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  2. Grant Jacobs - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/grant-jacobs/
    Thumbnail for Grant Jacobs - MRC Laboratory of Molecular Biology 17 Nov 2021: Since then he has travelled in Asia and Central Asia, returning to his home country, New Zealand.
  3. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_func_0x6e.html
    24 Aug 2021: new_generic_object_number_for_molecule() : c-interface-generic-objects.h. ... new_molecule_by_symmetry_with_atom_selection() : c-interface.h.
  4. Engaging online for the first Cambridge Festival - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/engaging-online-for-the-first-cambridge-festival/
    Thumbnail for Engaging online for the first Cambridge Festival - MRC Laboratory of Molecular Biology 4 May 2021: LMB scientists contribute to the Cambridge Festival with a livestreamed lab tour and a set of activities showing how studying worms can help us understand our brains
  5. Coot Scripting Interface: get-monomer.hh File Reference

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/get-monomer_8hh.html
    24 Aug 2021: Returns. the new molecule number, if not -1 (error). Generated by . 1.8.5.
  6. Madeline Lancaster appointed as 2021 Vallee Scholar - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-appointed-as-2021-vallee-scholar/
    Thumbnail for Madeline Lancaster appointed as 2021 Vallee Scholar - MRC Laboratory of Molecular Biology 13 Sep 2021: in our brain and produce new virus within choroid plexus (ChP) epithelial cells, which may cause long-term neurological impacts such as chronic fatigue.
  7. How did the chemical reaction of life begin? - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/how-did-the-chemical-reaction-of-life-begin/
    Thumbnail for How did the chemical reaction of life begin? - MRC Laboratory of Molecular Biology 14 Oct 2021: Group Leader John Sutherland discusses his argument that solar UV light is the energy source required to drive the chemical reactions that make the
  8. LMB scientists honoured by Biochemical Society Awards - MRC…

    https://www2.mrc-lmb.cam.ac.uk/lmb-scientists-honoured-by-biochemical-society-awards/
    Thumbnail for LMB scientists honoured by Biochemical Society Awards - MRC Laboratory of Molecular Biology 30 Mar 2021: This award is given every three years to recognise exemplary work leading to the development of a new method or reagent. ... Recently, Maria has used an integrative approach combining data on transcriptomics, genomics, proteomics, receptor sequence and
  9. Pathway behind disposal of ‘orphan’ proteins identified - MRC…

    https://www2.mrc-lmb.cam.ac.uk/pathway-behind-disposal-of-orphan-proteins-identified/
    Thumbnail for Pathway behind disposal of ‘orphan’ proteins identified - MRC Laboratory of Molecular Biology 27 Aug 2021: This new insight, that an assembly factor can also recruit degradation factors such as HERC1, might apply to many other protein complexes in the cell that rely on their own specialised ... Therefore, identification of quality control factors such as
  10. Alex Betz - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/alex-betz/
    Thumbnail for Alex Betz - MRC Laboratory of Molecular Biology 30 Mar 2021: Alexander Betz Alex joined the PNAC Division in 1997 as a Programme Leader Track, before becoming a Programme Leader in 2008. He left the LMB in September
  11. Mike Clark - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/mike-clark/
    Thumbnail for Mike Clark - MRC Laboratory of Molecular Biology 30 Mar 2021: Mike Clark Mike Clark was a Ph.D. student working with Cesar Milstein from 1978-1981 carrying out research into the recently described technology of
  12. Per Bullough - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/lmb-alumni-per-bullough/
    Thumbnail for Per Bullough - MRC Laboratory of Molecular Biology 30 Mar 2021: Search this website. Per Bullough. Per Bullough was a Ph.D. student in the Structural Studies Division at LMB from 1985-1989 developing new methods of low-dose imaging of biological
  13. Geoffrey Grigg (1926 - 2008) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/geoffrey-grigg/
    Thumbnail for Geoffrey Grigg (1926 - 2008) - MRC Laboratory of Molecular Biology 21 May 2021: Geoffrey Grigg (1926 - 2008) Geoffrey Grigg was an Australian visitor to the LMB with Fred Sanger in 1972-1974 and Greg Winter in 1988, and often visited
  14. 2021 Max Perutz Lecture to be given by David Baker - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/2021-max-perutz-lecture-to-be-given-by-david-baker/
    Thumbnail for 2021 Max Perutz Lecture to be given by David Baker - MRC Laboratory of Molecular Biology 20 Apr 2021: This milestone accomplishment highlights the potential of protein engineering to produce new materials to reform and regulate biological systems. ... Our goal is to design a new generation of proteins that address current-day problems not faced during
  15. “The LMB provides an unsurpassed environment for both new ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=18852
    18 Jan 2021: cell type that controls the start of allergic asthma, providing a critical first step in developing new. ... to solve the structureof the ribosome and is. informing work to develop new antibiotics.
  16. Tail of SARS-CoV-2 Spike protein is optimised to reach the cell…

    https://www2.mrc-lmb.cam.ac.uk/tail-of-sars-cov-2-spike-protein-is-optimised-to-reach-the-cell-surface-causing-infection-to-spread-to-neighbouring-cells/
    Thumbnail for Tail of SARS-CoV-2 Spike protein is optimised to reach the cell surface causing infection to spread to neighbouring cells - MRC Laboratory of Molecular Biology 10 Sep 2021: Most of these new Spike proteins accumulate in an intracellular structure named Golgi which assembles new viruses. ... the Golgi apparatus, then hold it there whilst new viruses are made.
  17. Early transcriptional patterning of a forming tissue is essential to…

    https://www2.mrc-lmb.cam.ac.uk/early-transcriptional-patterning-of-a-forming-tissue-is-essential-to-morphogenesis-of-a-tubular-organ/
    Thumbnail for Early transcriptional patterning of a forming tissue is essential to morphogenesis of a tubular organ - MRC Laboratory of Molecular Biology 8 Nov 2021: Time-lapse quantitative study of developing salivary glands in Drosophila embryos, conducted by Katja Röper’s group, reveals the key control factors behind cells’ behavioural transitions that are essential for correct organ formation.
  18. Microscopy, 2021, 1–6doi:https://doi.org/10.1093/jmicro/dfab023…

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/mic21.pdf
    26 Jul 2021: Abstract. Many new structures of membrane proteins have been determined over the last decade, yet thenature of protein–lipid interplay has received scant attention. ... Plenum Press, New York). 18. Liu Y-T, Tao C-L, Zhang X, Xia W, Shi D-Q, Qi L, Xu C,
  19. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x75.html
    24 Aug 2021: update_go_to_atom_window_on_new_mol() : c-interface.h.
  20. ‘Making Visible’ poetic illuminations move to the LMB - MRC…

    https://www2.mrc-lmb.cam.ac.uk/making-visible-poetic-illuminations-move-to-the-lmb/
    Thumbnail for ‘Making Visible’ poetic illuminations move to the LMB - MRC Laboratory of Molecular Biology 10 Dec 2021: Making Visible’ allowed colleagues to connect with each other and explore their scientific work in new, creative ways.
  21. Dan Brown (1923 - 2010) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/dan-brown-1923-2010/
    Thumbnail for Dan Brown (1923 - 2010) - MRC Laboratory of Molecular Biology 30 Mar 2021: Dan Brown 1923 - 2012 It is with great sadness that we report that Dan Brown, who had been battling cancer for some time, died on Tuesday April 24, 2012,
  22. Coot Scripting Interface: cc-interface.hh Source File

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/cc-interface_8hh_source.html
    24 Aug 2021: 474 // return the status and vector of chain-ids of the new chain ids. ... 1312 mmdb::Manager new_molecule_by_symmetry_matrix_from_molecule(mmdb::Manager mol,.
  23. How the fate of immune cell precursors is decided - MRC Laboratory of …

    https://www2.mrc-lmb.cam.ac.uk/how-the-fate-of-immune-cell-precursors-is-decided/
    Thumbnail for How the fate of immune cell precursors is decided - MRC Laboratory of Molecular Biology 11 Jan 2021: 11 January, 2021. Discovery of a new checkpoint that controls the development of innate immune cells with a key role in parasite defence and allergy. ... This led to their proposal of a new transcription factor network to explain how RORα regulates
  24. The Coot User Manual

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot.html
    1 Mar 2021: The Coot User Manual
  25. Behind the scenes: Paul Hart and the development of IT at the LMB -…

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-paul-hart-and-the-development-of-it-at-the-lmb/
    Thumbnail for Behind the scenes: Paul Hart and the development of IT at the LMB - MRC Laboratory of Molecular Biology 20 Dec 2021: The biggest challenge. Several year later the new building project came my way. ... I’d worked on a couple of new building projects, but never as a lead.
  26. Dinolite Instructions

    https://www2.mrc-lmb.cam.ac.uk/microscopes4schools/downloads/dinolite_instructions_detailed_2021.22_LJM.doc
    18 Oct 2021: If no new image appears, move the mouse until it does (you may see the last image taken otherwise). ... 5. To take a new image, place your mouse over anything other than an existing thumbnail.
  27. Coot Scripting Interface: c-interface.h Source File

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h_source.html
    24 Aug 2021: 447. 457 int add_ligand_delete_residue_copy_molecule(int imol_ligand_new,. ... If it doesn't then we /. 1527 / go down a (new 20060920) different path. /.
  28. KENDREW LECTURE(Part 1) Demis HassabisFounder & CEO DeepMind,…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/www2.mrc-lmb.cam.ac.uk/?wpdmdl=21355
    27 Sep 2021: Using AI to accelerate scientific discoveryWednesday 13th October @ 2.30 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  29. KENDREW LECTURE(Part 2) Wednesday 13th October @ 4.00 pmDetails ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/www2.mrc-lmb.cam.ac.uk/?wpdmdl=21356
    27 Sep 2021: KENDREW LECTURE(Part 2). Wednesday 13th October @ 4.00 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  30. Setting the stage: development of sample holders for electron ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=21295
    21 Jun 2021: Also, parts can move during specimen translation, making a new contact with small temperature differences between the contacting parts. ... 1996 Bob Morrison of Gatan Inc., designed a holder for a new Phillips prototype to be used with liquid helium.
  31. Behind the scenes: Maria Daly and the flow cytometry facility - MRC…

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-maria-daly-and-the-flow-cytometry-facility/
    Thumbnail for Behind the scenes: Maria Daly and the flow cytometry facility - MRC Laboratory of Molecular Biology 31 Mar 2021: Behind the scenes: Maria Daly and the flow cytometry facility Maria Daly is manager of the LMB’s Flow Cytometry Facility, which provides LMB scientists
  32. Cryo‐EM structure of the full‐length Lon protease from Thermus…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf
    14 Nov 2021: The new model containing a coiled-coil. a-helix describes map 2 well. ... Hagen WJH, Lindahl E and Scheres SHW (2018) New. tools for automated high-resolution cryo-EM structure.
  33. BIO CHEM ISTR Y Structure of the SARS-CoV-2 RNA-dependent ...

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/SARS%20polym%202021%20e2021946118.full.pdf
    29 Aug 2021: High-resolution structure deter-mination may aid in these directions as new compounds are developed andtested as treatments for COVID-19. ... 9, 2. 021. 20. J. Zivanov et al., New tools for automated high-resolution cryo-EM structuredetermination in
  34. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x64.html
    24 Aug 2021: default_new_atoms_b_factor() : c-interface.h.
  35. Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/francis-crick-1916-2004/
    Thumbnail for Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology 30 Mar 2021: the centre of the new field of molecular biology.
  36. Mark Bretscher - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/mark-bretscher/
    Thumbnail for Mark Bretscher - MRC Laboratory of Molecular Biology 30 Mar 2021: Mark S. Bretscher Mark Bretscher studied Chemistry at the University of Cambridge, before joining the MRC Laboratory of Molecular biology as a research
  37. Heart cell clocks help coordinate daily cardiac function - MRC…

    https://www2.mrc-lmb.cam.ac.uk/heart-cell-clocks-help-coordinate-daily-cardiac-function/
    Thumbnail for Heart cell clocks help coordinate daily cardiac function - MRC Laboratory of Molecular Biology 21 Oct 2021: Cell Biology Group Leader, John O’Neill, discusses his group’s recent paper. Their work highlights how heart cells regulate daily function through
  38. Francis Crick Lecture to be given by Michel C. Nussenzweig - MRC…

    https://www2.mrc-lmb.cam.ac.uk/francis-crick-lecture-to-be-given-by-michel-c-nussenzweig/
    Thumbnail for Francis Crick Lecture to be given by Michel C. Nussenzweig - MRC Laboratory of Molecular Biology 8 Nov 2021: Michel received a B.C. summa cum laude from New York University in 1976, a PhD degree with Ralph Steinman from Rockefeller University in 1981 and an M.D. ... degree from New York University Medical School in 1982. Following this he completed a medical
  39. Wasi Faruqi awarded MBE in Queen’s Birthday Honours - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/wasi-faruqi-awarded-mbe-in-queens-birthday-honours/
    Thumbnail for Wasi Faruqi awarded MBE in Queen’s Birthday Honours - MRC Laboratory of Molecular Biology 14 Jun 2021: Wasi (Abdul Raffey) Faruqi, from the LMB’s Structural Studies Division, has been made a MBE in the Queen’s 2021 Birthday Honours List
  40. Michel Goedert awarded the 2021 Hartwig Piepenbrock-DZNE Prize - MRC…

    https://www2.mrc-lmb.cam.ac.uk/michel-goedert-awarded-the-2021-hartwig-piepenbrock-dzne-prize/
    Thumbnail for Michel Goedert awarded the 2021 Hartwig Piepenbrock-DZNE Prize - MRC Laboratory of Molecular Biology 15 Oct 2021: Hopefully, the new knowledge will lead to the development of safe and effective mechanism-based therapies for common neurodegenerative diseases.”.
  41. Max Perutz (1914 - 2002) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/max-perutz-1914-2002/
    Thumbnail for Max Perutz (1914 - 2002) - MRC Laboratory of Molecular Biology 30 Mar 2021: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures
  42. John Finch Collection - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/scientific-models/john-finch-collection/
    Thumbnail for John Finch Collection - MRC Laboratory of Molecular Biology 31 Mar 2021: He came to the new LMB in 1962 with the Birkbeck group, which was now led by Aaron Klug after Rosalind’s death in 1958.
  43. César Milstein Lecture to be given by Hans Clevers - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/cesar-milstein-lecture-to-be-given-by-hans-clevers/
    Thumbnail for César Milstein Lecture to be given by Hans Clevers - MRC Laboratory of Molecular Biology 23 Nov 2021: Hans Clevers from the Hubrecht Institute will deliver the 2021 César Milstein Lecture on how organoids can be used to model human diseases.
  44. Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/COVID%20vaccine%202021%201873-3468.14171.pdf
    29 Aug 2021: Q5 High-Fidelity 2X Master Mix (New England Biolabs,. Ipswich, MA, USA) as per manufacturer’s instructions.
  45. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_func_0x75.html
    24 Aug 2021: update_go_to_atom_window_on_new_mol() : c-interface.h.
  46. A colourful welcome back for the LMB Arts and Crafts Show - MRC…

    https://www2.mrc-lmb.cam.ac.uk/a-colourful-welcome-back-for-the-lmb-arts-and-crafts-show/
    Thumbnail for A colourful welcome back for the LMB Arts and Crafts Show - MRC Laboratory of Molecular Biology 5 Aug 2021: The LMB Arts and Crafts Show: showcasing the creative talents of the LMB
  47. Madeline Lancaster on serendipity and adventure in science - MRC…

    https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-on-serendipity-and-adventure-in-science/
    Thumbnail for Madeline Lancaster on serendipity and adventure in science - MRC Laboratory of Molecular Biology 22 Sep 2021: Cell Biology Group Leader Madeline Lancaster discusses how her ‘failed’ attempt to grow neural stem cells led to the development of brain organoids –
  48. Dr. George Pieczenik - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/dr-george-pieczenik/
    Thumbnail for Dr. George Pieczenik - MRC Laboratory of Molecular Biology 30 Mar 2021: Dr. George Pieczenik Dr. George Pieczenik worked in the MRC Laboratory of Molecular Biology at intervals during the years 1972-1987. He was an early
  49. Bretscher Archive - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/manuscripts-correspondence/bretscher-archive/
    Thumbnail for Bretscher Archive - MRC Laboratory of Molecular Biology 28 Sep 2021: Search this website. Bretscher Archive. The MRC Unit moved out of the Cavendish Laboratory to the new LMB site in early 1962.
  50. Publications

    https://www2.mrc-lmb.cam.ac.uk/groups/rh15/Publications.html
    14 Apr 2021: Henderson, R. IUCrJ 3, 3-7 (2016). CryoEM at IUCrJ: a new era. ... Caspar, D.L.D. Nature, News & Views 345, 666-667 (1990). Bacteriorhodopsin - at last!
  51. 16262551036386 1..32

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cohesin%20folding%202021%20elife-67268-v1.pdf
    14 Jul 2021: For correspondence:. jyl@mrc-lmb.cam.ac.uk (JL);. ashley.nasmyth@bioch.ox.ac.uk. (KAN). †These authors contributed. equally to this work. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 28. Received:

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