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8 Jan 2015: The funding bodies encourage researchers to look for opportunities for developing new 3Rs techniques as part of larger programmes of work. ... 21. Communication of advances in the 3RsResearchers should ensure that any new procedures or improvements in

30 Apr 2024: 1. New mouse models of mitochondrial disease which carry mutations similar to those found in humans. ... The remaining 20% will be neonates (new born pups up to weaning - approx.

20 Aug 2021: There is a pressing clinical need to identify new types of treatment for human disease (for example, the development of novel antibiotics) and engineered antibodies have considerable potential for this.

30 Apr 2024: For example, understanding how cell identity can contribute to diseases may help in the discovery of new treatments. ... I am currently on the European Xenopus Resource Steering Committee where new developments in frog husbandry are often discussed.

13 Sep 2021: Our research will study how and where the bacteria hide in the body to resist to vaccines and antibiotics and will test new innovative vaccines. ... impact of medical treatments and new vaccines on the behaviour of bacteria in an environment that closely

13 Sep 2021: The plan is to generate approximately 10 new models over the course of the licence. ... In this licence we will use lung tumour models to investigate new potential drugs for the treatment of lung cancer.

30 Apr 2024: 6.1 million deaths annually (https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death). ... This is confounded by the fact that there have been very few new antimicrobial products that have been developed over the last 15 years.

30 Apr 2024: We will make a new generation for each line every year (5 generations per line). ... In addition, when generating new genetically modified lines, the F0 embryos need to be genotypically screened.

19 Aug 2021: The treatments that come out of the project may be new intellectual property. ... Altogether, these will generate a blueprint for clinical studies, which will bring successful new treatments to patients.

19 Aug 2021: With all this information, new clinical trials can be designed that eventually may change clinical practice. ... They are also required by regulatory authorities before any trials of new drugs can be tested in humans.