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23 Jun 2021: PIL A, AB, ABC). New Project Licence Holders are now required to complete PIL courses relevant to the work they will be undertaking (see above).

18 Jun 2021: Non-Technical Summaries (Project Licence Abstracts) As part of the project licence application process, applicants must produce a summary (known as a Non-Technical Summary) [ASPA section 5A (1)(e) and (2)(a&b)] of their proposed programme of work.

12 Oct 2021: Search site. University Biomedical Services (UBS). AWERB Standing Committee Redacted Minutes. 2019 AWERB Standing Committee Redacted Minutes. awerb_standing_minutes_300119_redacted.pdf (75.22 KB). awerb_standing_minutes_270219_redacted.pdf (84.18 KB)

20 Aug 2021: Longer-term benefits will be opportunities for making new treatments for controlling fertility in humans.

23 Jun 2021: The PPL course is mandatory training for those who wish to hold a Project Licence. It covers the learning outcomes dictated by the Home Office and helps you understand the requirements for successful experimental design and prepare you for the

9 Sep 2021: evaluation_of_new_devices_to_be_used_in_human_surgery_nts_redacted.pdf (83.93 KB).

23 Jun 2021: From 1st January 2024, the cost of this course is £66.89 for internal candidates and £71.66 for external candidates.

9 Sep 2021: Search site. University Biomedical Services (UBS). 2020. NTS 2020. biobehavioural_basis_of_vulnerability_to_impulsivecompulsive_spectrum_disorders_-_optimisation_and_redacted.pdf (103.11 KB). discovery_of_novel_compounds_for_the_treatment_of_dementia

19 Aug 2021: Understanding the mechanisms that control killing by these cells will improve the design of new immunotherapies. ... We will provide new information on pathways that are required by killer cells of the immune system.

23 Jun 2021: Search site. University Biomedical Services (UBS). PPL Course Content. All new potential PPL applicants/holders should be aware there is a requirement for you to complete the relevant PIL course for

18 Jun 2021: new_treatment_strategies_for_myocardial_infarction_and_aortic_aneurysm_nts_expires2024_redacted.pdf (71.63 KB).

12 Nov 2021: For example, we realise that we must not be complacent and therefore will actively promote, investigate and use new methods of research that can replace animals and only ever use animals

23 Jun 2021: The PPL course is assessed by a series of short answer questions covering ethics, experimental design and Project Licence management. This assessment is completed at home / work and should be returned to UBS within 2 weeks.

23 Jun 2021: Course Content PIL Course A Elements 1. Legislation. 2. Ethics and animal welfare. 3. Biology and husbandry of relevant species. 4. Handling and restraint of relevant species. 5. Animal care and management. 6. Recognition of wellbeing, pain,

23 Jun 2021: 2024 Train the Trainer Course dates Month Deadline Access to the online course material Format Live/in person session January 22nd December 2nd January Online 9th January April 22nd March 1st April In person 10th April June 17th May 28th May

23 Jun 2021: 2024 Nominated Assessor Course dates Month Deadline Access to the online course material Format Live/in person session February 2nd February 12th February Online 19th February April 28th March 8th April In person 16th April June 24th May 3rd June

23 Jun 2021: 2024 Service and Support Staff Course dates Month Deadline Access to the online course material Format Live session April 5th April 8th April In person 23rd April Additional dates can be arranged for sufficient numbers of attendees, either in

13 Sep 2021: Longer-term benefits will be opportunities for making new treatments for controlling fertility in humans.

13 Sep 2021: The work will identify exactly how aneurysms develop and new treatments to prevent this. ... culture. Some aspects of disease including assessment of new treatments still require animal studies.

19 Aug 2021: It also allows for the initial testing of new treatment compounds to assess their compatibility. ... This enables the brain to make new circuits to bypass the damaged neurons.

13 Sep 2021: We will also be studying lung cancer. Nearly 45,000 new cases of lung cancer are diagnosed annually and nearly 35,000 people die from the disease in the UK every ... Our study aims to: 1) Increase the understanding of how types of breast and lung cancers

13 Sep 2021: However, we sometimes need to breed mice carrying particular genetic modifications to provide early embryos for short-term experiments or to generate new stem cell lines. ... Page 4 of 4. means that we require fewer embryo recipient females for creating

13 Sep 2021: Although stem cells in the brain can make new oligodendrocytes that restore myelin, this regenerative process declines with age. ... Our discoveries may be harnessed to develop new regenerative therapies in the treatment of MS.

20 Aug 2021: Work from this licence is likely to unravel new ways to manipulate the behaviour of these cells and inflammatory responses therapeutically. ... The key aspect of our programme is to visualise neutrophil behaviours in situ by advanced microscopy techniques

13 Sep 2021: What's the aim of this project? After food consumption the gut sends signals to the rest of the body preparing it for the arrival of new nutrients. ... We constantly review the literature whilst planning our experiments and acclimatize animals to new

18 Jun 2021: This may be in the form of a new vaccine strategy, or a new anti-viral drug. ... Furthermore, to determine how effective new vaccine approaches are, experimental infections in mice are required.

13 Sep 2021: Our research aims to understand the bases of these disorders, and develop new treatments for them. ... We also aim to use these models to develop new and better treatments for mental health disorders.

20 Aug 2021: Given how little innovation there is in veterinary medicine (compared to human medicine), this new class of drugs could have an even bigger impact on pet health than it did on ... In summary: Short-term benefit – New veterinary medicines based on what

20 Aug 2021: There is a pressing clinical need to identify new types of treatment for human disease (for example, the development of novel antibiotics) and engineered antibodies have considerable potential for this.

13 Sep 2021: Our research will study how and where the bacteria hide in the body to resist to vaccines and antibiotics and will test new innovative vaccines. ... impact of medical treatments and new vaccines on the behaviour of bacteria in an environment that closely

13 Sep 2021: The plan is to generate approximately 10 new models over the course of the licence. ... In this licence we will use lung tumour models to investigate new potential drugs for the treatment of lung cancer.

13 Sep 2021: For colorectal endoscopic courses, procedures may include a range of new surgical bowel procedures. ... For upper GI endoscopic courses procedures may include tonsillectomy, oesophageal, stomach, duodenal or pancreatic surgery, or other new appropriate

13 Sep 2021: To develop new drugs, it is first necessary to better understand how the nervous system works and what goes wrong in disease: enhanced understanding of how neurones work in health and ... With enhanced knowledge, our work will aid the development of new

19 Aug 2021: The treatments that come out of the project may be new intellectual property. ... Altogether, these will generate a blueprint for clinical studies, which will bring successful new treatments to patients.

19 Aug 2021: With all this information, new clinical trials can be designed that eventually may change clinical practice. ... They are also required by regulatory authorities before any trials of new drugs can be tested in humans.

19 Aug 2021: for pilot studies (https://www.nc3rs.org.uk/conducting-pilot-study);. ARRIVE guidelines, https://www.nc3rs.org.uk/arrive-guidelines;. IMPROVE guidelines for stroke models: ... I receive regular updates via the Biological Service of the University of

19 Aug 2021: These estimates will be updated and recalculated throughout the project as we generate new data.

20 Aug 2021: Page 1 of 8. NON-TECHNICAL SUMMARY. Evaluation of new devices to be used in humansurgery. ... Also, getting new, effective devices/compounds into clinical use as quickly and safely as possible will maximise patient benefits and healthcare savings.

20 Aug 2021: Importantly, we will study the relationship between the hippocampus (the area of the brain which acts as an internal GPS system and is crucial for remembering new events and navigating) and

20 Aug 2021: To avoid breeding new mouse strains we will investigate specific immune cells that are labelled.

19 Aug 2021: We hope this will help find new ways to treat or prevent brain disease. ... However, when we develop new techniques, we carefully consider the literature and seek expert advice before starting.

13 Sep 2021: We will perform pilot studies testing any new therapies in very small groups of normal mice. ... These new therapies will have already been tested in isolated cells in the laboratory.

19 Aug 2021: These papers will describe the development of a new type of bone repair material. ... the structure may be compromised, while if it too slow it may adversely affect new bone formation.

19 Aug 2021: basal skin layer, the productive life cycle is triggered and new viruses are produced; iv) PV is shed inside dead cells from the surface of. ... new insight into PV transmission mechanisms, and the development of anti-papillomavirus agents/treatments and

13 Sep 2021: What's the aim of this project? This project aims to discover and develop new ways to treat or prevent malaria transmission and disease. ... As such, the development of new anti-malaria blocking strategies is a major objective.

18 Jun 2021: Page 3 of 10. New genes of interest will be identified and described. ... Thus, finding new biomarkers improves our ability to both detect and treat cancer.

18 Jun 2021: The new insights gained could lead to new strategies for treating such disorders, including learning disabilities and Alzheimer's disease. ... Moreover, our institution's web pages provide regular updates on new developments in the 3Rs.

18 Jun 2021: This network will be utilised to maximise the dissemination of the new knowledge gained through this project. ... 3) By generating large quantities of human cells, where appropriate, we can continue to perform new studies using the same human cells.

13 Sep 2021: The research will aid in the development of new bacterial therapies to treat cancer. ... We continuously consider their use and development in light of new experimental data.

18 Jun 2021: The work will;. 1. Provide new insights into the mechanisms required for regeneration. ... Thus, animal experiments are essential to understand regulatory mechanisms and to design and test potential new therapies.