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13 Dec 2018: >ProSMART - Comparative Structural Analysis and External Restraint Generation. ProSMART (Procrustes Structural Matching Alignment and Restraints Tool) is designed for the conformation-independent comparison of protein structures, and the generation

10 Jul 2018: Electron cryo-microscopy is enabling drug designers to understand how protein targets in the body interact with potential therapeutics. Technology

1 Jun 2018: Martin and Joe found for the first time that the yeast replisome can re-establish a new leading strand beyond the damage without the assistance of accessory factors, via the activity ... Martin and Joe then pinpointed down the source of this inefficiency

21 Jun 2018: Gel showing global poly(A) tail lengths which shorten over time. Scientists in Lori Passmore’s group in the LMB’s Structural Studies Division have revealed new mechanistic insights into the ... This work provides new insights into the interplay of

22 Nov 2018: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures

10 Sep 2018: In recent years, support has grown for the idea that the same aggregating protein can fold up into different toxic shapes, giving rise to distinct

16 May 2018: Claudia Bonfio, postdoc in the LMB’s PNAC Division, shares her top tips on how to enjoy and get the most out of networking at academic conferences. More...

26 Nov 2018: After the success of the inaugural event last year, the LMB held its second musical evening, once again organised by the LMB Wellbeing Champions and

23 May 2018: ‘First Person’ interview with LMB postdoc Thomas Williams about his recent paper, research challenges, mentoring & advice for Early Career

30 Jul 2018: A neuroscience milestone: a high-resolution digital snapshot of the adult fruit fly brain.  Researchers can now trace the path of any one neuron to any

9 Mar 2018: Published on. 9 March, 2018. Julian Sale from the LMB’s PNAC Division and collaborators from the Francis Crick Institute and the Department of Zoology have discovered and characterised a new

21 Jun 2018: Understanding the activation mechanism of the serotonin receptor and the mode of binding of a failed anti-migraine drug, donitripan, will hopefully aid the development of new and improved drugs. ... Comparing the new G. o. -receptor structure to other

30 Apr 2018: Philip Ball, science writer at The Guardian, has had a ‘mini-brain’ grown from a sample of skin from his arm. He talks to the LMB’s Madeline Lancaster,

1 Nov 2018: A summary of key milestones that show how discovery science has been translated into a novel technology set to revolutionise healthcare. The milestones

30 Aug 2018: These new structures show how tau folds in disease-specific ways, providing evidence for the hypothesis that different molecular structures of filamentous tau give rise to the diversity of symptoms between ... Comparison of the new structures of

14 May 2018: Founded in 1964 to promote molecular biology in Europe, EMBO elects new members annually on the basis of scientific excellence and outstanding research contributions. ... Her lab also recently developed new specimen supports for electron cryo-microscopy

31 Aug 2018: Melina Schuh, a former group leader in the LMB’s Cell Biology Division, has written about her experiences setting up her group at the LMB while also

14 Mar 2018: Evaluating the script in Coot will provide a new menu item "Acedrg" Clicking on "Make Link with Link Dictionary from Acedrg" will create a new small dialog The bond order can

13 Feb 2018: Richard Henderson talks to Jim Al-Khalili about his childhood, studies and career, specifically his journey working on the development of cryo-electron

23 Apr 2018: Melina Schuh has been awarded the Biochemical Society 2019 Colworth medal.  Melina investigates how chromosome segregation errors arise during the meiotic

3 May 2018: Magdalena Skipper has been appointed editor-in-chief at Nature, becoming the first woman to hold the role in its almost 150-year history. More...

22 Feb 2018: As part of a programme about aging, Rebecca Taylor from the LMB’s Neurobiology Division, talks to presenter Chris Mann about the science behind why we

16 May 2018: He then engineered the best version to be able to copy pieces of itself, and assemble them together into new full synthetic copies. ... This new synthetic biology of triplet based RNA replication might also have biotechnological applications, such as

17 Oct 2018: In 2002, Gero established the principles of optogenetic control and thereby defined a new, now widely used, approach for probing the function of the nervous system. ... Gero studied medicine at the University of Innsbruck in his native Austria and did

19 Apr 2018: Jacques Dubochet will give the 2018 John Kendrew Lecture on Thursday 26th April at 4.00pm in the LMB’s Max Perutz Lecture Theatre.  The title of the

19 Apr 2018: New work from Leo James’ group in the LMB’s PNAC Division has now revealed how TRIM21 is regulated so that it is only switched on at the right time. ... In addition, Leo’s lab has recently developed a new technique, ‘TrimAway’, which uses

31 May 2018: This August marks the centenary of the birth of Fred Sanger, LMB alumnus and one of the most influential scientists of the twentieth century. By devising

14 May 2018: In this week’s science podcast from The Guardian, Madeline Lancaster is interviewed to find out about the mini human brains that she and her group are

4 Jan 2018: This new research has several implications for human health. It provides a simple explanation for how alcohol, which is a source of acetaldehyde, causes genetic damage and therefore acts as a ... In addition, the new insight into the function of p53 in

21 Nov 2018: Dan Brown was a nucleic acids chemist of the highest order, beginning with pioneering work under Lord Alexander Todd in the 1950s at University of

5 Jan 2018: Xiaowei Zhuang will give the 2017 John Kendrew Lecture on Monday 15th January 2018 at 4.00pm in the LMB’s Max Perutz Lecture Theatre. The title of the

23 Mar 2018: Briefly mentioned Coot's new N-linked carbohydrate builder. Note: we are using latest CCP4 expert version. ... But new users will be confused. AP: PE to investigate making some videos.

11 Jun 2018: LIFE LAB events are for everyone – we hope to meet and connect with many new people.”.

18 May 2018: LMB alumni Luca Jovine and Leonid Sazanov have been newly elected as members of the European Molecular Biology Organisation (EMBO), on the basis of their

14 Aug 2018: August 2018 marks the centenary of the birth of Frederick (Fred) Sanger (1918–2013), one of the most influential scientists of the 20th century. Few

17 Dec 2018: The latest recipients of Germany’s most prestigious research prize, the Gottfried Wilhelm Leibniz Prize have been announced, and includes former LMB group

7 Jun 2018: The molecular details elucidated by this new research may open avenues to develop drugs to fight infections and to design complementary therapeutic strategies for some types of cancers.

29 Mar 2018: This work opens new avenues for attempting to manipulate transport in a therapeutic setting.

5 Sep 2018: In order to make new proteins, genes are first transcribed to produce messenger RNA (mRNA) molecules, that are then translated into proteins. ... This means that this new role for tRNAs in the control of gene expression could have a role in human disease.

10 May 2018: Bill Schafer, group leader in the LMB’s Neurobiology Division, has been elected into the Fellowship of the Academy of Medical Sciences. The Academy

17 Oct 2018: After being involved in the discovery of phospho-ubiquitin and its new conformational switch, Christina deciphered the molecular mechanism of parkin activation by phospho-ubiquitin, that parkin phosphorylation is important and

26 Mar 2018: Michel Goedert, winner of Brain Prize 2018, believes our best hope of fighting Alzheimer's disease lies in learning to predict who will get it and

21 Jun 2018: Working out how and where life began is one of the greatest puzzles to solve. The LMB’s Philipp Holliger and John Sutherland, and others, discuss their

31 Aug 2018: Wanda Kukulski, group leader in the LMB’s Cell Biology Division, has been awarded the Royal Microscopical Society’s Alan Agar Medal for Electron

15 Aug 2018: Chain-refine (Shift E). We still have the wrong sequence, let’s apply the new one:.

31 Jan 2018: Sarah Teichamnn has received the Genetics Society’s prestigious Mary Lyon Medal 2018 for “outstanding research” in understanding how the immune system

17 May 2018: These results provide the first evidence of a three-dimensional representation of motor space in the superior colliculus and give new insights into the mechanisms underlying the control of spatially-targeted

2 Feb 2018: Dr Varodom Charoensawan, former PhD student in the LMB’s Structural Studies Division, has been awarded the FAOBMB Young Scientist Award for his work on

14 Jun 2018: Glenn Masson, postdoc in the LMB’s PNAC Division, took part in this year’s Royal Society Parliamentary Pairing Scheme. Read Glenn’s blog to find out more

3 Oct 2018: LMB alumni Susan Shao and Tanmay Bharat are two of the five scientists to be awarded prestigious Vallee Scholarships in 2018. The Vallee Scholars program