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https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/49_MacKinnon_AL_JACS_2007.pdf30 May 2008: Supporting Information Available: Detailed experimental section,synthesis, and spectral characterization of new compounds. -
Asymmetric distribution of pause transfer sequences in apolipoprotein …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/6_Kivlen_MH_JLR_1997.pdf30 May 2008: Asymmetric distribution of pause transfer sequences in apolipoprotein B-I00. Maryann H. Kivlen, Cynthia A. Dorsey, Vishwanath R. Lingappa,'yt and Ramanujan S. Hegde Departments of Physiology and Medicine, University. of California, San Francisco, -
doi:10.1016/j.str.2008.05.003
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/52_Menetret_JF_Structure_2008.pdf22 Jul 2008: The new structure in-. dicates that a single copy of Sec61 is bound to the nontranslating. ... plexes bound to ribosomes. The TRAP ComplexOur new structure shows that one copy of the TRAP complex is. -
doi:10.1016/j.devcel.2008.06.015
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/54_Rane_NS_DevCell_2008.pdf18 Sep 2008: Clearly, new in situ methodologies for measuring translocation. will be needed to assess this effect of PrPSc on a finer scale. ... Figure 4D). Furthermore, steady-state Ifn-PrP expression levels. in whole brain, and even neurons cultured from transgenic -
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https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/vandenent2008ftsq.pdf4 Mar 2008: Structural and mutational analysis of the cell divisionprotein FtsQ. Fusinita van den Ent,1 Thessa M. F. Vinkenvleugel,2. Alice Ind,1 Philip West,1 Dmitry Veprintsev,1. Nanne Nanninga,2 Tanneke den Blaauwen2 andJan Löwe11MRC-LMB, Hills Road, -
Dissertation
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/AndyHuang.pdf6 Mar 2008: Here we use. xvi. automated methods to automatically detect these activities, which rely in part on a new method. ... These new. methods have made it possible to reliably detect events that are time-consuming and laborious to. -
doi:10.1016/j.molcel.2008.05.027
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsK%20MolCell%202008%20Lowe.pdf16 Aug 2008: The new. high-resolution structure confirms that FtsKg is a winged helix. ... conformation, though the new high-resolution crystal structure. shows that the two strands do not have a regular b sheet hydro-. -
GB-9-7-229-Amos_9.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/gb-2008-9-7-229.pdf4 Aug 2008: tubules with the aid of new microtubule-associated proteins. (MAPs), some of which may be related to tektins [49,50]. ... has grown longer through gene duplication. It is likely that many such questions will be answered as new. -
"Cytotoxicity of Aberrant Proteins". In: Encyclopedia of…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/50_Ashok_A_ELS_2008.pdf25 Sep 2008: Therefore, genetic mutations thatimpart a new or aberrant property on the protein to causecellular dysfunction are termed gain-of-function (GOF)diseases. -
Membrane Localization is Critical for Activation of the PICK1 BAR…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MadsenGetherTraffic2008.pdf18 Oct 2008: essential for induction of synaptic long-term depression. (LTD) (9,10) as well as for a new form of cerebellar synaptic. ... we present data providing new insight into the molecular. mechanisms controlling the activity of the PICK1 BAR. -
Thesis Chapter 0
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/Hardaker.pdf10 Jun 2008: suggested that goa-1 defined a new pathway, independent of the ones activated by flp-1 and. -
The GTPase-Activating Protein GRAF1 Regulates the CLIC/GEEC Endocytic …
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Lundmark_McMahon_GRAF2008.pdf28 Nov 2008: context of our findings, study of Cla-thrin-independent endocytic pathways will reveal new layersof complexity underlying lipid and protein cargo selection, ap-propriate intracellular trafficking of endocytic membranes, andthe mechanisms -
Mediation, Modulation, and Consequences of Membrane-Cytoskeleton…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DohertyMcMahonAnnRevBiophys08.pdf22 May 2008: These blebs are reversible, and re-versal requires actin polymerization into thesesites to provide new membrane-cytoskeletonlinkage. ... Upon recovery fromhypotonic stretch, cells shrink and new invagi-nations from the membrane are formed (133).The -
Molecular Biology of the CellVol. 19, 3463–3476, August 2008 ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/51_Ashok_A_MBC_2008.pdf16 Jul 2008: more generally, led to new insights into the deter-minants for QC of GPI-anchored proteins in the ER. ... All enzymes for cloning were ob-tained from New England Biolabs (Beverly, MA) with the exception of Pfupolymerase, which was from Stratagene (La -
The Hydrophobic Insertion Mechanism of Membrane Curvature Generation…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/CampeloBioPJ2008.pdf13 Dec 2008: The Hydrophobic Insertion Mechanism of Membrane CurvatureGeneration by Proteins. Felix Campelo,y Harvey T. McMahon,z and Michael M. KozlovDepartment of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, -
doi:10.1016/j.str.2008.06.010
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/18786397.pdf3 Sep 2008: to prepare grids for EM analysis. If no filaments were visible in this initial examination, the protein stock was incubated at 4C for 3–4 days and new EM. -
TH EJ OU RN AL OF CE LL BIO ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/53_Hegde_RS_JCB_2008.pdf22 Jul 2008: Although the study of essential and constitutive facets of translocation has required simple and highly robust model systems, the study of regulation will probably necessitate more complex substrates and potentially new
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