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23 Feb 2024: The machines that comprise this proteostasis network include the ribosome, which synthesizes new proteins, chaperones that help new proteins fold, and degradation factors that eliminate incorrect or damaged proteins. ... We expect that our results will

6 Sep 2012: New insight into common mutations in human cancers. Published on. 6 September, 2012. ... succeeded in providing new insights into how mutations of the PIK3CA affect its function.

13 Mar 2024: We also aim to use DMS to develop new force fields at different scales, such as implicit solvent or coarse-grained models, allowing larger systems to be simulated.

20 May 2024: In 2012 a new chemistry-oriented Centre for Chemical and Synthetic Biology (CCSB) was established, to help support the Division’s work in synthetic biology and strengthen its chemical expertise.

25 Mar 2024: Projects Main applications for October 2024 are now closed. The LMB exceptionally considers applications for research-only MPhil students provided they

26 Feb 2021: Linda Amos, former Group Leader in the LMB’s Structural Studies Division, died on Sunday 21st February 2021. Linda was an excellent electron microscopist, at the forefront of image analysis and reconstruction.

Search this website. LMB News. ... Bicycle Therapeutics has developed a new novel technology platform using phage display to select peptidic sequences that are cyclized on a chemical core.

Search this website. LMB News. ... The award was made in recognition of Jason’s “pioneering work on genetically encoding the synthesis of novel polymers in cells through development of methods to incorporate, for example, new amino

23 Feb 2024: Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD) and Amyotrophic Lateral Sclerosis (ALS)

25 Aug 2023: Since the orthogonal ribosome, unlike the natural ribosome, is not essential it is possible to evolve the orthogonal ribosome to read new genetic codes on the orthogonal message. ... This parallel translation pathway provides a series of blank codons

3 Mar 2010: Search this website. Potential new target for Asthma treatment discovered. Potential new target for Asthma treatment discovered. ... It is not often that that someone identifies a new type of white cell in the blood.

10 Jan 2024: CryoEM at IUCrJ: a new era.

1 Feb 2016: Search this website. Cryo-EM sheds new light on the spliceosome activation process. ... Cryo-EM sheds new light on the spliceosome activation process. Published on.

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Search this website. LMB News.

21 Jul 2023: Photographs The LMB has an extensive collection of photographs and images, a selection of which can be viewed here by either browsing the collection or

16 May 2024: Each year, the Fellows of the Royal Society elect up to 85 new Fellows and up to 24 new Foreign Members. ... Alumna Ruth Lehmann joins them as a new Foreign Member of the Royal Society.

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Philipp

th. July at 4.00pm in the LMBu2019s Max Perutz Lecture Theatre.u00a0 The title of the lecture is u2018Innovation by evolution: bringing new chemistry to lifeu2019.u00a0 The event is ... insights, by repurposing diverse existing proteins and their

29 Sep 2021: Moreover, this method provides new ways for studying the similarities and differences between diseases. ... This new classification complements the previous clinical diagnostic and neuropathological approaches, and allows for the identification of new

10 May 2024: The contents of eukaryotic cells are organised and moved around by motor proteins running along the tracks that make up the cytoskeleton (microtubules and

7 Jun 2024: Prior to joining the LMB he founded a company, now situated on the Cambridge Science Park, to apply the Mogrify cell reprogramming technology for the creation of new therapeutics.

18 Nov 2011: New evidence of nuocyte involvement in allergic asthma. Published on. 18 November, 2011. ... This discovery is an important step in determining whether nuocytes could be a new drug target for asthma treatment.

16 Feb 2024: Elucidating the molecular details of this pathway was therefore paramount and had the potential to reveal new therapeutic targets for treating cancer.

21 Jul 2023: Mark S. Bretscher Curriculum Vitae Personal Details Date of Birth: 8 January 1940 Family: Married (to Barbara Pearse); one daughter (Nicola) and one son

2 May 2024: lmb.cam.ac.uk/groups/shahbazi/2024/05/02/new-publication-connecting-delamination-and-differentiation-during-gastrulation/ ... shahbazi/2020/09/23/new-publication-how-does-an-increase-in-cell-numbers-affect-mouse-embryo-development/#respond Wed, 23 Sep

Search this website. LMB News. ... Published on. 31 July, 2009. Two therapies with their roots in antibody technology developed in the LMB and the Scripps Research Institute have recently emerged as promising new drug candidates to

Published on. 28 June, 2024. Andrew McKenzie’s group, in the LMB’s PNAC Division, have applied a new screening system and synthetic Boolean logic gate circuits to offer unprecedented insights ... fast, accurate model building at atomic levels and

43","modified_gmt":"2015-08-12T10:41:43","slug":"lmb-welcomes-new-group-leaders-madeline-lancaster-and-liz-miller","status":"publish","type":"post","link":"https://www2.mrc-lmb.cam.ac.uk/ ... recent arrival of two new group leaders in the LMBu2019s Cell

12 Mar 2024: The brain works as an integrated whole. Animals interact with the world by combining inputs from their senses of vision, hearing, smell, taste, touch and

2 Apr 2024: Search this website. Rising Talent Fellowship. The MRC Laboratory of Molecular Biology (LMB) is proud to launch a new three-year fully funded postdoctoral fellowship for scientists from Black heritage backgrounds. ... This Fellowship is a three-year

23 Feb 2024: Precise chromosome replication is essential for maintaining genome stability, yet the process itself is inherently risky. Duplex DNA must be transiently

56","modified_gmt":"2020-07-20T15:29:56","slug":"a-new-directed-evolution-technique-to-unlock-the-potential-of-xnas","status":"publish","type":"post","link":"https://www2.mrc-lmb.cam.ac. ... uk/a-new-directed-evolution-technique-to-unlock-the-potential-of

1 Aug 2012: New Insight on General Mechanism Behind Gene Expression. Published on. 1 August, 2012. ... change. This work was supported by the Medical Research Council, by a Royal Thai Government Scholarship and a Mahidol University new researcher grant and Faculty

5 Mar 2024: Molecular motors have critical roles in the trafficking of organelles, vesicles and macromolecules within the cytoplasm, and aberrant motor function is

3 Jun 2024: One of the major tasks that the nervous system faces is that of linking perception to action. We perceive the world around us through our senses and we

28 Aug 2020: Chris began his scientific career studying microbiology at the University of Bristol, receiving his BSc in 1988 before joining Kiyoshi’s new group in the Structural Studies Division of the LMB. ... new insights into the molecular basis of

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25 Jan 2019: In 1971, he was recruited to the LMB by Max Perutz to set up and head a new Sub-Division of Peptide Chemistry. ... The aim was to research and develop new methods for the partial and total synthesis of peptides and proteins.

23 Feb 2024: Cells are highly compartmentalized into numerous membrane-bound organelles. The membranes that define each organelle contain unique sets of embedded

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15 Jul 2020: Search this website. The LMB welcomes Ana Tufegdzic Vidakovic as a new Group Leader. ... Published on. 15 July, 2020. Ana Vidakovic Tufegdzi. The LMB is delighted to announce Ana Tufegdzic Vidakovic as a new Group Leader in the PNAC Division, where she

3 Jun 2024: Pluripotent stem cells have the unique capacity to generate all the cell types of the organism. In the embryo, they undergo concomitant changes in shape

21 Jul 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Emeritus.

11 Feb 2016: Structural insight offers potential for new anti-malarial treatment. Published on. 11 February, 2016. . ... falciparum proteasome and used this information to design a new compound with promising anti-malarial properties.

have recently emerged as promising new drug candidates to treat lupus, a potentially fatal autoimmune disease, and anthrax, a pressing concern due to bioterrorism.

21 Feb 2020: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Site Map.

24 Oct 2023: Joan A. Steitz Postdoc Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion