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20 Jul 2016: 20 July, 2016. Researchers in Greg Jefferis’s group in the LMB’s Neurobiology Division have developed a new online tool to analyse images of neurons. ... NBLAST is already proving useful in fly brain research to identify neuron types, organize large

14 Dec 2016: New hypothesis for the formation of macropinocytic cups. Published on. 14 December, 2016. ... the USA and Robert Insall at the Beatson Institute in Glasgow, has resulted in the formation of a new hypothesis for how these cups form.

2 Sep 2016: Thus parental H3/4 tetramers are interspersed with newly synthesised H3/4. Most of the time, the old and new proteins are not mixed within the same nucleosome. ... In DT40 cells lacking Rev1, certain normally repressed genes containing G quadruplex DNA

13 Oct 2016: This has given unprecedented insight into the catalytic mechanism of a DUB and revealed a new mechanism of how ubiquitin chains can be cleaved. ... The new understanding of the catalytic process in deubiquitinases will become a key reference point for

24 Oct 2016: Search this website. New technologies enable systematic recoding of genomes. New technologies enable systematic recoding of genomes. ... Using these new techniques they attempted systematic recoding of the genomic sequence in an essential operon using

11 Feb 2016: Structural insight offers potential for new anti-malarial treatment. Published on. 11 February, 2016. . ... falciparum proteasome and used this information to design a new compound with promising anti-malarial properties.

1 Feb 2016: Search this website. Cryo-EM sheds new light on the spliceosome activation process. ... Cryo-EM sheds new light on the spliceosome activation process. Published on.

8 Dec 2016: Now researchers in the LMB’s Structural Studies and Cell Biology divisions have used electron cryomicroscopy (cryo-EM) to reveal new insights into these mechanisms. ... It is hoped that these new insights will enrich our understanding of the

26 Jul 2016: This has provided important mechanistic insights into RNA-based splicing catalysis. It has consolidated nearly three decades of biochemistry and genetics on the spliceosome and indicates new research directions to be

9 Mar 2016: She is also developing new methods with cryo-EM to help determine protein structure, including the development of new specimen grids made of pure gold, that improve the quality of

6 Jul 2016: The LMB’s Danielle Mersch and Nicola Smyllie along with other leading female scientists from the region took to their soapboxes on Saturday 2nd July in

4 Jan 2016: The new structure provides the first high resolution view of an open and functioning protein conducting channel. ... By comparing the new Sec61 structure to these previous structures, they have predicted a two-step mechanism for how the channel might be

1 Dec 2016: The LMB has continued its collaboration with the University Technical College Cambridge (UTCC), with students visiting as part of their microscopy

6 Sep 2016: Published on. 6 September, 2016. The ability of scientists to create changes in gene sequences has improved dramatically in recent years with the emergence of a new method, dubbed ‘CRISPR’. ... This new approach was inspired by work in rice, which

18 Mar 2016: 'Synthetic biology' is a scientific approach that seeks to answer fundamental questions in biology by reconstruction and modification of the molecules and

11 Mar 2016: In addition, AMPA receptors are drug targets and the new structure offers development to novel protein interfaces of the receptor.

7 Nov 2016: It gave me a new perspective to our work in the lab and I’m looking forward to next time!”.

23 Nov 2016: group working on new tissue culture methods.

15 Apr 2016: Target of Rapamycin (TOR) is a protein kinase that is essential in maintaining cellular homeostasis. In mammalian cells the enzyme occurs as two large

23 Mar 2016: As part of the Cambridge Science Festival, two of the LMB’s group leaders talked to the public about their research at the University Technical College