Search

28 Apr 2010: There are still questions about how the structure recognizes the very slight curvature of the polar membrane, but the new structural information greatly advances the discussion.

2 Aug 2010: The title. CopyrightAmerican Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005. ... This can becrucial in the design of new generations of Vps34inhibitors with improved specificity, solubility,and cellular

21 Oct 2010: The identificationof quadruple as well as double filaments posed a new question,however: Which filament is present in cells? ... Both formed filaments similar to those of native TubZ. We then reconstructed the new filaments in three dimensionsto reveal

2 Aug 2010: We devised a new expression and purification strategy by introducing a TEV protease. ... All propeller-shaped inhibitors create a new specificity pocket not present in the apo form of the enzyme.

17 Feb 2010: References. Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ,Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Terwilliger TC(2002) PHENIX: building new software for automated crystal-lographic ... Mol Microbiol 51:1321–1332. Gerdes K (2009)

14 Sep 2010: Filaments stabilized in this way continue to polymerize with the addition of new ParM subunits at both ParR–parC-capped ends, although the actual rate of elongation of an individual

20 May 2010: Corresponding authors. LW Hamoen, The Centre for Bacterial CellBiology, Medical Science New Building, Medical School, NewcastleUniversity, Richardson Road, Newcastle upon Tyne NE2 4AX, UK.Tel.: þ44 191 208 3240; Fax: þ44 ... These were then removed

20 Jul 2010: Journal of Molecular Biology, doi:10.1016/j.jmb.2010.06.030

2 Aug 2010: This conformational changelifts the phenylalanine residue of the DFG motif to disruptits interaction with helix αC, thereby creating a new hydro-phobic pocket deep behind the ATP-binding site that has ... For these inhibitors, a new pocket is formed

7 Apr 2010: Processes of membrane shaping belonging to the second classinclude transient distortions of the membrane continuity and re-connections of the membrane surface in a new way.

30 Apr 2010: Stable for at least 2 years.4. T7 or SP6 polymerase (New England Biolabs). ... chromatography resin, wash extensively with bufferscontaining the desired detergent, and elute in a buffer contain-ing this new detergent.

14 Dec 2010: predicted gene products on chromosome one, we attempt to find new molecules that. ... To. this end, the worm has proven invaluable in the identification of new molecules.

1 Dec 2010: The EMBO Journal, (2010). doi:10.1038/emboj.2010.315

4 Oct 2010: Roles of Amphipathic Helices and the Bin/Amphiphysin/Rvs(BAR) Domain of Endophilin in Membrane CurvatureGenerationSReceived for publication, March 26, 2010, and in revised form, April 16, 2010 Published, JBC Papers in Press, April 23, 2010, DOI

16 Feb 2010: To maximize the severity of the phenotype (if any) caused by CtmPrP, the new.

20 Nov 2010: This zippering explains how generation of aSNARE complex brings the membranes together, but doesnot explain the mechanism of membrane fusion per se [53].New results show that SNARE assembly tends to