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15 Feb 2024: The LMB is saddened to learn of the death of Samantha Skehel, who worked as Grants Manager in the Finance Team and later Technical Officer in the Lab Services and Purchasing Team. Since 2015, she has been based at the Isaac Newton Institute for

8 Oct 2023: Jan Löwe, LMB Director. “The LMB provides an unsurpassed environment for both new and established researchers.

23 Feb 2024: We work on developing new instruments and methods for imaging biological molecules, (DNA, RNA and proteins), at atomic resolution. ... Using this new technology, we study the detailed mechanisms of biomolecules to understand how they function.

21 Jul 2023: For news and public engagement, please contact. ,

23 Feb 2024: In another line of research, we use experimental cryo-EM together with our own image processing developments to discover new protein structures. ... RELION-3: new tools for automated high-resolution cryo-EM structure determination.

21 Jul 2023: LMB Alumni Keeping in touch with our former colleagues and friends is an important part of today’s LMB, celebrating the invaluable work and achievements

26 Mar 2024: Delineating the molecular mechanisms that impart daily rhythms to our biology is therefore important for understanding human health and may provide new insights into the prevention and treatment of many diseases.

21 Jul 2023: Where possible, scientists are encouraged to exploit and disseminate their discoveries – helping to improve quality of life and the economic competitiveness of the UK and pioneering new research methods. ... The LMB’s focus on curiosity-driven

19 Oct 2023: Annette’s aptitude for event organising was again crucial to the Royal Opening of the new LMB building in 2013, when Her late Majesty Queen Elizabeth II and HRH Prince Philip ... A skilled writer herself, Annette also helped publicise research

20 Mar 2024: Search this website. Cambridge startup OutSee Ltd aims to unearth new drug targets with its AI genomics tech. ... Cambridge startup OutSee Ltd aims to unearth new drug targets with its AI genomics tech.

21 Jul 2023: LMB Nobel Prizes Nobel Prizes are international awards administered by the Nobel Foundation in Stockholm, Sweden. They are awarded annually for

21 Jul 2023: Daniel McGillivray Brown Curriculum Vitae Date of Birth: 3 February 1923 Career: Glasgow Academy 1936-1940 Glasgow University 1940-1945 University of

5 Jan 2024: preparation. The Passmore lab developed new gold and graphene specimen supports that improve cryo-EM images.

17 Jan 2024: recollected that Kiyoshi had told her that “It’s never too late to try and learn something new”.

23 Feb 2024: Our broad goal is to understand how smell turns into behaviour in the fruit fly brain. We currently use a combination of genetic labelling and

21 Jul 2023: Doses for X-ray and electron diffraction: New features in RADDOSE-3D including intensity decay models..

31 Jan 2024: Published on. 31 January, 2024. Jason Chin spoke to BBC’s Roland Pease about his group’s new EcORep orthogonal replication system that enables rapid protein evolution in E.coli and ... how it could help create new substances to be used in medicine &

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Jan Löwe.

23 Feb 2024: The machines that comprise this proteostasis network include the ribosome, which synthesizes new proteins, chaperones that help new proteins fold, and degradation factors that eliminate incorrect or damaged proteins. ... We expect that our results will

13 Mar 2024: We also aim to use DMS to develop new force fields at different scales, such as implicit solvent or coarse-grained models, allowing larger systems to be simulated.

25 Mar 2024: Projects Main applications for October 2024 are now closed. The LMB exceptionally considers applications for research-only MPhil students provided they

23 Feb 2024: Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD) and Amyotrophic Lateral Sclerosis (ALS)

25 Aug 2023: Since the orthogonal ribosome, unlike the natural ribosome, is not essential it is possible to evolve the orthogonal ribosome to read new genetic codes on the orthogonal message. ... This parallel translation pathway provides a series of blank codons

10 Jan 2024: CryoEM at IUCrJ: a new era.

21 Jul 2023: Photographs The LMB has an extensive collection of photographs and images, a selection of which can be viewed here by either browsing the collection or

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Philipp

16 Feb 2024: Elucidating the molecular details of this pathway was therefore paramount and had the potential to reveal new therapeutic targets for treating cancer.

21 Jul 2023: Mark S. Bretscher Curriculum Vitae Personal Details Date of Birth: 8 January 1940 Family: Married (to Barbara Pearse); one daughter (Nicola) and one son

12 Mar 2024: The brain works as an integrated whole. Animals interact with the world by combining inputs from their senses of vision, hearing, smell, taste, touch and

2 Apr 2024: Search this website. Rising Talent Fellowship. The MRC Laboratory of Molecular Biology (LMB) is proud to launch a new three-year fully funded postdoctoral fellowship for scientists from Black heritage backgrounds. ... This Fellowship is a three-year

23 Feb 2024: Precise chromosome replication is essential for maintaining genome stability, yet the process itself is inherently risky. Duplex DNA must be transiently

5 Mar 2024: Molecular motors have critical roles in the trafficking of organelles, vesicles and macromolecules within the cytoplasm, and aberrant motor function is

23 Feb 2024: Cells are highly compartmentalized into numerous membrane-bound organelles. The membranes that define each organelle contain unique sets of embedded

21 Jul 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Emeritus.

24 Oct 2023: Joan A. Steitz Postdoc Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion

14 Mar 2024: In an effort to better understand human brain development, we have developed a new model system, called cerebral organoids.

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Chris Tate

18 Mar 2024: Ultimately, mycobacteria can cause granuloma breakdown by inducing programmed macrophage death, a step that further increases bacterial growth and promotes transmission to new hosts. ... Our findings have been borne out in humans and are informing new

23 Feb 2024: Science News : Scientists have mapped an insect brain in greater detail than ever before. ... Sky News : First map of insect brain signals 'big step forward' in understanding thoughts.

22 Mar 2024: Thus, understanding their cell biology requires re-thinking some of our most basic assumptions (bilayers membranes) and the development of new research tools and methods (high-temperature live cell imaging).

21 Jul 2023: Current Vacancies Listed below are the vacancies currently being advertised. In addition we welcome speculative applications from postdocs – see Postdoc

23 Feb 2024: Information transfer in the nervous system occurs at synapses, where presynaptic signals are interpreted by postsynaptic receptors. We study this process

24 Oct 2023: Perutz Student Prize The Perutz Student Prize is awarded annually for outstanding work performed at LMB prior to the award of a Ph.D. Nominees

21 Jul 2023: For a list of recent news items please see the LMB News section.

24 Oct 2023: Eileen Southgate Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion

21 Jul 2023: The LMB moved into a new, modern building in February 2013, on the Cambridge Biomedical Campus. ... A new type of immune cell, that can initiate allergic asthma, has been found.

29 Jan 2024: Dendritic cells (DCs) play a key role in initiation of cytotoxic immune responses against pathogens and tumours. In order to prime the relevant T cells,

23 Feb 2024: Our research is aimed at understanding the mechanisms and regulation of chromosome segregation in mitosis. During the cell cycle, accurate chromosome

21 Jul 2023: Since retirement in 2010 he has been working part-time in the University of Strathclyde on new types of microscope, using his ‘Mesolens’ and collaborating in published work on nonlinear optics

14 Mar 2024: Andrew Travers started his Ph.D. at the LMB under the tutelage of the late John Smith in 1964. After this he took a couple of years out as a post-doc in