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18 Dec 2020: Article looking at the varied long-term effects of Covid-19 and the clues that latest research offers into what might be causing all the symptoms –

12 Aug 2020: Do it at least once. Each time I took part I gained a new perspective on my work and a better understanding of why some school students are put off by

9 Sep 2020: To do this, Julia infected mammalian cells with influenza A virus, leading to production of new viruses. ... Influenza causes very large numbers of cases of severe disease and death every year and new flu strains can cause global pandemics.

5 Nov 2020: The importance of our brain is reflected in the measures evolved to protect it, including the skull and meninges. However, its immune defence has been less well understood. Menna Clatworthy’s group has now identified immune cells derived from the

16 Nov 2020: Elyse Fischer, a PhD student in David Barford’s group, receives the award for her work on the molecular mechanisms of chromosome segregation during cell division.

14 May 2020: Julian Gough and his group are crowdsourcing raw genomic data for a phenotype prediction study…

4 Aug 2020: I was thrilled to receive the news and extremely honoured that our work has been recognised in this way.”.

6 Mar 2020: Correlative light and electron microscopy is a relatively new technique, and especially when combined with electron cryo-tomography, what you can see is spectacular: “It’s like watching wildlife channels”, Wanda

24 Jan 2020: In long feature format, Science Magazine profiles structural biology scientists at the LMB, including Chris Russo and Nobel Prize winner Richard

4 Jun 2020: Sjors Scheres’ and Radu Aricescu’s groups have pushed the boundaries of cryo-EM, allowing the technique to detect individual atoms in a protein for the

5 Feb 2020: Thyroglobulin, the protein precursor to the thyroid hormones T3 and T4, is the only molecule in the human body that is modified by iodine, and the modification directly leads to the formation of the thyroid hormones in the thyroid gland. But the

26 Jun 2020: Sarah Caddy is interviewed about her work on COVID-19 during the pandemic and extending her work with Leo James’ group on how antibodies neutralise

16 Oct 2020: They found that the virus is able to infect and produce new virus inside ChP epithelial cells, but neurons and glia were not susceptible to infection. ... With the excellent support of my supervisor, Madeline Lancaster, and the expertise of Leo James’s

28 May 2020: New research from the groups of Michel Goedert and Sjors Scheres has revealed the first structures of α-synuclein filaments from human brain.

18 Aug 2020: John Briggs’ group, in the LMB’s Structural Studies Division, has led two new studies of the spike (S) protein that protrudes from the virus surface.

4 Dec 2020: This reveals a new mechanism of immune synergy between antibodies and T cells, which are often thought to work quite separately. ... Therefore, this work provides multiple new concepts that could be exploited in the development of treatments for and

29 May 2020: New Members in 2020 include musicians, historians, social scientists, and researchers in the mathematical, physical, and biological sciences.

22 Apr 2020: Hearing and touch depend on the ability of sensory neurons to be activated by a force, such as pressure or vibration from sound, and then pass information on to the brain. William Schafer’s group has identified some of the key proteins that make

18 Dec 2020: Alex Bates, who recently completed his PhD in Greg Jefferis’ group in the Neurobiology Division, was awarded the BNA Postgraduate prize for his work on

1 Sep 2020: illness, offering hope of new therapies for a range of devastating conditions, from Alzheimer’s disease to epilepsy.

25 Mar 2020: Kim, who is currently the Whitley Chair at the Department of Biochemistry, University of Oxford and a fellow of Trinity College, has made hugely valuable

21 Jan 2020: Piotr Szwedziak, a former PhD student and post-doctoral researcher in Jan Löwe’s group, has received an EMBO Installation Grant to establish an

28 Oct 2020: Published on. 28 October, 2020. Karen in the Lab. When the LMB Director, Jan Löwe, ran an internal video competition for staff and students to submit ideas for new films about ... I’ve always been interested in using our knowledge of biological

17 Jun 2020: Understanding minute structural differences in (G protein-coupled receptor) GPCR complexes could lead to the design of more efficacious drugs that have fewer side effects

18 May 2020: MRC LMB seeks DNA volunteers. Published on. 18 May, 2020. Cambridge Independent feature story on Julian Gough’s new phenotype prediction genome data study, which is also exploring whether DNA genotype

20 Oct 2020: Compare this maps with the original. You should find that the new (smooth) map is easier to understand. ... use the Display Manager to delete the first (mrc) map. Change the contour Step for the new Maps:.

2 Jan 2020: Proof-of-principle research led by Chris Russo showing that cryo-EM could be made 10 times cheaper is highlighted by the MRC. “Our goal is to make cryo-EM

3 Jul 2020: Nicholas Green is interviewed in the Cambridge Independent about John Sutherland’s group’s recent research suggesting that DNA and RNA building blocks

6 Aug 2020: Yanlan Mao, who did her PhD with Matthew Freeman’s group in the LMB’s Cell Biology Division, has been awarded the RMS Medal for Life Sciences in

11 Dec 2020: Published on. 11 December, 2020. A Nature News Feature about origin of life chemistry, including key work by John Sutherland’s group, and selection of the specific destination of a NASA

24 Nov 2020: Rebecca Taylor’s group has identified a signalling molecule that connects detection of a stressful environment by the nervous system with molecular defence mechanisms in other tissues and leads to changes in feeding behaviour and reproduction.

7 Jul 2020: Our daily cycle is controlled by a central clock known as the SCN, but it has been unclear how the network of cells that make up the SCN generate the properties that make it a strong clock. Michael Hastings’ group has identified a signalling axis

8 Jul 2020: To identify new treatments, scientists need a better understanding of the role played by different parts of the immune system in this disease. ... An improved understanding of the immune system in the gut and how to rebalance the

28 Aug 2020: The brain contains an enormous number of connections, known as synapses. Their loss is associated with many disorders. Radu Aricescu’s group and collaborators in Japan and Germany have designed a molecule that restores synapses in animal disease

11 Dec 2020: Gisela Otten, post-doctoral researcher in Felix Randow’s group in the LMB’s PNAC Division, talks to the Cambridge Independent about her route to joining

23 Jul 2020: Producing maps of how neurons connect with each other (connectomes) allows scientists to build and test theories of brain function. Greg Jefferis’ group have presented the first full map of olfactory, thermosensory, and hygrosensory projection

23 Oct 2020: I have also started working on a new project with Radu Aricescu and Jan Löwe to test new vaccine candidates. ... chip model to understand the immune response to Mycobacterium tuberculosis and develop new drug treatments.

7 Dec 2020: The LMB celebrated its latest book, Ahead of the Curve: Women Scientists at the MRC Laboratory of Molecular Biology by Kathleen Weston, with an online book launch of presentations from around the world.

30 Apr 2020: The National Academy of Sciences of the USA recognises distinguished and continuing achievements in original scientific research by election to membership

16 Dec 2020: Georgina Ferry reviews ‘Ahead of the Curve: Women scientists at the MRC Laboratory of Molecular Biology’ by Kathleen Weston. From sequencing to stardom -

23 Jan 2020: The neuronal gene Arc plays important roles in neural plasticity, learning and memory-related molecular processes and has been shown to mediate intercellular RNA transfer by forming viral-like capsids. John Briggs’ group has now solved the first

4 May 2020: to reproduce new double-stranded DNA. ... These processes are tightly coupled by the replisome complex to avoid stretches of exposed single-stranded DNA between the point of unwinding and the point of synthesis of new DNA.

13 May 2020: M Madan Babu’s group publishes a comprehensive model for the functional innovations of TBP.

13 Oct 2020: After hearing him talk in a new group leaders’ seminar series, Liz realised that her colleague Madan Babu, who works on intrinsically disordered proteins, could help her a lot in understanding ... The job I’ve given myself is to do preliminary

24 Mar 2020: Clare Sansom describes the history of spliceosome research and its importance, focusing on the work of Kiyoshi Nagai and his group. More...

30 Jan 2020: The Blavatnik Awards honour outstanding, innovative scientists at the early stages of their careers. Emmanuel has been recognised for his work on protein

21 Feb 2020: the arts and sciences are a really powerful way to reach new audiences.”.

14 Jul 2020: Each of our cells contains about two metres of DNA. To be able to store all of this, the DNA must be very tightly compacted. Jan Löwe’s group have produced the first atomic model of condensin, a complex known to have a role in compacting DNA into

15 Jun 2020: Septic shock is a common cause of death that can be triggered by LPS, a component of the outer membrane of some bacteria. Felix Randow’s group has shown how the immune response against cytosol-invading bacteria is activated by a signalling

12 May 2020: UK consortium of leading protein production laboratories provide protein reagents for SARS-CoV-2 research for free, in an Open Science initiative led by Wellcome and UKRI.