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Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: Circ Genom Precis Med. 2019;12:e002507. DOI: 10.1161/CIRCGEN.119.002507 September 2019 397. BACKGROUND: Pediatric cardiomyopathies are a clinically and genetically heterogeneous group of heart muscle disorders associated with high morbidity and -
doi:10.1016/j.cell.2006.01.047
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/16615893.pdf18 Apr 2006: levels, is that overexpression of exogenous Tsg101 se-. questers endogenous Tsg101 binding partners (Vps28. ... Tal, a Tsg101-spe-. cific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus. -
Membrane fusion is the process whereby two separate lipid ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MartensMcMahon2008.pdf16 May 2008: derived from a retrovirus. Syncytins function in cell–cell fusion during trophoblast formation. Immunoglobulin (Ig)-like Results that match 1 of 2 words
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Tumour prevention by a single antibody domaintargeting the…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17568777.pdf22 Jul 2007: cells infected with retrovirus only. Expression of intrabody. causes a morphological change in HT-1080 with reorganised. ... mice. All mice subcutaneously injected with EJ cells infected. with retrovirus only or retrovirus expressing the mutant. -
supplementary figures 070814 JL
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/scc32014si.pdf8 Aug 2014: microscopy (Fig 4A). (B) Cells with endogenous Scc1 or Scc3 (K20783) C-terminal. ... at the indicated time points and compared to levels made by endogenous tagged. -
7400749.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/41_Ashok_A_EMBORep_2006.pdf19 Jun 2006: J Cell Biol 129: 1509–1522. Morita E, Sundquist WI (2004) Retrovirus budding. ... Keywords: prions; retrovirus budding; exosome; endosomal transport;lysosome; multivesicular bodySubmitted 24 May 2006; accepted 31 May 2006. -
IntroductionThe endosomal system functions as an internal…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/SNX2Cullen2005.pdf17 Jan 2006: 5A,B). Furthermore,there was a clear enrichment of endogenous SNX2 on SNX1. ... Cells were then fixed and stained againstendogenous SNX1, endogenous SNX2 and endogenous mVps26. -
The Jour nal o f Cel l Bio logy ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/epsinR.pdf9 Jan 2003: Figure 6. Subcellular localization of epsinR. As a convention throughout the figure, myc-epsinR and mutants are labeled green and the endogenous proteins are labeled red. ... 3), and homologues are found in bothC. elegans and Drosophila. Thus, we used -
Acetylation of MEK2 and I{kappa}B kinase (IKK) activation loop…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/YopJ.pdf28 Nov 2006: 1d). Under our experimental conditions, endogenous levelsof MKK3 protein could not be detected by using the anti-MKK3antibody. ... This effect of expressed YopJ on endogenous MEK1/2was seen as early as 6 h after transfection of cells (data notshown). -
TBS may template.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/epsin/EM/mcmahon.pdf3 May 2002: This might be caused bycompetition for clathrin binding between the injectedpeptide and the endogenous protein, therebypreventing endogenous AP180 and AP2 frompromoting clathrin assembly at the plasmamembrane. -
Supplementary Figure 1Lysophosphatidic acid acyl transferase (LPAAT)…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/GallopEndoSupFigs.pdf4 Jan 2006: various endophilins and controls. a. b. c. Transformation of JC201 bacteria with endophilin does not lead to an acceleration of growth kinetics, unlike transformation of the endogenous LPAAT. -
A Ubiquitin Ligase-Associated Chaperone Holdase Maintains…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/72_Wang_Q_Mol_Cell_2011.pdf23 May 2012: IB, immunoblot-. ting. (B and C) Endogenous interactions between the. Bag6 and the gp78-p97 complexes. ... Trc35 Maintains a Cytosolic Pool of Bag6(A) Trc35 expression alters the subcellular localization of endogenous Bag6. -
doi:10.1016/j.devcel.2004.09.003
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15469844.pdf1 Nov 2004: InhVps37A and hVps37B (Bache et al., 2004; Stuchell et al.,addition, they play a critical role in retrovirus budding.2004), while the human ESCRT-II subunits correspondStructural understanding of ESCRT interaction ... The CCP4 suite: Morita, E., and -
The structural basis of novel endosome anchoringactivity of KIF16B ...
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17641687.pdf23 Jul 2007: performed dual immunofluorescence staining of expressed. KIF16B-PX and endogenous EEA1 using fixed HEK293 cells. ... In agreement with A431 cell localization, KIF16B-PX was. colocalized with endogenous EEA1 (Figure 6A). -
tra_578 1..18
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Burtey%20IVF%20Traffic%2007.pdf15 May 2007: colocalizing with endogenous AP-2 complexes (Figure 2. G–J). In contrast, the IVA mutation resulted in complete. ... plasma membrane (Figure 5A), which colocalized with both. clathrin–DsRed and endogenous AP-2 complexes (Figure 5. -
REPORT◥ PROTEOSTASIS UBE2O is a quality control factor fororphans ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017b.pdf4 Aug 2017: Catalytically inactive UBE2O(C1040S) alsorecovered endogenous and exogenous RPL24(but no detectable ubiquitinated forms), whereasUBE2O(DCR2) interacted poorly with RPL24 (fig.S10D). ... The heterogeneity of ubiquitin bands in the samples with cytosol is -
cm6307.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/TAXOL.C&B.pdf18 Feb 1999: Such molecules mightmimic an endogenous cellular factor, presumably a lesspotent one, that helps to stabilise microtubules in normalcytoplasm; the natural reagent might be a small molecule orpart of a microtubule-associated -
53091 361..366
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/McMahonE.pdf3 Dec 2004: endogenous AP2 (middle, AP6 antibody) and transferrin uptake (right). A strong. -
pnas201206839 17424..17429
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/23045692.pdf21 Nov 2012: Depletion of endogenous MITD1with two independent small interfering RNAs (siRNAs) resultedin phenotypes consistent with cytokinesis failure, as indicated bya six- to eightfold increase of multinucleated cells compared withcontrol siRNA-transfected -
doi:10.1016/j.cub.2004.09.077
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Snx1PeteCullen2004/Snx1PeteCullen2004.pdf23 Nov 2004: Endogenous SNX1 was enriched on tubularmembranes in close vicinity to endosomal vacuoles (Fig-ure 3). ... These data establish a role for endogenous SNX1in the retrieval of the CI-MPR from early endosomes tothe TGN.
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