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BOOK_30_1.book(gkf097.fm)
https://supfam.mrc-lmb.cam.ac.uk/SUPERFAMILY/articles/nar2002.pdf11 Dec 2001: the CATH (8) database but are much less extensive(http://www.biochem.ucl.ac.uk/bsm/cath_new/Gene3D). ... 1997) Gapped blast and psi-blast: a new generation of protein database search programs. -
BOOK_30_1.book(gkf097.fm)
https://supfam.mrc-lmb.cam.ac.uk/bioinformatics/people/julian_gough/publications/gough_nar_supfam_2002.pdf11 Dec 2001: the CATH (8) database but are much less extensive(http://www.biochem.ucl.ac.uk/bsm/cath_new/Gene3D). ... 1997) Gapped blast and psi-blast: a new generation of protein database search programs. -
PII: S0167-7799(01)01813-3
https://supfam.mrc-lmb.cam.ac.uk/bioinformatics/people/julian_gough/publications/sat_trendsbio_ecoli_2001.pdf29 Oct 2001: Recent studies havedescribed this evolutionary mechanismin detail and show how mutations inactive site residues produce new catalyticproperties for enzymes4–7. ... J. Mol. Biol. 311, 693–708. 3 Jensen, R.A. (1976) Enzyme recruitment inevolution of -
BIOINFORMATICS Vol. 1 no. 1 2001Pages 1–7 An Insight ...
https://supfam.mrc-lmb.cam.ac.uk/bioinformatics/people/julian_gough/publications/apic_bioinformatics_domains_2001.pdf3 May 2001: more complex proteins haveevolved by the creation of the new protein families, or therecombination of existing families. ... This implies that in cre-ating new functions, nature more frequently combines oldbuilding blocks than inventing new ones. -
Domain Combinations in Archaeal, Eubacterial and Eukaryotic Proteomes
https://supfam.mrc-lmb.cam.ac.uk/bioinformatics/people/julian_gough/publications/apic_jmb_domains_2001.pdf25 Jun 2001: The underlying assumption is that Aand B have the chance to reshufe each time thereis a new combinatorial context. ... This impliesthat in creating new functions, nature has, overtime, combined more common building blockswith each other than -
Assignment of Homology to Genome Sequences using a Library of Hidden…
https://supfam.mrc-lmb.cam.ac.uk/bioinformatics/people/julian_gough/publications/gough_jmb_supfam_2001.pdf26 Oct 2001: A new procedure is described fordetecting and correcting those errors that arise at the model-buildingstage of the procedure. ... As well as giving assignments that can be usedin new investigations into genomes, they providepotential new annotations. -
The Evolution and Structural Anatomy of the Small Molecule Metabolic…
https://supfam.mrc-lmb.cam.ac.uk/bioinformatics/people/julian_gough/publications/sat_jmb_ecoli_2001.pdf19 Aug 2001: 2001 Academic Press. 694 Evolution of Metabolic Pathways. active-site residues produce new catalytic proper-ties for enzymes and, hence, the formation of newpathways.8 11. ... Serialrecruitment would be expected if, for instance achunk of a chromosome,
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