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  2. Structure of the endosomal Vps34 complex II reveals insights into its …

    https://www2.mrc-lmb.cam.ac.uk/structure-of-the-endosomal-vps34-complex-ii-reveals-insights-into-its-function/
    Thumbnail for Structure of the endosomal Vps34 complex II reveals insights into its function - MRC Laboratory of Molecular Biology 9 Oct 2015: The structure of the Vps34 complex may facilitate new approaches to developing both inhibitors and activators of autophagy.
  3. Sjors Scheres awarded the Royal Netherlands Chemical Society (KNCV)…

    https://www2.mrc-lmb.cam.ac.uk/sjors-scheres-awarded-the-royal-netherlands-chemical-society-kncv-gold-medal/
    Thumbnail for Sjors Scheres awarded the Royal Netherlands Chemical Society (KNCV) Gold Medal - MRC Laboratory of Molecular Biology 24 Sep 2015: Sjors Scheres, LMB group leader, awarded the Royal Netherlands Chemical Society Gold Medal. The KNCV Gold Medal is the highest Dutch award for Chemistry.
  4. Monoclonal antibodies: the invisible allies that changed the face of…

    https://www2.mrc-lmb.cam.ac.uk/monoclonal-antibodies-the-invisible-allies-that-changed-the-face-of-medicine/
    Thumbnail for Monoclonal antibodies: the invisible allies that changed the face of medicine - MRC Laboratory of Molecular Biology 11 Aug 2015: They are tiny magic bullets that are quietly shaping the lives of millions of patients around the world. Monoclonal antibodies are contained in six out of
  5. LMB receive highly commended prize at Understanding Animal Research…

    https://www2.mrc-lmb.cam.ac.uk/lmb-receive-highly-commended-prize-at-understanding-animal-research-openness-awards/
    Thumbnail for LMB receive highly commended prize at Understanding Animal Research Openness Awards - MRC Laboratory of Molecular Biology 11 Dec 2015: Representatives from across the UK life science community joined Understanding Animal Research at the Wellcome Collection in London recently to celebrate
  6. DNA sculpture from CRUK Art Trail finds home in Francis Crick’s…

    https://www2.mrc-lmb.cam.ac.uk/dna-sculpture-from-cruk-art-trail-finds-home-in-francis-cricks-former-laboratory/
    Thumbnail for DNA sculpture from CRUK Art Trail finds home in Francis Crick’s former Laboratory - MRC Laboratory of Molecular Biology 10 Nov 2015: During the summer of 2015 Cancer Research UK launched a DNA inspired art trail across London with a series of 21 DNA double helix sculptures. They invited
  7. David Komander part of collaborative consortium in the field of…

    https://www2.mrc-lmb.cam.ac.uk/david-komander-part-of-collaborative-consortium-in-the-field-of-deubiquitinating-enzymes/
    Thumbnail for David Komander part of collaborative consortium in the field of deubiquitinating enzymes. - MRC Laboratory of Molecular Biology 26 Mar 2015: Published on. 26 March, 2015. FORMA Therapeutics and Cancer Research Technology, Ltd (CRT) have announced the formation of two new virtual Asset Discovery and Development Companies (ADDCos) to represent the collective
  8. Atomic resolution of gamma-secretase – another milestone for…

    https://www2.mrc-lmb.cam.ac.uk/atomic-resolution-of-gamma-secretase-another-milestone-for-structure-determination-by-cryo-em/
    Thumbnail for Atomic resolution of gamma-secretase – another milestone for structure determination by cryo-EM - MRC Laboratory of Molecular Biology 17 Aug 2015: The atomic structure of the 170 kDa membrane protein gamma-secretase, a membrane protein complex that has an important role in Alzheimer’s disease, has
  9. Detecting and signalling DNA single-strand breaks: understanding the…

    https://www2.mrc-lmb.cam.ac.uk/detecting-and-signalling-dna-single-strand-breaks-understanding-the-mechanisms-of-dna-damage-recognition/
    Thumbnail for Detecting and signalling DNA single-strand breaks: understanding the mechanisms of DNA damage recognition - MRC Laboratory of Molecular Biology 26 Nov 2015: DNA damage represents a constant threat to the integrity of genomic information in cells and is closely linked to the origins of cancer. 
  10. tutorial-embo.dvi

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/tutorial-embo.pdf
    8 Sep 2015: Coot displays a Map Colour Selection window]. • Choose a new colour by clicking on the colour widgets. ... Coot adds intermediate white atoms and pops up a dialog]. • Accept the new atoms.
  11. Crystal Screen Lite™ is a complete reagent kit designed ...

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB06b.pdf
    26 Jun 2015: Discard the pipet tip, add a new pipet tip and pipet 1 ml of Crystal Screen Lite reagent 2 into reservoir A2.
  12. Cover MRC Case Studies FAW09

    https://www2.mrc-lmb.cam.ac.uk/archive/articles/Reviewing_translation_at_the_MRC.pdf
    15 Apr 2015: MRC science needs to be effectively translated into powerful new therapies, diagnostics, devices, and research tools. ... then for investigating other potential protein modifications. The technology will help produce new protein reagents that.
  13. Zooming in on molecular motors

    https://www2.mrc-lmb.cam.ac.uk/groups/cartera-jmol/jmol/ZoomOnDynein.html
    11 Jul 2015: The body breaks proteins down into their individual building blocks, called "amino acids" and then uses the amino acids to build new proteins like dynein.
  14. Using Coot for model building into EM maps:A tutorial ...

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/EM-Tutorial-Coot-PE.pdf
    8 Sep 2015: Each new top score is highlighted () and the coordinates are updated to the final highest score.
  15. KWRM_A_992668_O

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-3.pdf
    20 Oct 2015: Engineering new synaptic connections in the C.elegans connectome. Ithai Rabinowitch & William R Schafer. ... 3B, right), presumablydue to negative charge flowing fromAWC into AIY through the new electricalsynapse (Fig.
  16. tutorial.dvi

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/tutorial-embo.pdf
    27 Aug 2015: Coot displays a Map Colour Selection window]. • Choose a new colour by clicking on the colour widgets. ... We want a CYS:. • Mutate & Auto Fit. • Click on an atom in the new ALA.
  17. Paul EmsleyMRC Laboratory of Molecular Biology, Cambridge, UKJune…

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/Ligands-July-2015-v2.pdf
    16 Jul 2015: wwPDB Ligands. Year on year increase in the number of new entities. ... 6943 new ligand types (88%) are non-polymers. – LINKed ligands excluded.
  18. Changes in Postural Syntax Characterize Sensory Modulation and…

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-5.pdf
    14 Aug 2015: New imaging technology has made it possible to record neural activity from the majority ofC. ... 2. Lehner PN. Handbook of ethological methods. 2nd ed. Cambridge ; New York: Cambridge UniversityPress; 1996.
  19. httDownloaded from rsif.royalsocietypublishing.org ResearchCite this…

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-1.pdf
    4 Feb 2015: New York, NY 10032, USA.}Present address: Department of Biochemistry. and Biophysics, University of California,. ... New York, NY 10010, USA. Electronic supplementary material is available. at http://dx.doi.org/10.1098/rsif.2014.0963 or.
  20. Sensory Neurons Arouse C. elegans Locomotion via Both Glutamate and…

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-4.pdf
    30 Jun 2015: RESEARCH ARTICLE. Sensory Neurons Arouse C. elegansLocomotion via Both Glutamate andNeuropeptide ReleaseSeungwon Choi1,2,3, Kelsey P. Taylor1,2,3, Marios Chatzigeorgiou4, Zhitao Hu1,2,William R. Schafer4, Joshua M. Kaplan1,2,3. 1 Department of
  21. Reconstitution of a prokaryotic minus end-trackingsystem using TubRC…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2015-Fink-E1845-50.pdf
    27 Apr 2015: Clearly, new TubZ monomers incorporated only at thefilament ends that were free of TubRC (Fig. ... pH 7.5), 500 mM KCl, 10 mM EDTA, 0.5 mM TCEP] by chitin-affinity chromatography (New England Biolabs).

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