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Designer proteins to seek and destroy | Department of Pharmacology
https://www.phar.cam.ac.uk/news/BBSRC-funded-project15 May 2024: These will be adapted in two applications: First, the disruption of endogenous protein-protein interactions to control and direct cellular processes in which they are involved. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Ladds/pub15 May 2024: M. & Ladds. G. (2021) CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells. ... 2020) Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptors. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/lindon/pub15 May 2024: Cell density-dependent induction of endogenous myogenin (myf4) gene expression by Myf5. -
Group Summaries for Alumni | Department of Pharmacology
https://www.phar.cam.ac.uk/group-summaries-alumni15 May 2024: derived from the most clinically advanced AURKA inhibitor, alisertib, that are able to clear both endogenous and exogenous AURKA from cells and to downregulate its interphase functions. -
Dr Cathy Wilson | Department of Pharmacology
https://www.phar.cam.ac.uk/news/wilson15 May 2024: Her main area of research is to develop therapeutic strategies to either inhibit Myc driven transcription to develop new cancer therapies or enhance Myc driven transcription to stimulate endogenous tissue repair. -
Congratulations to Abigail Pearce for her successful PhD viva! |…
https://www.phar.cam.ac.uk/news/congratulations-abigail-pearce-her-successful-phd-viva15 May 2024: Viva. Her thesis she defended is entitled "Influence of Peptide Allosteric Modulators on Agonist Bias at Class B1 G protein-Coupled Receptors", which looks at the endogenous mechanisms by which Class -
Research Interest | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Ladds/research15 May 2024: We are also using new methods to aid in the de-orphanisation (identification of endogenous agonists) for olfactory receptors. -
Natural Sciences Tripos Part II Pharmacology or Biological and ...
https://www.phar.cam.ac.uk/system/files/documents/2020Coursebrochure.pdfsystems, whether the drug is synthetic, natural or endogenous. Pharmacologists. can use this information to reveal how the biological system itself works. -
Enterprise and Industry Collaboration | Department of Pharmacology
https://www.phar.cam.ac.uk/enterprise-and-industry-collaboration15 May 2024: mRNA cardiac regenerative therapeutic that drives endogenous healing. Contact us. Department of Pharmacology. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/taylor/Pub15 May 2024: Mol. Pharm. 92, 533-545. Keebler, MV & Taylor CW (2017) Endogenous signalling pathways and caged-IP3 evoke Ca2+ puffs at the same abundant immobile intracellular sites. ... 3. receptors requires an endogenous 1-8-14 calmodulin-binding motif. Biochem. J.
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