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  2. Environmental and placental contributions to pregnancy and life-long…

    https://www.ubs.admin.cam.ac.uk/system/files/public/environmental_and_placental_contributions_to_pregnancy_and_life-long_health_non-technical_summary_redacted.pdf
    29 Apr 2024: activities including publications in magazines, news articles, blogs, and via twitter / social media feeds. ... We will perform pilot experiments, for e.g. to check the effectiveness of new therapies.
  3. Extrinsic regulation of haematopoietic stem and progenitor cells in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/extrinsic_regulation_of_haematopoietic_stem_and_progenitor_cells_in_health_disease_and_as_a_therape_1_redacted.pdf
    30 Apr 2024: However, the underlying reasons (which could offer new therapies) are only partially understood. ... might be doing regarding animal research and ensure our methods stay updated within the new refinements implemented by others.
  4. Generation and screening of companion animal therapeutics.…

    https://www.ubs.admin.cam.ac.uk/system/files/public/generation_and_screening_of_companion_animal_therapeutics._non-technical_summary_redacted.pdf
    30 Apr 2024: Monoclonal antibodies are expected to become a new standard of care in veterinary medicine. ... In order to predict protein structures and design new proteins, large language models (LLMs) are used.
  5. CNS Neuron-glia interactions, myelin plasticity, and regeneration, in …

    https://www.ubs.admin.cam.ac.uk/system/files/public/cns_neuron-glia_interactions_myelin_plasticity_and_regeneration_in_health_and_disease_non-techni_redacted.pdf
    30 Apr 2024: The outputs of this licence will likely result in a new information and publications of the following:. ... With this knowledge gained we can identify new testable pathways for augmenting regeneration.
  6. Biobehavioural basis of the individual vunerability to impulsive…

    https://www.ubs.admin.cam.ac.uk/system/files/public/biobehavioural_basis_of_the_individual_vulnerability_to_impulsivecompulsive_spectrum_disorders_redacted.pdf
    29 Apr 2024: Similarly, it would not be possible to develop new treatments for brain disorders without testing them in animal models first. ... Any new procedure, or combination of procedures, used under this project licence will systematically be previously
  7. Neural, physiological and behavioural mechanisms underlying cognition …

    https://www.ubs.admin.cam.ac.uk/system/files/public/neural_physiological_and_behavioural_mechanisms_underlying_cognition_and_emotion_non-technical_sum_redacted.pdf
    30 Apr 2024: We have chosen to work with a new world monkey, the common marmoset. ... When we embark on a new study we tend to start off with 2 lead animals in which we test out our hypothesis.
  8. Neuronal circuit mechanisms underlying cognitive memory judgements…

    https://www.ubs.admin.cam.ac.uk/system/files/public/neuronal_circuit_mechanisms_underlying_cognitive_memory_judgements_non-technical_summary_redacted.pdf
    30 Apr 2024: memory symptoms, guiding new treatment strategies as well as providing insight into the mechanisms by which current therapies have their efficacious actions. ... When I embark on a new study, I start off with 2 lead animals in.
  9. Concordat on Openness on Animal Research in the UKAnnual ...

    https://www.ubs.admin.cam.ac.uk/sites/www.ubs.admin.cam.ac.uk/files/concordat-on-openness-annual-report-2023.pdf
    15 Nov 2023: While work was inevitably restricted, signatories adapted to the new situation with a focus on online engagement. ... Several organisations felt that an additional visit or onsite presentation would be helpful to better inform new staff about the

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