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AP2 adaptors for clathrin-mediated endocytosis: These are Cargo…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Adaptors/index.html26 Sep 2011: Classical adaptors: e.g. the AP2 adaptor complex. appendages). The hinge domains bind to clathrin terminal domains. AP1, AP3 and AP4 adaptors have similar subunit compositions and bind to different cargo and accessory proteins (see Adaptor table 1). -
New intracellular transport system discovered. - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/new-intracellular-transport-system-discovered/10 Oct 2011: Search this website. New intracellular transport system discovered. New intracellular transport system discovered. ... Thus, this new transport system is much more flexible than constricted movement along microtubules.
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New evidence of nuocyte involvement in allergic asthma - MRC…
https://www2.mrc-lmb.cam.ac.uk/new-evidence-of-nuocyte-involvement-in-allergic-asthma/18 Nov 2011: New evidence of nuocyte involvement in allergic asthma. Published on. 18 November, 2011. ... This discovery is an important step in determining whether nuocytes could be a new drug target for asthma treatment.
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Breakthrough in Fanconi Anaemia research. - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/breakthrough-in-fanconi-anaemia-research/10 Feb 2011: KJ’s group have discovered a new gene in the mouse FA pathway known as SLX4.
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Propagation of mutant SOD1 misfolding. - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/propagation-of-mutant-sod1-misfolding/23 Feb 2011: Amyotrophic lateral sclerosis (ALS) is caused by the progressive dysfunction of specific nerve cells that control muscle movement. It belongs to a group
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Leon Lagnado Receives Prestigious HFSP Award. - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/leon-lagnado-receives-prestigious-hfsp-award/13 May 2011: Leon Lagnado from the LMB’s Neurobiology Division has been awarded a Human Frontiers Science Program (HFSP) Grant. The HFSP is an international funding
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Link Between Ribosome Maturation and Cancer - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/link-between-ribosome-maturation-and-cancer/3 May 2011: They not only define the mechanism underlying a fundamental step in ribosome biogenesis, but also directly identify new approaches to treat the disease.
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Digitization of visual signals in the retina - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/digitization-of-visual-signals-in-the-retina/29 Jun 2011: Using the zebrafish as a model organism, Leon’s group have used new techniques developed in the lab to image the retina of live fish and monitor how the synaptic connections
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LMB scientists reconstruct ‘Nature’s first enzyme’. - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/lmb-scientists-reconstruct-natures-first-enzyme/8 Apr 2011: The origin of life is one of the great, unsolved mysteries of biology. In a quest to improve understanding of how life might have originally emerged, a
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A small molecule to correct protein folding defects. - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/a-small-molecule-to-correct-protein-folding-defects/10 Mar 2011: to design new drugs that could benefit a broad range of diseases.
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Three Royal Society Awards for LMB Scientists. - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/three-royal-society-awards-for-lmb-scientists/19 Jul 2011: The Royal Society recognizes excellence in science and technology through its medals, awards and prize lectures. Amongst the recently announced
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First X-ray crystal structure of dynein motor domain - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/first-x-ray-crystal-structure-of-dynein-motor-domain/4 Mar 2011: The research was carried out over the last seven years by Andrew Carter, a new group leader in LMB’s Structural Studies Division, and Carol Cho, a graduate student who worked ... C&EN news article:Primary Sidebar. Search. Search this website. 2024 MRC
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In vivo role for Fanconi Anaemia DNA repair pathway identified - MRC…
https://www2.mrc-lmb.cam.ac.uk/in-vivo-role-for-fanconi-anaemia-dna-repair-pathway-identified/7 Jul 2011: In a new study published in the journal Nature today, they also discovered a two-tier defence system in our cells that limits the threat of permanent genetic damage. ... This new knowledge transforms our view of precisely how excess alcohol causes damage
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Understanding how hormones activate G protein-coupled receptors. -…
https://www2.mrc-lmb.cam.ac.uk/understanding-how-hormones-activate-g-protein-coupled-receptors/25 Jan 2011: News & Views). – now at the Paul Scherrer Institut. Primary Sidebar.
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2011 César Milstein Lecture to be given by Tom Rapoport. - MRC…
https://www2.mrc-lmb.cam.ac.uk/inaugural-milstein-lecture-to-be-given-by-tom-rapoport/4 Apr 2011: Professor Tom Rapoport from the Department of Cell Biology, Harvard Medical School will give the inaugural Milstein Lecture on Thursday April 7th 2011 at
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Inaugural Francis Crick Lecture to be given by David Anderson. - MRC…
https://www2.mrc-lmb.cam.ac.uk/inaugural-francis-crick-lecture-to-be-given-by-david-anderson/5 Sep 2011: The application of genetically based tools for marking, mapping and manipulating specific populations of neurons, together with machine vision-based approaches for automated analysis of behavior, have opened up new opportunities
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Hijacking protein quality control to regulate cellular communication. …
https://www2.mrc-lmb.cam.ac.uk/hijacking-protein-quality-control-to-regulate-cellular-communication/1 Apr 2011: When the first multicellular organisms evolved, their cells needed to communicate with each other to control their growth and development. Matthew
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Dinolite instructions
https://www2.mrc-lmb.cam.ac.uk/microscopes4schools/downloads/dinolite_instructions.pdf6 Jun 2011: This information is also automatically saved. 3. To take a new image, place your mouse over anything other than an existing thumbnail. -
Endocytic Interactome: How Interactomes can help us design…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Interactomes/index.html26 Sep 2011: What is endophilin and how does it work. Research on the mechanism of endophilin in rapid vesicle endocytosis. Research on proteins involved in clathrin-coated vesicle formation. Research on membrane bending. Research on protein-lipid interactions. -
Clathrin-mediated endocytosis: Coated vesicle assembly. There are 3…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Endocytosis/CCVAssembly.html26 Sep 2011: Steps in CCV assembly and links to structures and information around clathrin-coated vesicle formation and other forms of vesicle budding
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