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Environmental and placental contributions to pregnancy and life-long…
https://www.ubs.admin.cam.ac.uk/system/files/public/environmental_and_placental_contributions_to_pregnancy_and_life-long_health_non-technical_summary_redacted.pdf29 Apr 2024: activities including publications in magazines, news articles, blogs, and via twitter / social media feeds. ... We will perform pilot experiments, for e.g. to check the effectiveness of new therapies. -
Extrinsic regulation of haematopoietic stem and progenitor cells in…
https://www.ubs.admin.cam.ac.uk/system/files/public/extrinsic_regulation_of_haematopoietic_stem_and_progenitor_cells_in_health_disease_and_as_a_therape_1_redacted.pdf30 Apr 2024: However, the underlying reasons (which could offer new therapies) are only partially understood. ... might be doing regarding animal research and ensure our methods stay updated within the new refinements implemented by others. -
Generation and screening of companion animal therapeutics.…
https://www.ubs.admin.cam.ac.uk/system/files/public/generation_and_screening_of_companion_animal_therapeutics._non-technical_summary_redacted.pdf30 Apr 2024: Monoclonal antibodies are expected to become a new standard of care in veterinary medicine. ... In order to predict protein structures and design new proteins, large language models (LLMs) are used. -
CNS Neuron-glia interactions, myelin plasticity, and regeneration, in …
https://www.ubs.admin.cam.ac.uk/system/files/public/cns_neuron-glia_interactions_myelin_plasticity_and_regeneration_in_health_and_disease_non-techni_redacted.pdf30 Apr 2024: The outputs of this licence will likely result in a new information and publications of the following:. ... With this knowledge gained we can identify new testable pathways for augmenting regeneration. -
PPL number: | Granted: 11 Nov 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/mice_with_adaptive_human_immune_systems_and_their_application_for_drug_and_vaccine_discovery_nts_redacted.pdf19 Aug 2021: Why is it important to undertake this work? It is important to undertake this work so that we can discover new drugs and better vaccines for treating and preventing many different ... New medicines, namely vaccines and drugs. Drugs that offer potential -
Biobehavioural basis of the individual vunerability to impulsive…
https://www.ubs.admin.cam.ac.uk/system/files/public/biobehavioural_basis_of_the_individual_vulnerability_to_impulsivecompulsive_spectrum_disorders_redacted.pdf29 Apr 2024: Similarly, it would not be possible to develop new treatments for brain disorders without testing them in animal models first. ... Any new procedure, or combination of procedures, used under this project licence will systematically be previously -
University of Cambridge AWERB Handbook Version 6.6 2nd March ...
https://www.ubs.admin.cam.ac.uk/system/files/public/02.03.2021_awerb_handbook_6.6_external.pdf3 Mar 2021: from the AWERB Standing Committee to consider the 3Rs sections of some new project licence. ... where new or revisions are necessary to Standard Operating Procedures [SOPs] and implement University. -
Neural, physiological and behavioural mechanisms underlying cognition …
https://www.ubs.admin.cam.ac.uk/system/files/public/neural_physiological_and_behavioural_mechanisms_underlying_cognition_and_emotion_non-technical_sum_redacted.pdf30 Apr 2024: We have chosen to work with a new world monkey, the common marmoset. ... When we embark on a new study we tend to start off with 2 lead animals in which we test out our hypothesis. -
Neuronal circuit mechanisms underlying cognitive memory judgements…
https://www.ubs.admin.cam.ac.uk/system/files/public/neuronal_circuit_mechanisms_underlying_cognitive_memory_judgements_non-technical_summary_redacted.pdf30 Apr 2024: memory symptoms, guiding new treatment strategies as well as providing insight into the mechanisms by which current therapies have their efficacious actions. ... When I embark on a new study, I start off with 2 lead animals in. -
PPL number: | Granted: 12 Jun 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/biobehavioural_basis_of_vulnerability_to_impulsivecompulsive_spectrum_disorders_-_optimisation_and_redacted.pdf19 Aug 2021: Similarly, it would not be possible to develop new treatments for brain disorders without testing them in animal models first. ... Thus, our recent work on environmental enrichment has actually shed new light on the rather anthropomorphic view of the
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