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Radu Aricescu awarded the Karolinska Institutet 2023 Ulf von Euler…
https://www2.mrc-lmb.cam.ac.uk/radu-aricescu-awarded-the-karolinska-institutet-2023-ulf-von-euler-lectureship/12 Sep 2023: We are half way through a most exciting adventure, developing new technologies to understand the fundamental mechanisms of neurotransmission and to put this knowledge to good use.”.
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Biological Services Group - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/biological-services/21 Jul 2023: Biological Services Group The LMB Biological Services Group (BSG) maintains state-of-the-art facilities to house breeding and experimental colonies of
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Daniela Rhodes receives the 2023 WLA Prize in Life Science or…
https://www2.mrc-lmb.cam.ac.uk/daniela-rhodes-receives-the-2023-wla-prize-in-life-science-or-medicine/14 Sep 2023: Daniela Rhodes, Emeritus Scientist in the LMB’s Structural Studies Division, has been awarded the 2023 WLA Prize in Life Science or Medicine.
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A database to identify important genes of unknown function for…
https://www2.mrc-lmb.cam.ac.uk/a-database-to-identify-important-genes-of-unknown-function-for-analysis/9 Aug 2023: Despite decades of work, the role of thousands of human proteins remains unclear despite the likelihood that they participate in possibly new areas of biological function.
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Concordat on Openness in Animal Research - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/research/animal-research/concordat-on-openness-in-animal-research/21 Jul 2023: Concordat on Openness in Animal Research The Concordat on Openness is a declaration signed by many organisations involved with bioscience in the UK. The
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Dina Ratsimandresy’s journey from rural Madagascar to the LMB’s Light …
https://www2.mrc-lmb.cam.ac.uk/dina-ratsimandresys-journey-from-rural-madagascar-to-the-lmbs-light-microscopy-facility/15 Apr 2024: Stellenbosch University highlights Dina Ratsimandresy’s career so far – from studying Mathematics in Madagascar and postgraduate studies in South Africa
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Katja Röper: Development of tubular organs - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/katja-roper-development-of-tubular-organs/21 Jul 2023: I would find it very boring and unproductive if I was so competitive that I felt I had to restrict my lab from talking about new data at meetings.”. ... There’s a new group leaders’ group that meets monthly for lunch and presentations, and the
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Stephen Wallace wins Norman Heatley Award from Royal Society of…
https://www2.mrc-lmb.cam.ac.uk/stephen-wallace-wins-norman-heatley-award-from-royal-society-of-chemistry/21 Jun 2023: LMB 2012-2013, Career Development Fellow, PNAC The Royal Society of Chemistry has announced Stephen Wallace as the 2023 recipient of the Norman Heatley
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Image Processing Software - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/locally-developed-software/image-processing-software/21 Jul 2023: exe. For developing a new program, the following libraries might need to be invoked:.
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Job description and person specification template
https://www2.mrc-lmb.cam.ac.uk/wordpress/?wpdmdl=12061471 Feb 2024: To introduce and apply new techniques across a wide range of disciplines and to have the creativity and initiative to develop novel approaches and methods where required. ... moving into a new research discipline and/or needs to further develop their -
Cheaper microscope could bring protein mapping technique to the…
https://www2.mrc-lmb.cam.ac.uk/auto-draftcheaper-microscope-could-bring-protein-mapping-technique-to-the-massesauto-draft/7 Dec 2023: 7 December, 2023. A news piece in Science highlights how Chris Russo’s group and Richard Henderson, both in the LMB’s Structural Studies Division, have worked with other collaborators to ... build a new cryo–electron microscope at a fraction of
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LMB 365 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-365/21 Jul 2023: A great way to meet new people and relax after a busy day in the lab…. ... sites/nextgen/ that brought scientists from academia and industry together to discuss new developments.
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William Batey’s apprenticeship experience in the LMB’s Estates and…
https://www2.mrc-lmb.cam.ac.uk/william-bateys-apprenticeship-experience-in-the-lmbs-estates-and-facilities-department/24 Oct 2023: I surveyed the building, ordered new parts and installed new appliances.
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Raphin 1 and phosphatase inhibitors technology (2018) - MRC…
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/raphin1-2018/21 Jul 2023: Overall this new work identifies R15B as a druggable target for Huntington’s disease, and provides the first platform for target-based discovery of inhibitors of serine/threonine phosphatases. ... This novel approach may pave the way to a new
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Low energy cryo-EM to widen accessibility for fast and accurate…
https://www2.mrc-lmb.cam.ac.uk/low-energy-cryo-em-to-widen-accessibility-for-fast-and-accurate-structure-determination/28 Nov 2023: This new electron microscope promises to significantly increase the accessibility of cryo-EM. ... A low-cost electron microscope maps proteins at speed, Nature News. Primary Sidebar.
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Trim-Away™ (2017) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/trim-away-2017/21 Jul 2023: Search this website. Trim-Away (2017). Trim-Away is a new technology, developed by Dean Clift, Melina Schuh and Leo James, for the rapid removal of specific proteins from cells through
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Repurposed DNA repair factors prevent expansions of ‘parasitic’…
https://www2.mrc-lmb.cam.ac.uk/repurposed-dna-repair-factors-prevent-expansions-of-parasitic-genomic-retrotransposons/14 Aug 2023: New research from Nazareno Bona and Gerry Crossan, in the LMB’s PNAC Division, has identified one of these protections against retrotransposons. ... a new site in the genome.
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Tracking the milestones of the genome sequencing revolution…
https://www2.mrc-lmb.cam.ac.uk/tracking-the-milestones-of-the-genome-sequencing-revolution-highlights-lmb-achievements/17 Nov 2023: In charting the milestones in the history of genome sequencing development, UKRI include LMB research as integral to the revolution in the field. Namely,
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Royal Society Summer Science Exhibitions - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/lmb-on-the-road/royal-society-summer-science-exhibitions/21 Jul 2023: Royal Society Summer Science Exhibitions Each year the Royal Society holds an annual summer science exhibition that showcases the most exciting
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Patrycja Kozik: From starry nights to immunology - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/patrycja-kozik-from-starry-nights-to-immunology/21 Jul 2023: without her family; after school, she then left the country entirely to attend the brand new Jacobs University Bremen as one of its first undergraduates. ... After Bremen, Patrycja moved to Cambridge to do a PhD with Margaret (Scottie) Robinson at the
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Pore-forming protein perforin-2 is critical to immune response by…
https://www2.mrc-lmb.cam.ac.uk/pore-forming-protein-perforin-2-is-critical-to-immune-response-by-dendritic-cells/23 Jun 2023: New research from Patrycja Kozik’s group in the LMB’s PNAC Division has discovered a new pathway of antigen transport from endosomes into the dendritic cytosol. ... This research has helped further understanding of the mechanisms behind T cell
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London International Youth Science Forum - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/supporting-education/london-international-youth-science-forum/21 Jul 2023: The London International Youth Science Forum (LIYSF) is a two-week residential course for students aged 16-21 who have a keen interest in studying
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ModelAngelo software expands cryo-EM toolkit with faster atomic model …
https://www2.mrc-lmb.cam.ac.uk/modelangelo-software-expands-cryo-em-toolkit-with-faster-atomic-model-building-and-identification-of-novel-proteins/16 Apr 2024: Published on. 16 April, 2024. New cryo-EM imaging software incorporates cutting-edge algorithms and neural networks to remedy a long-standing problem in structural biology and enables the identification of
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Circadian rhythms, fireflies, and tuberculosis research; the LMB at…
https://www2.mrc-lmb.cam.ac.uk/circadian-rhythms-fireflies-and-tuberculosis-research-the-lmb-at-the-cambridge-festival-2024/8 Apr 2024: LMB scientists showcased their research to hundreds at the Cambridge Festival, with a hands-on activity and an art piece about body clocks and a talk about tuberculosis.
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Past Winners - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/past-events/crystal-growing-competition/past-winners/21 Jul 2023: Winners of the 2013-2014 competition Pupils had five weeks to grow the best-looking crystal of Potash Alum that they could. Their crystals were submitted
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From bench to blockbuster: the story of HUMIRA® – best-selling drug…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-exhibitions/from-bench-to-blockbuster-the-story-of-humira-best-selling-drug-in-the-world/21 Jul 2023: It is now licensed as a treatment for a range of autoimmune diseases and scientists are still discovering new applications. ... Monoclonal antibody technology is behind one third of all new drugs introduced worldwide.
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Structure of γ-Tubulin Ring Complex provides insights into nucleation …
https://www2.mrc-lmb.cam.ac.uk/structure-of-%CE%B3-tubulin-ring-complex-provides-insights-into-nucleation-process-behind-microtubule-formation/15 Apr 2024: An improved knowledge of the process of spindle formation at a molecular level will help to identify new targets for such drugs.
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TDP-43 forms amyloid filaments with distinct folds in different…
https://www2.mrc-lmb.cam.ac.uk/tdp-43-forms-amyloid-filaments-with-distinct-folds-in-different-neurodegenerative-conditions/2 Aug 2023: Published on. 2 August, 2023. Cryo-EM reveals that TDP-43 forms amyloid filaments with a new fold in the most common type of frontotemporal lobar degeneration. ... New research from Benjamin Ryskeldi-Falcon’s group in the LMB’s Neurobiology Division
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I'm a scientist, get me out of here! - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/supporting-education/im-a-scientist-get-me-out-of-here/21 Jul 2023: I'm a Scientist, Get Me Out Of Here is an online public engagement event during which scientists talk with school students from all over the UK and answer
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Centre for Chemical and Synthetic Biology - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/research/protein-and-nucleic-acid-chemistry/centre-for-chemical-and-synthetic-biology/21 Jul 2023: Search this website. Centre for Chemical and Synthetic Biology. Work in the Centre for Chemical and Synthetic Biology (CCSB) aims to develop new approaches to understanding biology at the molecular level, ... both in vitro and in living organisms, and to
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Neonatal Mouse Anaesthetisation Mould Request Form - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/neonatal-mouse-anaesthetisation-mould-request-form/21 Jul 2023: Neonatal Mouse Anaesthetisation Mould Request Form Researchers from Dr Ingo Greger’s laboratory at the MRC Laboratory of Molecular Biology have designed a
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MRC Lab Visits - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/past-events/crystal-growing-competition/mrc-lab-visits/21 Jul 2023: Schools Visits to the LMB Winning schools were invited to bring students to visit the MRC Laboratory of Molecular Biology in Cambridge for a half-day of
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Mesolens Microscopy (2009) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/mesolens-microscopy-2009/21 Jul 2023: As well as being faster, this new type of imaging can reach deeper into solid tissues, such as embryos or tumours. ... The technology has already opened up new possibilities: for macrophotography in biomedical optics, in imaging neurones and mammalian
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LMB Rising Talent Fellowship Additional Information 1. Is the ...
https://www2.mrc-lmb.cam.ac.uk/wordpress/?wpdmdl=12060822 Feb 2024: This Fellowship is for scientists who have a PhD in a relevant subject (or are due to complete PhD within 6 months), are moving into a new research discipline or have ... Postdoc induction and buddy system for new starters A postdoc buddy is a fellow -
How flies use smell to determine the identity and position of other…
https://www2.mrc-lmb.cam.ac.uk/how-flies-use-smell-to-determine-the-identity-and-position-of-other-flies/25 May 2023: Researchers from Greg Jefferis’ group in the LMB’s Neurobiology Division have determined the highly specified neural mechanisms which allow Drosophila flies to identify and locate males by scent of a pheromone.
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1 CURRICULUM VITAE Venki Ramakrishnan Nationality U.S.A. (since 1985) …
https://www2.mrc-lmb.cam.ac.uk/groups/ribo/download/ramakrishnan_cv_brief.pdf4 Jan 2024: The New Science of Aging and the Quest for Immortality 2024: Hodder and Stoughton (UK); William Morrow/HarperCollins (USA) SCIENTIFIC PUBLICATIONS Can be looked up through -
The Coot FAQ
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/coot-faq.html5 Sep 2023: This is what I do in such a case: first delete the residue, then add a new one with "Add Terminal Residue." then "Mutate -> Auto Fit." to the required type, then -
Scott Wilson competes on ‘Super Brain’ game show in front of hundreds …
https://www2.mrc-lmb.cam.ac.uk/scott-wilson-competes-on-super-brain-game-show-in-front-of-hundreds-of-millions-of-viewers/1 Mar 2024: Scott Wilson, PhD student in Albert Cardona’s group in the LMB’s Neurobiology Division, recently appeared on the popular Chinese game show ‘Super Brain’.
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Behind the scenes: Stephen Holmes and a surprising career switch to…
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-stephen-holmes/15 Dec 2023: In 2005 he joined the MRC as a User Briefing Coordinator, and was involved in the mammoth job of overseeing design, construction and delivery of the new LMB building, which was ... I turned up on my first day in the new role wearing a shirt and tie – I
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Crystallisation and X-ray - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/crystallisation-and-x-ray/21 Jul 2023: Crystallisation and X-ray A high quality crystal will amplify the reflections of an intense, monochromatic, beam of light. The resulting diffraction
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From the scientist’s view: a conversation with… Buzz Baum - MRC…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/from-the-scientists-view-a-conversation-with-buzz-baum/15 Dec 2023: with a new way of thinking about how origin of complex cells arose? ... that because we know nothing, we can ask those simple questions again and make new answers.
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Andrew Carter on dynein discoveries, his career so far, and pursuits…
https://www2.mrc-lmb.cam.ac.uk/andrew-carter-on-dynein-discoveries-his-career-so-far-and-pursuits-away-from-research/10 May 2023: Following his award of the Hooke Medal from the British Society of Cell Biology, Andrew Carter, Group Leader in the LMB’s Structural Studies Division, has
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Wanda Kukulski: Unlocking the secrets of membrane biology - MRC…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/wanda-kukulski-unlocking-the-secrets-of-membrane-biology/21 Jul 2023: Correlative light and electron microscopy is a relatively new technique, and especially when combined with electron cryo-tomography, what you can see is spectacular: “It’s like watching wildlife channels”, Wanda
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Paula da Fonseca: Deciphering the secrets of the proteasome - MRC…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/paula-da-fonseca-deciphering-the-secrets-of-the-proteasome/21 Jul 2023: for the development of new medicines, still in collaboration with Ed Morris, who happily, is now her collaborator in life as well as in the lab. ... In the light of the increase in drug-resistant malarial strains, such new weapons are vital for the fight
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Understanding the protein modifications behind Trim-Away protein…
https://www2.mrc-lmb.cam.ac.uk/understanding-the-protein-modifications-behind-trim-away-protein-degradation-technology/17 Apr 2023: Leo James’ group, in the LMB’s PNAC Division, has identified surprising protein modifications that underly Trim-Away protein degradation technology, which may explain its broad applicability to degrade almost any cellular protein.
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Cryo-EM structures reveal the unexpected ability of shelterin to…
https://www2.mrc-lmb.cam.ac.uk/cryo-em-structures-reveal-the-unexpected-ability-of-shelterin-to-modulate-telomeric-nucleosomes/29 Aug 2023: Instead, the new structures illustrate for the first time that TRF1 not only interacts with the nucleosomal DNA, but also with the core histone proteins. ... diseases. This new insight into how shelterin and nucleosomes interact will be crucial for
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LMB Lecture on John Kendrew’s personal and scientific life to be…
https://www2.mrc-lmb.cam.ac.uk/lmb-lecture-on-john-kendrews-personal-and-scientific-life-to-be-given-by-paul-wassarman/2 May 2023: Paul Wasserman will present his LMB Lecture on ‘The Extraordinary Life and Legacy of Sir John C. Kendrew’ at 4:00PM on Tuesday 9th May.
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Akaash Kumar receives PhD Student Award from Cambridge Society for…
https://www2.mrc-lmb.cam.ac.uk/akaash-kumar-receives-phd-student-award-from-cambridge-society-for-the-application-of-research/28 Apr 2023: His new system has been designed to be compatible with any camera-based fluorescence microscope, to maximise its use by other researchers to address their own scientific problems. ... I hope the technology developed during my PhD will benefit scientists
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From the scientist’s view: a conversation with… Patrycja Kozik - MRC…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/from-the-scientists-view-a-conversation-with-patrycja-kozik/15 Dec 2023: quite a lot of time to develop a new assay in order to study this process.
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Sarah Teichmann elected as Professor in Stem Cell Medicine at the…
https://www2.mrc-lmb.cam.ac.uk/sarah-teichmann-elected-as-professor-in-stem-cell-medicine-at-the-cambridge-stem-cell-institute/24 Oct 2023: Sarah Teichmann and her group will join the Cambridge Stem Cell Institute, where they will continue studying the composition of many human tissues in both
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