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Max Perutz Lecture to be given by Ron Vale - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/max-perutz-lecture-given-ron-vale/26 May 2016: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures
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Allergan signs $3.3bn deal with Heptares - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/allergan-signs-3-3bn-deal-heptares/13 Apr 2016: Heptares Therapeutics, an LMB spin-out company, announces a deal with Allergan for development of novel treatments for neurological disorders, including
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LMB raises £378 at Macmillan Coffee Morning - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lmb-raises-378-macmillan-coffee-morning/19 Oct 2016: For the second year running, the LMB’s HR team, supported by colleagues across the LMB, showed off their baking skills for the Macmillan Cancer Support
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Ramanujan Hegde elected Fellow of the Royal Society - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/ramanujan-hegde-elected-fellow-royal-society/29 Apr 2016: Each year, the Royal Society elects up to 52 new Fellows and up to ten new Foreign Members, recognising those scientists who have made substantial contributions to the improvement of knowledge
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Nanostructures from synthetic genetic polymers - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/nanostructures-synthetic-genetic-polymers/18 Mar 2016: 'Synthetic biology' is a scientific approach that seeks to answer fundamental questions in biology by reconstruction and modification of the molecules and
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LMB rides to victory in National Cycle Challenge - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lmb-rides-victory-national-cycle-challenge/25 Oct 2016: The LMB has continued its winning cycling record by taking first place in its category in the Love to Ride Cambridgeshire event – part of the National
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Structure of brain receptor linked to learning - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/structure-brain-receptor-linked-learning/11 Mar 2016: In addition, AMPA receptors are drug targets and the new structure offers development to novel protein interfaces of the receptor.
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Behind the picture: a tiny cell-killing drill - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/behind-picture-tiny-cell-killing-drill/3 May 2016: Christos Savva, Electron Microscopy Facility scientist at the LMB, talks about why understanding structures of important proteins could be the key to
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LMB scientists talk at the Cambridge Science Festival - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmb-scientists-talk-cambridge-science-festival/23 Mar 2016: As part of the Cambridge Science Festival, two of the LMB’s group leaders talked to the public about their research at the University Technical College
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Apprentices complete their training in the LMB Workshops - MRC…
https://www2.mrc-lmb.cam.ac.uk/apprentices-complete-training-lmb-workshops/26 Aug 2016: Over the past 3 years the LMB has, as part of a Government initiative to provide three million new apprenticeships by 2020, supported two MRC apprentices in the Mechanical and Electronics
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Three LMB scientists elected to EMBO membership - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/three-lmb-scientists-elected-embo-membership-2/23 May 2016: EMBO elects new members annually on the basis of scientific excellence and outstanding research contributions.
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LMB CamAWiSE annual 'What next for your career in science'…
https://www2.mrc-lmb.cam.ac.uk/lmb-camawise-annual-next-career-science-event/13 Jul 2016: Hayley spoke about her decision to do a postdoc in industry in order to pursue a new scientific area and to keep her career options open. ... She encouraged young researchers to be persistent when applying for new positions and highlighted the advantages
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Cambridge Pharmaceutical Cryo-EM Consortium - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/cambridge-pharmaceutical-cryo-em-consortium/5 Apr 2016: Cambridge Pharmaceutical Cryo-EM Consortium formed by FEI, five pharmaceutical companies, LMB and the University of Cambridge. Sample preparation and data
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Madeline Lancaster - The genius who grows tiny brains. - MRC…
https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-genius-grows-tiny-brains/28 Sep 2016: Our brains are complex organic computers – some believe the most complicated in the Universe. Yet one scientist has managed to create mini brains that
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HIV: Newly discovered component could lead to more effective drugs. - …
https://www2.mrc-lmb.cam.ac.uk/hiv-newly-discovered-component-lead-effective-drugs/16 Aug 2016: 16 August, 2016. Collaborative research between Leo James’s group and colleagues at UCL has uncovered key components of HIV, which they believe could lead to new approaches for drugs to
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LMB raises over £1300 for Cancer Research UK - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lmb-raises-over-1300-for-cancer-research-uk/15 Jan 2016: The LMB's annual charity Christmas raffle took place in December 2015. Staff at the LMB raised a total of £1372.85 for Cancer Research UK. This year's
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2016 César Milstein Lecture to be given by Yoshinori Ohsumi - MRC…
https://www2.mrc-lmb.cam.ac.uk/2016-milstein-lecture-given-yoshinori-ohsumi/2 Sep 2016: Yoshinori obtained his Ph.D. from the University of Tokyo. He completed a postdoctoral fellowship at The Rockefeller University in New York working on E.
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Insight into the complex 3D topology of the TOR enzyme - MRC…
https://www2.mrc-lmb.cam.ac.uk/insight-complex-3d-topology-tor-enzyme/15 Apr 2016: Target of Rapamycin (TOR) is a protein kinase that is essential in maintaining cellular homeostasis. In mammalian cells the enzyme occurs as two large
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A protein quality control system for mislocalised proteins - MRC…
https://www2.mrc-lmb.cam.ac.uk/protein-quality-control-system-mislocalised-proteins/23 Jun 2016: Research by Manu Hegde’s lab in the LMB’s Cell Biology Division has found a new protein quality control pathway. ... More generally, a mechanistic understanding of the cell’s protein quality control pathways might eventually lead to new therapeutic
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John Kendrew Lecture to be given by Tony Hunter - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/john-kendrew-lecture-given-tony-hunter/18 May 2016: Tony Hunter will give the delayed John Kendrew Lecture 2015 on Wednesday 25th May 2016 at 15.00 in the LMB’s Max Perutz Lecture Theatre. The title of the
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Mariann Bienz: The Puzzle of Cell Signalling - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/mariann-bienz-the-puzzle-of-cell-signalling/4 Jan 2016: Interview with Mariann Bienz on the mechanisms behind the signalling pathways that switch on gene transcription and how their dysfunction can ultimately
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Richard Pannell "wins science 'Oscar' for his life's …
https://www2.mrc-lmb.cam.ac.uk/richard-pannell-wins-science-oscar-lifes-work/8 Dec 2016: The Haverhill Echo celebrates local resident Richard Pannell's MRC Lifetime Achievement CEO Award. Richard, who was nominated by his current supervisor,
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Steven Brenner named Fellow in International Group - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/steven-brenner-named-fellow-international-group/24 Mar 2016: Former LMB PhD student Steven Brenner has been named a fellow by a prestigious computational biology association for his groundbreaking research in
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2016 John Kendrew Lecture to be given by Bonnie Bassler - MRC…
https://www2.mrc-lmb.cam.ac.uk/2016-john-kendrew-lecture-given-bonnie-bassler/17 Oct 2016: Bonnie’s work also reveals a potential for the development of new classes of broad-spectrum antibiotics.
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Jason Chin elected Fellow of the UK Academy of Medical Sciences - MRC …
https://www2.mrc-lmb.cam.ac.uk/jason-chin-elected-fellow-uk-academy-medical-sciences/28 Apr 2016: It enables scientists to understand and control the function of proteins in cells with unparalleled precision and to produce new proteins.
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More emphasis on doing collaborative research: Meet Nicola Smyllie -…
https://www2.mrc-lmb.cam.ac.uk/emphasis-collaborative-research-meet-nicola-smyllie/27 Jun 2016: Nicola Smyllie, postdoc in LMB's Neurobiology Division, will be talking about “Body clocks: rhythm of life” in Cambridge Market Square on 2nd July 12-3pm
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Molecular basis of APC/C regulation by the spindle assembly…
https://www2.mrc-lmb.cam.ac.uk/molecular-basis-apcc-regulation-spindle-assembly-checkpoint/11 Aug 2016: 11 August, 2016. During eukaryotic cell division (mitosis) the cell’s chromosomes are duplicated and then equally separated into two new daughter cells.
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Art-meets-science performance preview on Cambridge TV - MRC…
https://www2.mrc-lmb.cam.ac.uk/art-meets-science-performance-preview-cambridge-tv/28 Oct 2016: The M.A.C. visited the MRC Laboratory of Molecular Biology to find out about an exciting collaborative performance between the institute's scientists and
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Make academia more family friendly: Meet Danielle Mersch - MRC…
https://www2.mrc-lmb.cam.ac.uk/make-academia-family-friendly-meet-danielle-mersch/29 Jun 2016: Come and learn from Danielle, postdoc in LMB's Neurobiology Division, about “Decoding the fly brain” on 2nd July 2016 12-3pm in Cambridge Market Square.
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Beth Thompson: Data Protection and Medical Research - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/beth-thompson-data-protection-and-medical-research/19 Feb 2016: Former LMB PhD student, Beth Thompson, now works as a Senior Policy Advisor at the Wellcome Trust, focusing on the regulation of research. Beth led
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Scientists Discover a Vulnerability in HIV's Protective Shell. -…
https://www2.mrc-lmb.cam.ac.uk/scientists-discover-vulnerability-hivs-protective-shell/16 Aug 2016: A team of researchers, led by Leo James, has discovered a key feature used by the HIV virus to infect healthy cells without giving itself away and
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Cambridge Fire and Rescue Service run training exercise at LMB - MRC…
https://www2.mrc-lmb.cam.ac.uk/cambridge-fire-rescue-service-run-training-exercise-lmb/6 Dec 2016: The LMB and Cambridge Fire and Rescue Service recently held a joint training exercise, involving six teams from across the region, a silver command unit
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Cryo-EM: The field that came in from the cold - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/cryo-em-the-field-that-came-in-from-the-cold/4 Jan 2016: Recent advances in electron cryo-microscopy are enabling researchers to solve protein structures at near-atomic resolutions, expanding the biological
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An evolutionarily conserved pathway controls proteasome homeostasis - …
https://www2.mrc-lmb.cam.ac.uk/evolutionarily-conserved-pathway-controls-proteasome-homeostasis/28 Jul 2016: Cell survival depends on adaptive signalling pathways to ensure that the supply of vital components matches the fluctuating needs of the cell. The
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John O’Neill receives EMBO Young Investigator Programme Award - MRC…
https://www2.mrc-lmb.cam.ac.uk/john-oneill-receives-embo-young-investigator-programme-award/21 Oct 2016: LMB group leader, John O’Neill, has been elected into the 2016 EMBO Young Investigator Programme. This prestigious programme recognises some of Europe’s
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Ultimate molecular machine plays key role in superbug fight - MRC…
https://www2.mrc-lmb.cam.ac.uk/ultimate-molecular-machine-plays-key-role-superbug-fight/7 Jun 2016: The ribosome is a complex biological machine that plays a central role in all living things and one that, according to Venki Ramakrishnan, could provide
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Richard Henderson wins Royal Society’s prestigious Copley Medal - MRC …
https://www2.mrc-lmb.cam.ac.uk/richard-henderson-wins-royal-societys-prestigious-copley-medal/23 May 2016: The new structures provide important insights into the biological function of the assemblies and, by catalysing the subsequent development of new diagnostic or therapeutic tools, should help to improve the health
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HIV uses capsid pores to import nucleotides and evade innate immunity …
https://www2.mrc-lmb.cam.ac.uk/hiv-uses-capsid-pores-import-nucleotides-evade-innate-immunity/11 Aug 2016: This discovery presents the opportunity to re-evaluate existing treatments for HIV to improve their efficacy as well as a new drug target. ... Understanding how RTIs transit the pores opens new possibilities for improving their delivery.
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2016 Francis Crick Lecture to be given by Adrian Bird - MRC…
https://www2.mrc-lmb.cam.ac.uk/2016-francis-crick-lecture-to-be-given-by-adrian-bird/9 Feb 2016: Adrian Bird will give the 2016 Francis Crick Lecture on Tuesday 16th February 2016 at 11.30am in the Max Perutz Lecture Theatre at the LMB. The lecture,
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Molecular mechanism triggering assembly of the Wnt signalosome…
https://www2.mrc-lmb.cam.ac.uk/molecular-mechanism-triggering-assembly-wnt-signalosome-uncovered/30 Sep 2016: The discovery has led to a new mechanistic model of Wnt signal transduction, in which Wnt-induced clustering of Dishevelled in clathrin-coated pits triggers DEP domain swapping and consequently signalosome
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Lauren Parker Jackson and Kristian Andersen named as Pew Scholars for …
https://www2.mrc-lmb.cam.ac.uk/lauren-parker-jackson-named-pew-scholar-biomedical-sciences/10 Jun 2016: The Pew Charitable Trusts have named 22 exceptional early-career scientists as Pew scholars in the biomedical sciences, including Lauren Parker Jackson
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Vital nutrient has key role in keeping body clocks running on time -…
https://www2.mrc-lmb.cam.ac.uk/vital-nutrient-key-role-keeping-body-clocks-running-time/14 Apr 2016: Magnesium - a nutrient found in many foods - helps control how cells keep their own form of time to cope with the natural environmental cycle of day and
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LMB inspires the next generation of scientists with UTCC student…
https://www2.mrc-lmb.cam.ac.uk/lmb-inspires-next-generation-scientists-utcc-student-interactions/29 Jun 2016: The LMB has continued its collaboration with the University Technical College Cambridge (UTCC), with a series of visits, talks and a challenge project to
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If you can work anywhere, where do you want to work? - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/if-you-can-work-anywhere-where-do-you-want-to-work/29 Feb 2016: An article about modern work spaces featuring the LMB: "It is elegantly fit for purpose, and the purpose, says its director, Sir Hugh Pelham, is "doing
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Richard Henderson wins prize at Carlsberg’s ‘Science to Business’…
https://www2.mrc-lmb.cam.ac.uk/richard-henderson-wins-prize-carlsbergs-science-business-forum/1 Dec 2016: Richard Henderson, group leader at the LMB, has been awarded the Kaj Linderstrøm Lang Prize at Carlsberg’s ‘Science to Business’ Forum in recognition of
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Clotten Foundation Prize 2015 awarded to Professor Terry Rabbitts -…
https://www2.mrc-lmb.cam.ac.uk/clotten-foundation-prize-2015-awarded-professor-terry-rabbitts/15 Jul 2016: Professor Terry Rabbitts has been awarded the inaugural Clotten Foundation Prize 2015 for discoveries on human antibody genes leading to therapeutic
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Madeline Lancaster wins the 2015 3Rs Prize for 3D tissue models - MRC …
https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-wins-the-2015-3rs-prize-for-3d-tissue-models/29 Feb 2016: The paper also describes how the cerebral organoids can be used to model human microcephaly, a disorder recently in the news because of its association with the Zika virus outbreak. ... The development of the ‘cerebral organoids’ has significant
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How one scientist is growing miniature brains in her lab - MRC…
https://www2.mrc-lmb.cam.ac.uk/how-one-scientist-is-growing-miniature-brains-in-her-lab/11 Jan 2016: LMB neuroscientist Madeline Lancaster generates living models of brains from a few stem cells. In her lab, she takes small samples of stem cells and grows
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M. Madan Babu to deliver the Royal Society’s 2016 Francis Crick…
https://www2.mrc-lmb.cam.ac.uk/m-madan-babu-deliver-royal-societys-2016-francis-crick-lecture/24 Nov 2016: M. Madan Babu, a Group Leader in the LMB’s Structural Studies Division, will deliver the annual Francis Crick Lecture at the Royal Society on 7th December
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Daily magnesium fluxes regulate cellular timekeeping and energy…
https://www2.mrc-lmb.cam.ac.uk/daily-magnesium-fluxes-regulate-cellular-timekeeping-energy-balance/14 Apr 2016: These daily magnesium oscillations also affect the circadian rhythm of when ‘clock genes’ are turned on and off, and therefore seem to be a new component of the cell’s biological
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