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A fundamental protection mechanism against formalin in mammals is…
https://www2.mrc-lmb.cam.ac.uk/a-fundamental-protection-mechanism-against-formalin-in-mammals-is-revealed/25 Sep 2015: This was because endogenous formaldehyde destroyed the blood stem cells residing in the bone marrow. ... In these patients reducing or counteracting endogenous formaldehyde production may be of therapeutic value. -
Discovering the origins of biological timekeeping - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/discovering-the-origins-of-biological-timekeeping/20 Apr 2015: Published on. 20 April, 2015. The existence of an endogenous daily clock in humans is well known: it is what drives the 24-hour sleep/wake rhythm to match the daily -
doi:10.1016/j.cell.2007.01.036
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/46_Stefanovic_S_Cell_2007.pdf13 Apr 2015: Totest this, we analyzed the interactions between Sec61band endogenous TRC40 versus exogenously added (andepitope-tagged) TRC40-DN. ... with release from endogenous TRC40. 1156 Cell 128, 1147–1159, March 23, 2007 ª2007 Elsevier Inc. -
elife.elifesciences.org MacKinnon et al. eLife 2014;3:e01483. DOI:…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/83_MacKinnon_AL_eLife_2014.pdf9 Sep 2015: Upon induction with tetracycline, both wild-type and mutant Sec61 transgenes (untagged) were expressed at similar levels as the endogenous protein (Figure 6—figure supplement 1C). ... Because we could not easily distinguish endogenous Sec61 from the -
2168 | K. von der Malsburg et al. Molecular ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/93_vonderMalsburg-_K_MBC_2015.pdf11 Aug 2015: Because stable association of NEMF with 60S requires a peptidyl-tRNA (Shao et al., 2015), these complexes are likely to contain endogenous nascent chains. ... We examined this idea by analysis of endogenous RNCs on ER microsomes isolated from native -
ELIFE07975 1..21
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/94_Voorhees_RM_eLife_2015.pdf11 Aug 2015: By contrast, endogenous SRP in a homologous mammalian system hasa remarkably subtle effect on translation elongation (Wolin and Walter, 1989). ... Here we demonstrate that endogenous SRP is efficiently recruited to mammalian ribosomescontaining a -
KWRM_A_992668_O
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-3.pdf20 Oct 2015: elegans neurons using cell-specificpromoters. Since connexins should not. interact with endogenous innexins fromother neighboring neurons, we expected anew gap junction to form exclusivelybetween connexin-expressing neurons Aand B (Fig. ... elegans -
Sensory Neurons Arouse C. elegans Locomotion via Both Glutamate and…
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-4.pdf30 Jun 2015: Under these conditions, we only observed endogenous acetylcholine EPSCs. To recordGABAergic postsynaptic currents, the holding potential was 0 mV, at which we only observemIPSCs. ... Supporting InformationS1 Fig. Stimulus-evoked EPSCs and endogenous
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