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31 - 50 of 63 search results for news |u:www.ubs.admin.cam.ac.uk
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  2. PPL number: | Granted: 23 Oct 20 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/evaluation_of_novel_strategies_for_bone_repair_nts_redacted.pdf
    19 Aug 2021: These papers will describe the development of a new type of bone repair material. ... the structure may be compromised, while if it too slow it may adversely affect new bone formation.
  3. PPL number: | Granted: 22 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_germ_free_and_gnotobiotic_animals_service_licence_nts_redacted.pdf
    13 Sep 2021: In order to produce new mouse colonies a minority of germ-free mice will be given mammalian gut bacteria orally to produce gnotobiotic mice with a known gut flora (bacteria).
  4. PPL number: | Granted: 28 Jul 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/developing_anti-malarial_transmission_blocking_interventions_nts_redacted.pdf
    13 Sep 2021: What's the aim of this project? This project aims to discover and develop new ways to treat or prevent malaria transmission and disease. ... As such, the development of new anti-malaria blocking strategies is a major objective.
  5. PPL number: | Granted: 24 Sep 20 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_role_of_physical_cues_in_nervous_system_function_in_wild_type_and_transgenic_anima_redacted.pdf
    19 Aug 2021: The long-term goal of this research is to discover new mechanisms controlling the growth of nerve cells.
  6. PPL number: | Granted: 09 Sep 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_for_the_treatment_of_cancer_nts_redacted.pdf
    13 Sep 2021: The research will aid in the development of new bacterial therapies to treat cancer. ... We continuously consider their use and development in light of new experimental data.
  7. PPL number: | Granted: 05 May 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/safety_efficacy_and_immunogenicity_of_regenerative_cellular_therapies_redacted.pdf
    18 Jun 2021: This network will be utilised to maximise the dissemination of the new knowledge gained through this project. ... 3) By generating large quantities of human cells, where appropriate, we can continue to perform new studies using the same human cells.
  8. PPL number: | Granted: 25 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/circuit_mechanisms_of_learning_and_memory_in_the_mammalian_brain_nts_expires2026_redacted.pdf
    13 Sep 2021: The new insights gained could lead to new strategies for treating such disorders, including learning disabilities and Alzheimer's disease. ... Moreover, our institution's web pages provide regular updates on new developments in the 3Rs.
  9. PPL number: | Granted: 02 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_regulation_of_fat_mass_and_its_association_with_metabolic_disease_redacted.pdf
    18 Jun 2021: tolerance, providing new information on how the genes under investigation impact human metabolism and health. ... or 'negative' in the same way that a trial of a new treatment would be.
  10. PPL number: | Granted: 14 Jul 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_role_of_transposable_elements_in_cichlid_fish_development_and_evolution_nts_redacted.pdf
    13 Sep 2021: Our investigations and the data generated are expected to lead to new collaborations with other researchers. ... We will incorporate new recommendations on animal welfare, as soon as possible after their publication.
  11. PPL number: | Granted: 12 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/promoting_proliferation_in_non-regenerative_tissues_redacted.pdf
    18 Jun 2021: The work will;. 1. Provide new insights into the mechanisms required for regeneration. ... Thus, animal experiments are essential to understand regulatory mechanisms and to design and test potential new therapies.
  12. PPL number: | Granted: 30 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_mechanisms_involved_in_genome_regulation_nts_redacted.pdf
    13 Sep 2021: This second part will provide new hypotheses and research avenues for future research projects about mitochondrial and neurodegenerative diseases. ... Data generated from this project will form the basis for new funding applications, and may eventually
  13. PPL number: | Granted: 24 May 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_influencing_mammalian_digit_tip_regeneration_redacted.pdf
    18 Jun 2021: This project will likely result in new information and publications about the following:. ... In recent years scientists have developed a new way of growing (culturing) cells in 3 dimensions.
  14. PPL number: | Granted: 04 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_and_treatment_of_pulmonary_vascular_diseases_redacted.pdf
    18 Jun 2021: We aim to develop new approaches to treatment that target the pathways identified from human genetic studies. ... We will disseminate new knowledge and findings by publishing our results in internationally recognised scientific journals.
  15. PPL number: | Granted: 06 Jul 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_role_of_the_immune_system_in_cardiovascular_disease_nts_expires2026_redacted.pdf
    13 Sep 2021: However, our understanding of how this happens is still limited, and this has prevented scientists from finding new effective treatments. ... Our results will therefore benefit the scientific community through the provision of important new knowledge
  16. PPL number: | Granted: 02 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/ageing_and_therapy_in_mouse_models_for_neurodegenerative_diseases_redacted_0.pdf
    18 Jun 2021: We expect to test new compounds that inhibit alpha-synuclein aggregation into clumps and spreading to delay the development of pathology. ... Several collaborations are in place and will be developed to obtain new tools to further the understanding of
  17. PPL number: | Granted: 22 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/impact_of_sensory_and_electrical_activity_on_neuronal_function_nts_redacted.pdf
    13 Sep 2021: Chiefly, outputs will include generation of new knowledge, which will be timely and freely disseminated as publications in open-access journals, full datasets, and conference presentations. ... Before behavioural testing, mice will be acclimatised to the
  18. PPL number: | Granted: 04 Feb 20 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/tuberculosis_pathogenesis_treatment_in_zebrafish_and_medaka_nts_redacted.pdf
    19 Aug 2021: Animals from these new lines will be used to generate eggs by natural spawning. ... In the case of new chemicals, pilot experiments will be used to test chemical toxicity.
  19. PPL number: | Granted: 24 May 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_genetically_altered_animals_for_regenerative_neuroimmunology_research_redacted_0.pdf
    18 Jun 2021: We are using new-born mice to collect cells to grow and keep in a dish to do experiments. ... provide additional sources of new recommendations and advances in animal techniques and clinically applicable models.
  20. PPL number: | Granted: 09 Sep 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_integrated_stress_response_in_respiratory_disease_nts_redacted.pdf
    13 Sep 2021: All new information will be presented at scientific conferences and published as peer-reviewed research articles. ... When repeated or prolonged interventions are required, animals will be acclimitised to new environments (e.g.
  21. PPL number: | Granted: 10 Jun 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_diseases_with_an_inflammatory_component_nts_expires2022_redacted.pdf
    13 Sep 2021: Hence, there is an urgent need for new and safe drugs that successfully reverses or prevents progression of liver injury in patients with NASH. ... Page 4 of 7. By researching on new targets for such related diseases is a clear unmet clinical need.

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