ... In 2007 Richard Henderson and Chris

21 Jul 2023: With recent improvements in electron cryo-microscopy and development of new software that could handle helical samples by Shaoda He in Sjors’ group, they decided to work together to solve the ... Michel: “The most important benefit to emerge from

21 Jul 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Phil Evans

21 Jul 2023: The facility provides researchers with both a service and training in new techniques.

21 Jul 2023: Curios of 60 years of the LMB In an exhibition celebrating 60 years of the LMB, an assortment of curios – unusual and intriguing items – have been

21 Jul 2023: Tony Crowther’s first degree was in mathematics at Cambridge. After taking a postgraduate diploma in computing, he became a graduate student at the LMB.

21 Jul 2023: Nanobody Mission The Nanobody facility provides a service for the selection and production of nanobodies from either phage display or yeast surface

21 Jul 2023: We work on developing new instruments and methods for imaging biological molecules, (DNA, RNA and proteins), at atomic resolution.

21 Jul 2023: Electron Cryo-microscopy LMB scientists have been and continue to be at the forefront of the field of electron cryo-microscopy, developing a technique

8 Dec 2023: Scientific Computing Scientific Computing provides and supports the LMB’s core Unix systems. These systems include email, authenticating user access to

21 Jul 2023: In the early nineties he, together with other groups, discovered new classes of myosins, confirming that myosin exists as a superfamily composed of 18 major classes of motor proteins [Structure (1996) ... One exciting avenue is a recent collaboration set

21 Jul 2023: Setting the stage: development of sample holders for electron cryomicroscopy. The advancement of microscope sample holders was crucial for moving from

21 Jul 2023: John Kilmartin started his career as a Ph.D. student with Max Perutz in 1965 working on CO2 transport by haemoglobin and the Bohr effect. He prepared

21 Jul 2023: The development of new mass spectrometric-based methods is essential in order ensure that the LMB remains at the forefront of biological research. ... The group undertakes independent research to create new mass spectrometric technologies and we

21 Jul 2023: Cambridge Festival The interdisciplinary Cambridge Festival has replaced the Cambridge Science Festival and Cambridge Festival of Ideas in giving the

21 Jul 2023: Lineage mapping the pre- implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates..

21 Jul 2023: Crystallography Course 2013 Lectures Lecture Presentations Tutorials Data Processing and Scaling - Phil Evans and Andrew Leslie Required Software

21 Jul 2023: Proteins, nucleic acids and other biological macromolecules take part in virtually all processes within living organisms. Knowledge of their 3-dimensional

21 Jul 2023: LMB Open Day 2017 On Saturday 17th June the LMB held a spectacular Open Day as part of the MRC Festival of Medical Research, welcoming over 2000 visitors

25 Aug 2023: lead towards new therapeutic targets.

21 Jul 2023: Support services IT Support IT Support provides hardware and software configuration and an extensive and speedy repair service for Apple and Windows

21 Jul 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. H to M.

21 Jul 2023: Biological Services Group The LMB Biological Services Group (BSG) maintains state-of-the-art facilities to house breeding and experimental colonies of

21 Jul 2023: The London International Youth Science Forum (LIYSF) is a two-week residential course for students aged 16-21 who have a keen interest in studying

21 Jul 2023: Alan Fersht was a Natural Sciences undergraduate and Chemistry postgraduate at Gonville and Caius from 1962-68. He was invited to join LMB as a group

21 Jul 2023: Concordat on Openness in Animal Research The Concordat on Openness is a declaration signed by many organisations involved with bioscience in the UK. The

21 Jul 2023: Royal Society Summer Science Exhibitions Each year the Royal Society holds an annual summer science exhibition that showcases the most exciting

21 Jul 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. A to G.

21 Jul 2023: Winners of the 2013-2014 competition Pupils had five weeks to grow the best-looking crystal of Potash Alum that they could. Their crystals were submitted

21 Jul 2023: Overall this new work identifies R15B as a druggable target for Huntington’s disease, and provides the first platform for target-based discovery of inhibitors of serine/threonine phosphatases. ... This novel approach may pave the way to a new

21 Jul 2023: David Neuhaus studied chemistry at St. Edmund Hall Oxford from 1974-78 and then in 1982 obtained his PhD in synthetic organic chemistry at Imperial

21 Jul 2023: exe. For developing a new program, the following libraries might need to be invoked:.

21 Jul 2023: I'm a Scientist, Get Me Out Of Here is an online public engagement event during which scientists talk with school students from all over the UK and answer

25 Aug 2023: Gene transcription is an essential cellular process. Yet, RNA polymerase II (RNAPII) is constantly faced with challenges on its way across the gene. One

21 Jul 2023: Search this website. Trim-Away (2017). Trim-Away is a new technology, developed by Dean Clift, Melina Schuh and Leo James, for the rapid removal of specific proteins from cells through

21 Jul 2023: Schools Visits to the LMB Winning schools were invited to bring students to visit the MRC Laboratory of Molecular Biology in Cambridge for a half-day of

21 Jul 2023: It is now licensed as a treatment for a range of autoimmune diseases and scientists are still discovering new applications. ... Monoclonal antibody technology is behind one third of all new drugs introduced worldwide.

21 Jul 2023: Search this website. Centre for Chemical and Synthetic Biology. Work in the Centre for Chemical and Synthetic Biology (CCSB) aims to develop new approaches to understanding biology at the molecular level, ... both in vitro and in living organisms, and to

21 Jul 2023: As well as being faster, this new type of imaging can reach deeper into solid tissues, such as embryos or tumours. ... The technology has already opened up new possibilities: for macrophotography in biomedical optics, in imaging neurones and mammalian

21 Jul 2023: A great way to meet new people and relax after a busy day in the lab…. ... sites/nextgen/ that brought scientists from academia and industry together to discuss new developments.

21 Jul 2023: Neonatal Mouse Anaesthetisation Mould Request Form Researchers from Dr Ingo Greger’s laboratory at the MRC Laboratory of Molecular Biology have designed a

21 Jul 2023: Crystallisation and X-ray A high quality crystal will amplify the reflections of an intense, monochromatic, beam of light. The resulting diffraction

21 Jul 2023: Bicycle Therapeutics Ltd (2009) Bicycle Therapeutics Ltd is a biotechnology company created in 2009 which has developed a novel technology platform for

21 Jul 2023: A patent application claiming DPEP CPPs was filed in 2017. PepGen, is a new company which spun out in early 2018 and will take forward the development and commercialisation of the

21 Jul 2023: The final formulation of the new 96-condition crystallisation screen integrates 44 compounds overall selected for their relative stability and solubility.

21 Jul 2023: This may in turn lead to the design of new therapeutic strategies aimed at preventing tau dysfunction. ... efforts, such as testing new potential therapeutic entities for prevention, delay or amelioration of neurodegenerative disorders.

21 Jul 2023: CombiPuckTM for X-ray crystallography (2017) Minmin Yu, Adam Fowle, Wai-Ching Hon and Andrew Leslie designed and built a prototype cryopuck (CombiPuckTM)