Search

21 Jul 2023: Scientific Facilities & Support Services One of the cornerstones of LMB science is the provision of excellent facilities and support services which

21 Jul 2023: Welfare and ethics Animal health and welfare is of paramount importance to staff at the LMB, from both an ethical view and to achieve robust and

11 Dec 2023: Electron Microscopy Electron Cryo-microscopy Course 2023 Electron Cryo-microscopy Course 2017 Below are recordings of the LMB's 2017 Cryo-microscopy

21 Jul 2023: Statistics Course 2014   Lectures Name Lecture Tutorial Tutorial Answers Use And Misuse of Statistics, And Introduction To R Descriptive Statistics

21 Jul 2023: LMB Research Involving Animals The pioneering work of the Nobel Prize winning LMB scientists, George Kohler and Cesar Milstein, involved the discovery of

21 Jul 2023: RNA-seq course 2020 An introduction to RNA-seq analysis using in-house software tools. RNA-Seq is a next-generation sequencing (NGS) technique designed to

21 Jul 2023: NMR NMR spectroscopy is a powerful method for resolving the structure, dynamics and interactions of proteins and nucleic acids in solution. Located in a

21 Jul 2023: Macromolecular Crystallisation Automated systems and protocols have been developed at the LMB for screening crystallisation conditions by vapor diffusion

21 Jul 2023: Why is animal research needed? Many medical advances have been facilitated or developed from research conducted using animals, benefitting both animal and

21 Jul 2023: Nanobody Mission The Nanobody facility provides a service for the selection and production of nanobodies from either phage display or yeast surface

8 Dec 2023: Scientific Computing Scientific Computing provides and supports the LMB’s core Unix systems. These systems include email, authenticating user access to

21 Jul 2023: Light Microscopy The modern form of the confocal microscope was developed at the LMB in the mid-80s, and instrument development continues today. Light

21 Jul 2023: Crystallography Course 2013 Lectures Lecture Presentations Tutorials Data Processing and Scaling - Phil Evans and Andrew Leslie Required Software

21 Jul 2023: Support services IT Support IT Support provides hardware and software configuration and an extensive and speedy repair service for Apple and Windows

21 Jul 2023: History of technology transfer The LMB’s translational strategies have evolved over time and with experience. Today, the approach taken in commercialising

21 Jul 2023: Examples of Recent Technology Transfer Initiatives Jason Chin – Establishment of Constructive Bio (2022) to develop technologies to assemble DNA on larger

21 Jul 2023: Flow Cytometry The LMB’s Flow Cytometry facility gives its researchers the ability to characterise, quantify and separate cell populations on the basis of

21 Jul 2023: Biological Services Group The LMB Biological Services Group (BSG) maintains state-of-the-art facilities to house breeding and experimental colonies of

21 Jul 2023: Mass Spectrometry Mass spectrometry based proteomic experiments have become an important tool for studying biological systems. We implement

21 Jul 2023: Concordat on Openness in Animal Research The Concordat on Openness is a declaration signed by many organisations involved with bioscience in the UK. The

21 Jul 2023: Image Processing Software MRC CAMBRIDGE IMAGE PROCESSING SYSTEM Richard Henderson, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge

21 Jul 2023: Therapeutic antibodies and the LMB The discovery of antibodies more than 100 years ago, prompted scientists to develop a number of animal and human

21 Jul 2023: Raphin 1 and phosphatase inhibitors technology (2018) Anne Bertolotti’s group in the LMB’s Neurobiology Division have developed the first platform to

21 Jul 2023: Neonatal Mouse Anaesthetisation Mould Request Form Researchers from Dr Ingo Greger’s laboratory at the MRC Laboratory of Molecular Biology have designed a

21 Jul 2023: Crystallisation and X-ray A high quality crystal will amplify the reflections of an intense, monochromatic, beam of light. The resulting diffraction

21 Jul 2023: Trim-AwayTM (2017) Trim-Away is a new technology, developed by Dean Clift, Melina Schuh and Leo James, for the rapid removal of specific proteins from

21 Jul 2023: Gold EM support grids (2015) Chris Russo is developing improved methods of specimen preparation for electron cryo-microscopy (cryo-EM). In 2014 Lori

21 Jul 2023: Mesolens microscopy (2009) The LMB’s Brad Amos is a key developer of confocal microscopy at the LMB and the creator of the Mesolens - a unique microscope

21 Jul 2023: Centre for Chemical and Synthetic Biology

21 Jul 2023: Bicycle Therapeutics Ltd (2009) Bicycle Therapeutics Ltd is a biotechnology company created in 2009 which has developed a novel technology platform for

21 Jul 2023: MORPHEUS III protein crystallization screen (2017) MORPHEUS III is a 96-condition 3D grid screen for protein crystallisation invented at the MRC

21 Jul 2023: Cell Penetrating Peptides and PepGen Limited (2018) Dr Mike Gait and his team together with Professor Matthew Wood’s laboratory at the University of

21 Jul 2023: Dr Goedert and his team generated and characterised a line of transgenic mice that constitutively express human tau with the P301S mutation (The Journal of Neuroscience, 2002, 22(21):9340).

21 Jul 2023: CombiPuckTM for X-ray crystallography (2017) Minmin Yu, Adam Fowle, Wai-Ching Hon and Andrew Leslie designed and built a prototype cryopuck (CombiPuckTM)

21 Jul 2023: Directed evolution of enzymes using in vitro compartmentalization (IVC) (2017) Philipp Holliger and his team at the MRC Laboratory of Molecular Biology

21 Jul 2023: SiR (Self-inactivating Rabies virus) - A new tool to study neural networks (2017) It is becoming progressively clearer that neural network dysfunction is