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Paul Dear (1962 – 2020) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/paul-dear-1962-2020/16 Mar 2020: Paul was most interested in developing new methods and technologies to improve research and information gathering, particularly in genomics. ... Paul’s main area of research was in genomics, particularly the development of new technologies and -
Atomic advance for cryo-EM - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/atomic-advance-for-cryo-em/21 Oct 2020: Nature doi:10.1038/s41586-020-2829-0. Nature News and Views: Cryo-electron microscopy reaches atomic resolution. ... Nature News article:Primary Sidebar. Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. -
Coronavirus: The Spike - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/coronavirus-the-spike/30 Nov 2020: Science Museum Group blog: Many COVID-19 drugs, vaccines and tests depend on ‘the spike’. Roger Highfield, Science Director, talks to John Briggs and -
Chris Oubridge (1966-2020) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/chris-oubridge-1966-2020/28 Aug 2020: Chris began his scientific career studying microbiology at the University of Bristol, receiving his BSc in 1988 before joining Kiyoshi’s new group in the Structural Studies Division of the LMB. ... new insights into the molecular basis of -
Schafer Lab Research
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/People_Lab_Page.html11 Jun 2020: wschafer[at]mrc-lmb.cam.ac.uk. Denise Walker - Research Scientist. Nationality: British. A central theme of my previous postdoctoral research has been to combine protein biochemistry with functional and behavioural assays,. to elucidate the role of -
Site Map - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/site-map/21 Feb 2020: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Site Map. -
How two proteins work together in DNA damage detection - MRC…
https://www2.mrc-lmb.cam.ac.uk/how-two-proteins-work-together-in-dna-damage-detection/7 Feb 2020: These new structures, and the concomitant increased understanding of how PARPs create the ADP-ribosylation that initiates DNA repair processes, could potentially lead to improvements in PARP inhibitor efficacy and novel -
Scientific collaboration to focus on search for new, improved…
https://www2.mrc-lmb.cam.ac.uk/scientific-collaboration-to-focus-on-search-for-new-improved-detectors-for-low-energy-cryo-em/11 Mar 2020: Scientific collaboration to focus on search for new, improved detectors for low energy cryo-EM. ... detector was essential to fully realise the potential of the new microscope design. -
How cells avoid and resolve ribosome traffic jams - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/how-cells-avoid-and-resolve-ribosome-traffic-jams/16 Jul 2020: Ribosome collisions along an mRNA ‘road’ relay a message to stop new ribosomes from entering while a tow truck clears the wreckage. ... To maximise efficiency, new ribosomes start translating an mRNA before previous ones have finished. -
A new layer of complexity in GPCR signalling could explain…
https://www2.mrc-lmb.cam.ac.uk/a-new-layer-of-complexity-in-gpcr-signalling-could-explain-differences-in-receptor-function-and-drug-response/5 Nov 2020: A new layer of complexity in GPCR signalling could explain differences in receptor function and drug response. ... Nature. Nature News & Views:Primary Sidebar. Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. -
Freedom of Information - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/freedom-of-information/21 Feb 2020: Freedom of Information (FoI) Act, Environmental Information Regulations and Data Protection Act 2018 The Freedom of Information Act 2000 and Environmental -
Coronavirus: how the virus works - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/coronavirus-how-the-virus-works/27 May 2020: Science Museum blog: The development of COVID-19 treatments, tests, drugs and vaccines will be accelerated by molecular understanding of the COVID-19 -
A novel tau fold in the neurodegenerative disease corticobasal…
https://www2.mrc-lmb.cam.ac.uk/a-novel-tau-fold-in-the-neurodegenerative-disease-corticobasal-degeneration/13 Feb 2020: These new structures also reveal the presence of additional molecules in a cavity within the filament. ... patients. Understanding how and why tau assembles into different disease-specific structures will also be beneficial for the development of new -
First structure of a fungal GPCR - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/first-structure-of-a-fungal-gpcr/2 Dec 2020: Design of new, improved drugs with fewer side-effects requires a fuller understanding of their structures. -
Championing non-aversive mouse handling - MRC Laboratory of Molecular …
https://www2.mrc-lmb.cam.ac.uk/championing-non-aversive-mouse-handling/14 Aug 2020: Rachel introduced the new handling methods in the room she worked in to begin with. ... The next challenge was to encourage the rest of the facility to adopt the new way of working. -
Marta Shahbazi wins 2019 3Rs prize for applying new in vitro models…
https://www2.mrc-lmb.cam.ac.uk/marta-shahbazi-wins-2019-3rs-prize-for-applying-new-in-vitro-models-to-study-early-embryo-development/12 Jun 2020: Search this website. Marta Shahbazi wins 2019 3Rs prize for applying new in vitro models to study early embryo development. ... Marta Shahbazi wins 2019 3Rs prize for applying new in vitro models to study early embryo development. -
How is the Fanconi Anaemia pathway activated to remove DNA lesions? - …
https://www2.mrc-lmb.cam.ac.uk/how-is-the-fanconi-anaemia-pathway-activated-to-remove-dna-lesions/17 Feb 2020: New study, led by Pablo Alcón and Shabih Shakeel in Lori Passmore’s group, in collaboration with KJ Patel in the PNAC Division, uncovers a unique molecular “clamp and pin” mechanism that activates the D2l complex, which then recruits enzymes -
Patrick Chitwood wins the Birnstiel Award - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/patrick-chitwood-wins-the-birnstiel-award/8 Oct 2020: to create membraneless organelles within cells that allow selective orthogonal protein translation, meaning that non-canonical amino acids can be used to introduce new functionalities into proteins made in that part -
Brain organoids with the potential to predict drug permeability - MRC …
https://www2.mrc-lmb.cam.ac.uk/brain-organoids-with-the-potential-to-predict-drug-permeability/12 Jun 2020: To study the development and function of the human ChP, including how CSF is made, Madeline’s group developed a new organoid model of this tissue. ... reduce the number of new drugs that fail in phase 1 clinical trials. -
Cell scientist to watch – Hayley Sharpe - MRC Laboratory of Molecular …
https://www2.mrc-lmb.cam.ac.uk/cell-scientist-to-watch-hayley-sharpe/8 Dec 2020: Hayley Sharpe, a former PhD student with Sean Munro’s group in the Cell Biology Division, is interviewed by the Journal of Cell Science about her career -
Is cryo-EM taking over structural biology? - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/is-cryo-em-taking-over-structural-biology/11 Feb 2020: Published on. 11 February, 2020. This news story in Nature maps the revolutionary technique’s eventful journey in the structural biology field since 2012-13. -
A simple, novel mechanism to safeguard the integrity of the human…
https://www2.mrc-lmb.cam.ac.uk/a-simple-novel-mechanism-to-safeguard-the-integrity-of-the-human-genome/21 Aug 2020: To provide a comprehensive analysis of all possible STR permutations, Pierre, working with Guillaume Guilbaud also from Julian’s group, developed a new high-throughput assay that allows measurement of DNA -
RNA Society Spotlight on Kelly Nguyen - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/rna-society-spotlight-on-kelly-nguyen/3 Jul 2020: This month’s RNA Society Spotlight has a feature on Kelly Nguyen, a Group Leader in the LMB’s Structural Studies Division. Kelly describes the -
Researchers in Vienna, including LMB PhD student Max Kellner, develop …
https://www2.mrc-lmb.cam.ac.uk/researchers-in-vienna-including-lmb-phd-student-max-kellner-develop-a-new-quick-and-easy-covid-19-test/25 Jun 2020: Search this website. Researchers in Vienna, including LMB PhD student Max Kellner, develop a new “quick and easy” COVID-19 test. ... Researchers in Vienna, including LMB PhD student Max Kellner, develop a new “quick and easy” COVID-19 test. -
LMB Band 6 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/animal-research/lmb-band-6/21 Feb 2020: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. LMB Band -
Katja Röper: Development of tubular organs - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/katja-roper-development-of-tubular-organs/6 Jul 2020: I would find it very boring and unproductive if I was so competitive that I felt I had to restrict my lab from talking about new data at meetings.”. ... There’s a new group leaders’ group that meets monthly for lunch and presentations, and the -
Lights, Crafts and Charity: Christmas at the LMB - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lights-crafts-and-charity-christmas-at-the-lmb/22 Dec 2020: Fred Chapman switches the LMB Christmas lights on. LMB Director, Jan Löwe, commented: “Thank you to all at the LMB who made these events happen and came up with new ways ... all sometime in the New Year. -
Ribosomal rescue in our mitochondria - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/ribosomal-rescue-in-our-mitochondria/27 Nov 2020: Mitochondrial ribosomes are different from those in the cytoplasm of human cells and little is known about their quality control. Venki Ramakrishnan’s group has discovered a novel pathway to rescue stalled mitoribosomes and determined structures -
Ampersand by Sam Shendi exhibited outside the LMB - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/ampersand-by-sam-shendi-exhibited-outside-the-lmb/12 Oct 2020: Ampersand by Sam Shendi. If you walk past the main entrance to the LMB, you’ll see we have a bold new sculpture standing proudly on the plinth outside the reception. ... Julian Gough, a Group Leader in the Structural Studies Division and one member of -
Sydney Brenner. 13 January 1927 – 5 April 2019 - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/sydney-brenner-13-january-1927-5-april-2019/3 Sep 2020: From modest beginnings Sydney became an extraordinarily influential and accomplished molecular biologist. His critical knowledge of, and insights into, -
William Schafer elected Fellow of Royal Society - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/william-schafer-elected-fellow-of-royal-society/29 Apr 2020: The 51 new Fellows, 10 Foreign Members and one Honorary Fellow have been selected for their outstanding contributions to scientific understanding. ... With discoveries ranging from the first planets outside our solar system, to the creation of the -
Kelly Nguyen honoured with Suffrage Science award - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/kelly-nguyen-honoured-with-suffrage-science-award/28 Aug 2020: Kelly Nguyen, group leader in the LMB’s Structural Studies Division, has been chosen to receive a Suffrage Science award along with ten fellow women scientists and science communicators who work in the life sciences. -
Claudia Bonfio wins the Dream Chemistry Award - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/claudia-bonfio-wins-the-dream-chemistry-award/17 Dec 2020: Claudia Bonfio, a MSCA Fellow in the PNAC Division, has won the 2020 Dream Chemistry Award for her dream project proposal, “Unlocking primitive chemical messages”. -
Student and postdoc prizes awarded for outstanding work - MRC…
https://www2.mrc-lmb.cam.ac.uk/student-and-postdoc-prizes-awarded-for-outstanding-work/27 Oct 2020: for the radiation-induced specimen movement that has plagued the field for decades, with the design and creation of a new all-gold grid design that completely eliminates movement. ... With the help of new hardware and software, he led work to achieve -
Engaging with the public while social distancing - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/engaging-with-the-public-while-social-distancing/14 Apr 2020: Throughout March, 28 MRC-funded scientists, including three from the LMB, took part in the Medical Research Zone of I’m a Scientist, Get Me Out of Here -
From metastasis to your favourite biscuit: connecting with school…
https://www2.mrc-lmb.cam.ac.uk/from-metastasis-to-your-favourite-biscuit-connecting-with-school-students-from-home/12 Aug 2020: Do it at least once. Each time I took part I gained a new perspective on my work and a better understanding of why some school students are put off by -
Patrycja Kozik: From starry nights to immunology - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/patrycja-kozik-from-starry-nights-to-immunology/19 May 2020: without her family; after school, she then left the country entirely to attend the brand new Jacobs University Bremen as one of its first undergraduates. ... After Bremen, Patrycja moved to Cambridge to do a PhD with Margaret (Scottie) Robinson at the -
Telling the tale of tangled tau in Alzheimer’s disease - MRC…
https://www2.mrc-lmb.cam.ac.uk/telling-the-tale-of-tangled-tau-in-alzheimers-disease/28 Sep 2020: The LMB Director, Jan Löwe, recently ran an internal video competition in which staff and students could submit ideas for new films about life and science at the LMB. ... Michel: “The most important benefit to emerge from this new work is the -
Max Perutz Lecture to be given by John Diffley - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/max-perutz-lecture-to-be-given-by-john-diffley/20 Feb 2020: John was born and raised in New York City. He obtained his B.A., M.S. ... and Ph.D. from New York University. He then worked as a postdoctoral fellow in Bruce Stillman’s laboratory at Cold Spring Harbor from 1984–1990, where he began working on -
Tanmay Bharat announced as EMBO Young Investigator - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/tanmay-bharat-announced-as-embo-young-investigator/1 Dec 2020: LMB Alumnus Tanmay Bharat is among 30 life science researchers within their first four years as group leaders to become EMBO Young Investigators. He joins -
Membrane characteristics tune enzyme activity - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/membrane-characteristics-tune-enzyme-activity/4 Aug 2020: Lipid membranes surround our cells and form the boundaries around compartments within them. Roger Williams’ group has now shown how membrane characteristics can tune the activities of protein complexes with important roles in autophagy and -
Chris Tate and Marta Zlatic elected to EMBO membership - MRC…
https://www2.mrc-lmb.cam.ac.uk/chris-tate-and-marta-zlatic-elected-to-embo-membership/7 Jul 2020: New members are elected annually, by the existing membership, in recognition of their contribution to scientific excellence. ... I am really excited about the new opportunities this will open for exciting interactions with outstanding scientists across -
César Milstein Lecture to be given by Elaine Fuchs - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/cesar-milstein-lecture-to-be-given-by-elaine-fuchs/21 Jan 2020: Elaine is currently the Rebecca C. Lancefield Professor of Mammalian Cell Biology and Development at the Rockefeller University, New York, USA. ... We use skin as a model to understand how the microenvironment impacts the stem cells and their behavior in -
Balancing an appropriate immune response in the gut - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/balancing-an-appropriate-immune-response-in-the-gut/8 Jul 2020: To identify new treatments, scientists need a better understanding of the role played by different parts of the immune system in this disease. ... An improved understanding of the immune system in the gut and how to rebalance the -
Sir Aaron Klug. 11 August 1926 – 20 November 2018 - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/sir-aaron-klug-11-august-1926-20-november-2018/23 Jan 2020: Aaron Klug made outstanding contributions to the development of structural molecular biology. An early interest in viruses prompted him to think deeply -
Eduroam - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/building-and-facilities/eduroam/21 Feb 2020: eduroam for visitors to the LMB The LMB offers eduroam using the SSID of eduroam using EAP-TLS with no IPv6 support. Visitors should have already -
Daffodils announce LMB staff's fundraising for Marie Curie - MRC…
https://www2.mrc-lmb.cam.ac.uk/daffodils-announce-lmb-staffs-fundraising-for-marie-curie/23 Mar 2020: Led by Freda Chapman at the LMB, our staff raised £695 for Marie Curie, a registered charitable organisation, which provides care and support to people with terminal illnesses and their families. -
The brain’s immune defence comes from your gut - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/the-brains-immune-defence-comes-from-your-gut/5 Nov 2020: The importance of our brain is reflected in the measures evolved to protect it, including the skull and meninges. However, its immune defence has been less well understood. Menna Clatworthy’s group has now identified immune cells derived from the -
Ruth Lehmann awarded Vilcek Prize in Biomedical Science - MRC…
https://www2.mrc-lmb.cam.ac.uk/ruth-lehmann-awarded-vilcek-prize-in-biomedical-science/26 Oct 2020: Ruth Lehmann, a former postdoctoral visitor with Michael Wilcox and Peter Lawrence in the LMB’s Cell Biology Division, has been awarded the 2021 Vilcek -
Studying the spike protein of SARS-CoV-2 - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/studying-the-spike-protein-of-sars-cov-2/18 Aug 2020: John Briggs’ group, in the LMB’s Structural Studies Division, has led two new studies of the spike (S) protein that protrudes from the virus surface.
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