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What are mini brains? - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/what-are-mini-brains/17 Jan 2018: Shielded by our thick skulls and swaddled in layers of protective tissue, the human brain is extremely difficult to observe in action. Luckily, scientists -
Lalita Ramakrishnan elected to prestigious fellowships - MRC…
https://www2.mrc-lmb.cam.ac.uk/lalita-ramakrishnan-elected-to-prestigious-fellowships/11 May 2018: It seeks to promote excellence in science, electing up to fifty-two new Fellows and up to ten new Foreign Members each year who have made substantial contributions to the improvement ... Findings made in the zebrafish have been borne out in human -
John Sulston (1942 – 2018) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/john-sulston-1942-2018/9 Mar 2018: John Sulston, Nobel Laureate and pioneering scientist on the techniques for mapping of genomes, died on Tuesday 6th March, at the age of 75, after a short -
Ligand Tutorial
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/tutorials/ligand_tutorial/index.html23 Jun 2018: Now open our newly created ligand in Coot:. Click the Coot button (at the bottom of the screen) - this will start a new job that will open Coot to display the ... Click the REFMAC5 button (at the bottom of the screen) - this will start a new job that -
Graeme Mitchison (1944-2018) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/graeme-mitchison-1944-2018-2/30 Apr 2018: Graeme continued to keep in touch with colleagues and friends at LMB, including celebrating the opening of the new LMB building at the LMB Alumni Symposium in 2014. ... Richard Durbin and the LMB News Team. Primary Sidebar. Search. Search this website. -
Alan Brown joins the Department of Biological Chemistry and Molecular …
https://www2.mrc-lmb.cam.ac.uk/alan-brown-joins-department-biological-chemistry-molecular-pharmacology-harvard-medical-school-new-group-leader/1 Mar 2018: Search this website. Alan Brown joins the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School as a new group leader. ... Alan Brown joins the Department of Biological Chemistry and Molecular Pharmacology at Harvard -
BBC Documentary: Inside My Brain - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/bbc-documentary-inside-brain/29 Jan 2018: Charlotte Church is on a scientific journey to explore the cutting edge of mental health research. As part of this, she meets Madeline Lancaster, from the -
Magnetic attraction of AstraZeneca to MRC LMB - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/magnetic-attraction-astrazeneca-mrc-lmb/8 Jan 2018: Published on. 8 January, 2018. AstraZeneca has moved it Nuclear Magnetic Resonance laboratory to the LMB while its new global R&D centre is built nearby. -
Committee on Exiting the EU visits the LMB - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/committee-exiting-eu-visits-lmb/19 Jan 2018: Members of the Committee on Exiting the EU visited the LMB to hold a roundtable discussion with local representatives from science, research, health, -
Biomarker identified by David Komander’s group and collaborators…
https://www2.mrc-lmb.cam.ac.uk/biomarker-identified-by-david-komanders-group-and-collaborators-offers-new-hope-for-foot-and-mouth-detector/15 Mar 2018: Search this website. Biomarker identified by David Komander’s group and collaborators offers new hope for foot-and-mouth detector. ... Biomarker identified by David Komander’s group and collaborators offers new hope for foot-and-mouth detector. -
ProSHADE: ProSHADE Documentation
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/index.html1 Nov 2018: The Lengsin structure box shown in the following figure as semi-transparent grey, while the new box is shown in non-transparent yellow. ... To run another ProSHADE function, a new "run" object needs to be created. -
Max Perutz Lecture to be given by Erin O'Shea - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/max-perutz-lecture-given-erin-oshea/27 Feb 2018: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures -
Michel Goedert is awarded The Brain Prize 2018 - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/michel-goedert-awarded-brain-prize-2018/6 Mar 2018: Michel Goedert from the LMB’s Neurobiology Division has been awarded the 2018 Brain Prize. Michel shares the award with fellow neuroscientists Bart De -
The Science Show – interview with Lori Passmore - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/science-show-interview-lori-passmore/18 Jan 2018: Lori Passmore, from the LMB’s Structural Studies Division, is interviewed for The Science Show on Cambridge 105 Radio. This monthly programme showcases -
Speeding up cargo deliveries in the cell - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/speeding-cargo-deliveries-cell/8 Feb 2018: Cytoplasmic dynein-1, a protein that transports cargos along microtubule tracks throughout the cell, binds to dynactin and cargo adaptor proteins to carry -
LMB alumni involved in the opening of a new state-of-the-art cryo-EM…
https://www2.mrc-lmb.cam.ac.uk/alumni-news-lmb-alumni-involved-in-the-opening-of-a-new-state-of-the-art-cryo-em-facility-at-the-university-of-leicester/12 Apr 2018: LMB alumni involved in the opening of a new state-of-the-art cryo-EM facility at the University of Leicester. ... Published on. 12 April, 2018. A new state-of-the art cryo-EM facility has opened at the University of Leicester. -
I’m a scientist, get me out of here! - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/im-a-scientist-get-me-out-of-here/6 Jul 2018: This year as part of the annual MRC Festival of Medical Research, twenty-five scientists and support staff from across the MRC, including the LMB’s -
Woman of the Week: Madeline Lancaster - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/woman-of-the-week-madeline-lancaster/1 Jun 2018: ‘Woman of the Week’ is Stylist Magazine’s weekly celebration of women making a difference to society. The LMB’s Madeline Lancaster has spent her career -
Richard Henderson made Companion of Honour - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/richard-henderson-made-companion-of-honour/11 Jun 2018: Heptares now has 125 employees and is wholly owned by the Japanese company Sosei, developing new drugs for medically important GPCRs. -
Sjors Scheres is awarded the Bijvoet Medal - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/sjors-scheres-is-awarded-the-bijvoet-medal/27 Apr 2018: Sjors Scheres, Group Leader in the LMB’s Structural Studies Division, has been awarded the Bijvoet Medal for his outstanding contribution to furthering -
The Resolution Revolutionary - Richard Henderson - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/the-resolution-revolutionary-richard-henderson/30 Oct 2018: How an Interest in an obscure branch of physics and faith in electron microscopy led to Richard Henderson winning his Nobel Prize. More... -
Discovery of a sensor for ribosome collisions - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/discovery-of-a-sensor-for-ribosome-collisions/5 Oct 2018: Thus, the new research sheds light on how our body monitors its protein production assembly lines so problems can be promptly resolved before they cause cellular stress and disease. ... In a new study, Szymon investigated what ZNF598 actually recognises, -
Greg Winter wins 2018 Nobel Prize for Chemistry - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/greg-winter-wins-2018-nobel-prize-for-chemistry/3 Oct 2018: Arnold, for developing a method known as phage display and using it for the directed evolution of antibodies, with the aim of producing new pharmaceuticals. ... Today, monoclonal antibodies account for a third of all new treatments. -
How to find the right mentor for you - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/how-to-find-the-right-mentor-for-you/27 Mar 2018: Claudia Bonfio, postdoc in the LMB’s PNAC Division, shares personal experiences of finding the right mentor to help her through the transition from PhD -
Catching enzymes in the act of making an antibiotic - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/catching-enzymes-in-the-act-of-making-an-antibiotic/13 Dec 2018: This approach promises to provide new insight into the acyl intermediates formed by other important enzymes. ... Nature News and Views:Primary Sidebar. Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. -
How replication of DNA is initiated at origins - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/how-replication-of-dna-is-initiated-at-origins/16 Nov 2018: This requires a complex set of machinery called the replisome to unwind the paired strands of DNA allowing different polymerase enzymes to produce new copies. ... A new study from Joseph Yeeles’ group in the LMB’s PNAC Division has shown the first -
LMB raises over £1300 for Prostate Cancer UK - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lmb-raises-over-1300-for-prostate-cancer-uk/14 Dec 2018: LMB staff have raised over £1300 for Prostate Cancer UK at the annual charity Christmas raffle, which was this year supported by a sale of Christmas -
Madan Babu and John Briggs honoured by the Blavatnik Awards - MRC…
https://www2.mrc-lmb.cam.ac.uk/madan-babu-john-briggs-honoured-blavatnik-awards/16 Jan 2018: The Blavatnik Awards at The New York Academy of Sciences honour outstanding young scientists under the age of 42. ... We would like to use this unique opportunity to develop new approaches to better understand how living systems work.”. -
> Home > Software > ProSMART ProSMART - Comparative ...
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/prosmart/prosmart.html13 Dec 2018: >ProSMART - Comparative Structural Analysis and External Restraint Generation. ProSMART (Procrustes Structural Matching Alignment and Restraints Tool) is designed for the conformation-independent comparison of protein structures, and the generation -
M. Madan Babu winner of the 2018 ISCB Innovator Award - MRC…
https://www2.mrc-lmb.cam.ac.uk/m-madan-babu-winner-2018-iscb-innovator-award/15 Feb 2018: to forge new directions. -
Making a cell-based factory for polymer synthesis - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/making-a-cell-based-factory-for-polymer-synthesis/6 Dec 2018: potential to revolutionise the discovery and synthesis of new classes of materials and pharmaceuticals. ... These experiments provide a key advance in the development of cell-based factories that use genetic information to encode the synthesis of new -
Drug designers embrace electron cryo-microscopy - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/drug-designers-embrace-cryo-electron-microscopy/10 Jul 2018: Electron cryo-microscopy is enabling drug designers to understand how protein targets in the body interact with potential therapeutics. Technology -
LMB raises £344.35 at Macmillan Coffee Morning - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lmb-raises-344-35-at-macmillan-coffee-morning/31 Oct 2018: For the fourth year in a row, the LMB’s HR team, supported by colleagues throughout the LMB, raised money for Macmillan Cancer Support by taking part in -
Structure of Pick's tau distinct from AD tau - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/structure-of-picks-tau-distinct-from-ad-tau/10 Sep 2018: In recent years, support has grown for the idea that the same aggregating protein can fold up into different toxic shapes, giving rise to distinct -
How does the replisome respond to DNA damage? - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/how-does-the-replisome-respond-to-dna-damage/1 Jun 2018: Martin and Joe found for the first time that the yeast replisome can re-establish a new leading strand beyond the damage without the assistance of accessory factors, via the activity ... Martin and Joe then pinpointed down the source of this inefficiency -
Discovering how translation and mRNA decay are linked - MRC…
https://www2.mrc-lmb.cam.ac.uk/discovering-how-translation-and-mrna-decay-are-linked/21 Jun 2018: Gel showing global poly(A) tail lengths which shorten over time. Scientists in Lori Passmore’s group in the LMB’s Structural Studies Division have revealed new mechanistic insights into the ... This work provides new insights into the interplay of -
How to be better at networking at conferences - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/how-to-be-better-at-networking-at-conferences/16 May 2018: Claudia Bonfio, postdoc in the LMB’s PNAC Division, shares her top tips on how to enjoy and get the most out of networking at academic conferences. More... -
Max Perutz Lecture to be given by Eric Gouaux - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/max-perutz-lecture-to-be-given-by-eric-gouaux/22 Nov 2018: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures -
Songs fill the atrium at the LMB musical evening - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/songs-fill-the-atrium-at-the-lmb-musical-evening/26 Nov 2018: After the success of the inaugural event last year, the LMB held its second musical evening, once again organised by the LMB Wellbeing Champions and -
First person interview – Thomas Williams (LMB Postdoc) - MRC…
https://www2.mrc-lmb.cam.ac.uk/first-person-interview-thomas-williams-lmb-postdoc/23 May 2018: ‘First Person’ interview with LMB postdoc Thomas Williams about his recent paper, research challenges, mentoring & advice for Early Career -
Complete fly brain images at nanoscale resolution - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/complete-fly-brain-images-at-nanoscale-resolution/30 Jul 2018: A neuroscience milestone: a high-resolution digital snapshot of the adult fruit fly brain. Researchers can now trace the path of any one neuron to any -
Regulation of DNA replication during early embryogenesis - MRC…
https://www2.mrc-lmb.cam.ac.uk/regulation-of-dna-replication-during-early-embryogenesis/9 Mar 2018: Published on. 9 March, 2018. Julian Sale from the LMB’s PNAC Division and collaborators from the Francis Crick Institute and the Department of Zoology have discovered and characterised a new -
‘Mini-brains’: understanding brain growth and disease - MRC…
https://www2.mrc-lmb.cam.ac.uk/mini-brains-understanding-brain-growth-and-disease/30 Apr 2018: Philip Ball, science writer at The Guardian, has had a ‘mini-brain’ grown from a sample of skin from his arm. He talks to the LMB’s Madeline Lancaster, -
Decades of discovery set to revolutionise healthcare - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/decades-of-discovery-set-to-revolutionise-healthcare/1 Nov 2018: A summary of key milestones that show how discovery science has been translated into a novel technology set to revolutionise healthcare. The milestones -
Uncovering the structure of the serotonin receptor - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/uncovering-the-structure-of-the-serotonin-receptor/21 Jun 2018: Understanding the activation mechanism of the serotonin receptor and the mode of binding of a failed anti-migraine drug, donitripan, will hopefully aid the development of new and improved drugs. ... Comparing the new G. o. -receptor structure to other -
Tau filament structures differ between neurodegenerative diseases -…
https://www2.mrc-lmb.cam.ac.uk/tau-filament-structures-differ-between-neurodegenerative-diseases/30 Aug 2018: These new structures show how tau folds in disease-specific ways, providing evidence for the hypothesis that different molecular structures of filamentous tau give rise to the diversity of symptoms between ... Comparison of the new structures of -
Melina Schuh writes about the turning point in her career: becoming a …
https://www2.mrc-lmb.cam.ac.uk/melina-schuh-writes-about-turning-point-in-career/31 Aug 2018: Melina Schuh, a former group leader in the LMB’s Cell Biology Division, has written about her experiences setting up her group at the LMB while also -
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/acedrg-link…
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/acedrg-link-usage-notes.txt14 Mar 2018: Evaluating the script in Coot will provide a new menu item "Acedrg" Clicking on "Make Link with Link Dictionary from Acedrg" will create a new small dialog The bond order can -
Richard Henderson is guest on BBC Radio 4, 'The Life…
https://www2.mrc-lmb.cam.ac.uk/richard-henderson-guest-bbc-radio-4-life-scientific/13 Feb 2018: Richard Henderson talks to Jim Al-Khalili about his childhood, studies and career, specifically his journey working on the development of cryo-electron -
Melina Schuh awarded Biochemical Society Colworth Medal - MRC…
https://www2.mrc-lmb.cam.ac.uk/melina-schuh-awarded-biochemical-society-colworth-medal/23 Apr 2018: Melina Schuh has been awarded the Biochemical Society 2019 Colworth medal. Melina investigates how chromosome segregation errors arise during the meiotic
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