Search

28 Oct 2020: Published on. 28 October, 2020. Karen in the Lab. When the LMB Director, Jan Löwe, ran an internal video competition for staff and students to submit ideas for new films about ... I’ve always been interested in using our knowledge of biological

26 Jun 2020: Sarah Caddy is interviewed about her work on COVID-19 during the pandemic and extending her work with Leo James’ group on how antibodies neutralise

29 May 2020: New Members in 2020 include musicians, historians, social scientists, and researchers in the mathematical, physical, and biological sciences.

18 Dec 2020: Alex Bates, who recently completed his PhD in Greg Jefferis’ group in the Neurobiology Division, was awarded the BNA Postgraduate prize for his work on

24 Nov 2020: Rebecca Taylor’s group has identified a signalling molecule that connects detection of a stressful environment by the nervous system with molecular defence mechanisms in other tissues and leads to changes in feeding behaviour and reproduction.

25 Mar 2020: Kim, who is currently the Whitley Chair at the Department of Biochemistry, University of Oxford and a fellow of Trinity College, has made hugely valuable

23 Jul 2020: Producing maps of how neurons connect with each other (connectomes) allows scientists to build and test theories of brain function. Greg Jefferis’ group have presented the first full map of olfactory, thermosensory, and hygrosensory projection

28 Aug 2020: The brain contains an enormous number of connections, known as synapses. Their loss is associated with many disorders. Radu Aricescu’s group and collaborators in Japan and Germany have designed a molecule that restores synapses in animal disease

23 Oct 2020: I have also started working on a new project with Radu Aricescu and Jan Löwe to test new vaccine candidates. ... chip model to understand the immune response to Mycobacterium tuberculosis and develop new drug treatments.

1 Sep 2020: illness, offering hope of new therapies for a range of devastating conditions, from Alzheimer’s disease to epilepsy.

21 Jan 2020: Piotr Szwedziak, a former PhD student and post-doctoral researcher in Jan Löwe’s group, has received an EMBO Installation Grant to establish an

18 May 2020: MRC LMB seeks DNA volunteers. Published on. 18 May, 2020. Cambridge Independent feature story on Julian Gough’s new phenotype prediction genome data study, which is also exploring whether DNA genotype

7 Dec 2020: The LMB celebrated its latest book, Ahead of the Curve: Women Scientists at the MRC Laboratory of Molecular Biology by Kathleen Weston, with an online book launch of presentations from around the world.

2 Jan 2020: Proof-of-principle research led by Chris Russo showing that cryo-EM could be made 10 times cheaper is highlighted by the MRC. “Our goal is to make cryo-EM

3 Jul 2020: Nicholas Green is interviewed in the Cambridge Independent about John Sutherland’s group’s recent research suggesting that DNA and RNA building blocks

6 Aug 2020: Yanlan Mao, who did her PhD with Matthew Freeman’s group in the LMB’s Cell Biology Division, has been awarded the RMS Medal for Life Sciences in

23 Jan 2020: The neuronal gene Arc plays important roles in neural plasticity, learning and memory-related molecular processes and has been shown to mediate intercellular RNA transfer by forming viral-like capsids. John Briggs’ group has now solved the first

11 Dec 2020: Published on. 11 December, 2020. A Nature News Feature about origin of life chemistry, including key work by John Sutherland’s group, and selection of the specific destination of a NASA

4 May 2020: to reproduce new double-stranded DNA. ... These processes are tightly coupled by the replisome complex to avoid stretches of exposed single-stranded DNA between the point of unwinding and the point of synthesis of new DNA.

13 Oct 2020: After hearing him talk in a new group leaders’ seminar series, Liz realised that her colleague Madan Babu, who works on intrinsically disordered proteins, could help her a lot in understanding ... The job I’ve given myself is to do preliminary

11 Dec 2020: Gisela Otten, post-doctoral researcher in Felix Randow’s group in the LMB’s PNAC Division, talks to the Cambridge Independent about her route to joining

13 May 2020: M Madan Babu’s group publishes a comprehensive model for the functional innovations of TBP.

30 Apr 2020: The National Academy of Sciences of the USA recognises distinguished and continuing achievements in original scientific research by election to membership

16 Dec 2020: Georgina Ferry reviews ‘Ahead of the Curve: Women scientists at the MRC Laboratory of Molecular Biology’ by Kathleen Weston. From sequencing to stardom -

11 Feb 2020: As a very new postdoc in Jürgen Knoblich’s lab in Vienna, she was trying to get mouse neural epithelial cells to form neural rosettes, but couldn’t get the cells ... LMB trusts me to think about these questions is great.” And she’s not felt

15 Jun 2020: Septic shock is a common cause of death that can be triggered by LPS, a component of the outer membrane of some bacteria. Felix Randow’s group has shown how the immune response against cytosol-invading bacteria is activated by a signalling

14 Jul 2020: Each of our cells contains about two metres of DNA. To be able to store all of this, the DNA must be very tightly compacted. Jan Löwe’s group have produced the first atomic model of condensin, a complex known to have a role in compacting DNA into

21 Feb 2020: the arts and sciences are a really powerful way to reach new audiences.”.

24 Mar 2020: Clare Sansom describes the history of spliceosome research and its importance, focusing on the work of Kiyoshi Nagai and his group. More...

30 Jan 2020: The Blavatnik Awards honour outstanding, innovative scientists at the early stages of their careers. Emmanuel has been recognised for his work on protein

12 May 2020: UK consortium of leading protein production laboratories provide protein reagents for SARS-CoV-2 research for free, in an Open Science initiative led by Wellcome and UKRI.

10 Nov 2020: Where does Cryo-EM Coot fit into the various builds/releases? What's new in 0.9 and how does it help? –

21 Feb 2020: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. LMB Band

28 Sep 2020: how depth is represented in 3D applications– problems with the current representation– Screenshots: how New Coot is an improvement on Old Coot. ... Ambient New Lighting Model:. – Ambient, Diffuse, Specular, Fresnel, Ambient Occlusion– Not yet:

13 Oct 2020: The Hippocrates Additive Screen is a new 48-condition additive screen, containing a library of unique drug-like compounds to enhance protein stability and crystallisability.

31 Jan 2020: HONOURS AND AWARDS: Apr 2018 Wellcome Investigator Award May 2016 EMBO Membership Dec 2012 Wellcome Trust New Investigator Award Nov 2012 EMBO Young Investigator Program Oct 2010 Elected Fellow of Clare ... Curriculum vitae. Other activities 2020

28 Feb 2020: Get one new zip lock bag per brain, and open them so that they are easy to handle with dirty hands later on. ... Put brain in new zip lock bag and wash in PBS.

28 Jul 2020: L. D. & Kirshner, D. A. (1971). Nature New Biol. 231,.

28 Jan 2020: After 3 hours or so, make a new dilution. Consider also spinning the 250 µL stock if background is still high.

8 Jun 2020: J. Begg, S. J. Dewar, W. D. Donachie, A new Escherichia coli cell division gene, ftsK. ... Nucleic Acids Res. 32, 5260–5279 (2004). 28. J. Zivanov et al., New tools for automated high-resolution cryo-EM structure de-termination in RELION-3.

31 Jan 2020: Struct. Biol. 180, 519–530 (2012). 35. Zivanov, J. et al. New tools for automated high-resolution cryo-EM structure determination in RELION-3.

14 Jul 2020: The phase before the stimulus is plotted against the difference between the new phase and the old phase. ... Phase transition curve: a curve describing the relationship between the circadian phase at which a stimulus is applied and the resultant new

15 Sep 2020: association with Smc1’s ATPase head and the coiled coil emerging from Smc3’s head creates a new.

12 Jun 2020: For correspondence:. rhegde@mrc-lmb.cam.ac.uk. †These authors contributed. equally to this work. Competing interest: See. page 25. Funding: See page 25. Received: 15 April 2020. Accepted: 26 May 2020. Published: 27 May 2020. Reviewing editor:

24 Jul 2020: For correspondence:. rhegde@mrc-lmb.cam.ac.uk. †These authors contributed. equally to this work. Competing interest: See. page 25. Funding: See page 25. Received: 15 June 2020. Accepted: 10 July 2020. Published: 13 July 2020. Reviewing editor: