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  2. The Jour nal o f Cel l Bio logy ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/24_Fons_RD_JCB_2003.pdf
    6 Feb 2003: The. Jour. nal o. f Cel. l Bio. logy. JCB. Article. The Journal of Cell Biology, Volume 160, Number 4, February 17, 2003 529–539http://www.jcb.org/cgi/doi/10.1083/jcb.200210095 529. Substrate-specific function of the translocon-associated protein
  3. Supplemental Materials Supp MethodsSupp Fig. 1 Sequence conservation…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004Sup.pdf
    23 Nov 2004: In the supplementary material of the previous paper we showed that these puncta co-localisedwith endogenous endocytic components such as eps15 and dynamin.
  4. PII: S1534-5807(04)00100-5

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Johannes_DevCell2004.pdf
    22 Mar 2005: Bar 10 m. endogenous MPR300 and TGN46 were relocalized to these conditions was not addressed directly. ... In agreement with these observations, we foundthat the endogenous EGF receptor was not relocalizedmembranes.
  5. 15955888524538 1..29

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2020/09/eLife_2020b.pdf
    24 Jul 2020: Juszkiewicz et al., 2018; Mills et al., 2016). Here, collisions were incurred on endogenous haemo-.
  6. SVUS002-16.tex

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/31_Rane_Chapter_2005.pdf
    21 Sep 2006: As predicted, these mice are resis-tant to prion infection and propogation41,42, consistent with a require-ment for endogenous PrPC in the replication of PrPSc.
  7. Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/PDF/Publications/acs.biochem.9b00296.pdf
    31 Jul 2019: 2011) Endogenous Myc maintains the tumormicroenvironment. Genes Dev. 25, 907916.(14) Gabay, M., Li, Y., and Felsher, D.
  8. Cellular/Molecular Endophilin Drives the Fast Mode of Vesicle…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Llobet%20J%20Neurosci2011.pdf
    23 Sep 2011: 5C), indicating that the competitive interactionwith endogenous endophilin occurred at the membrane.
  9. JOURNAL OF VIROLOGY, Feb. 2004, p. 2088–2099 Vol. 78, ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/27_Tremblay_P_JV_2004.pdf
    15 Jan 2004: Prnp0/0, except for Tg(MoPrP)4053/Prnp/, in which the endogenous Prnp genewas maintained by breeding with FVB mice (Charles River Laboratories, Hol-lister, Calif.).
  10. Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/COVID%20vaccine%202021%201873-3468.14171.pdf
    29 Aug 2021: Iba1) or 60 min at 37 C (anti-CD3, anti-CD4). This wasfollowed by blocking of endogenous peroxidase (peroxidase.
  11. LETTERS Architectural and mechanistic insights into an EHDATPase…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DaumkeMcMahonEHDNature/Daumke_McMahon_EHD.pdf
    28 Sep 2007: 1e, endogenous EHD2 in various cell lines shows asimilar peripheral distribution5,14).
  12. 16001658465475 1..36

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Collier_2020_elife-59560-v1.pdf
    15 Sep 2020: Cells were arrested in G1 with a-factor prior. to release into auxin and nocodazole containing media at 25˚C to deplete the endogenous Scc3.
  13. Diverse cytomotive actins and tubulins share a polymerization switch…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Wagstaff%202023Sci%20Advances%20cytomotive%20switch%20sciadv.adf3021.pdf
    16 Jul 2023: Note that using this pro-cedure, only the α-tubulin is overexpressed, and this is enough torecover functional αβ-tubulin heterodimers, as the recombinantα-tubulin associates with endogenous β-tubulin. ... The absence of endogenous, untagged
  14. A ribosome-associating factor chaperones tail-anchored membrane…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/66_Mariappan_M_Nature_2010.pdf
    1 Aug 2010: LETTERS. A ribosome-associating factor chaperonestail-anchored membrane proteinsMalaiyalam Mariappan1, Xingzhe Li1,2, Sandra Stefanovic1, Ajay Sharma1, Agnieszka Mateja3, Robert J. Keenan3. & Ramanujan S. Hegde1. Hundreds of proteins are inserted
  15. JCB Article The Journal of Cell Biology, Volume 164, ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/28_Snapp_EL_JCB_2004.pdf
    15 Apr 2004: These conclu-sions suggested that, in principle, the organization of multi-protein complexes could be assessed with antibody probes.Thus, if endogenous translocon components could be labeledwith dye-conjugated antibodies while
  16. Molecular mechanism and physiological functions of clathrin-mediated…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/McMahon%20NRMB%202011.pdf
    19 Jul 2011: Nature Reviews Molecular Cell Biology 12, 517 (2011). doi:10.1038/nrm3151
  17. Articleshttps://doi.org/10.1038/s41594-019-0196-z A folded…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Burmann%20NSMB%202019%20SI.pdf
    26 Feb 2019: c, Growth of strains containing point mutations at the elbow in the endogenous mukB gene.
  18. An intramembrane chaperone complex facilitates membrane protein…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2020/09/Nature_2020.pdf
    17 Aug 2020: Endogenous haemoglobin (around 60 kDa) from the translation extract was visualized by Coomassie staining of the same gel.
  19. doi:10.1016/j.cell.2006.10.032

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/43_Kang_SW_Cell_2006.pdf
    30 Nov 2006: Substrate-Specific TranslocationalAttenuation during ER Stress Definesa Pre-Emptive Quality Control PathwaySang-Wook Kang,1,4 Neena S. Rane,1,4 Soo Jung Kim,2 Jennifer L. Garrison,3 Jack Taunton,3. and Ramanujan S. Hegde1,1 Cell Biology and
  20. Mechanisms of Dense Core Vesicle Recapture following “Kiss andRun” ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Insulin_Tsuboi_JBC2004/Insulin_TsuboiJBC2004.pdf
    6 Dec 2004: K535A), or amphiphysin-1, all likely tobind to key interacting partners of endogenous dynamin, mightchange the diameter of the fusion pore and thus change thekinetics of tPA or NPY release.
  21. The Biogenesis of Multipass Membrane Proteins

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/CSHL_Persp_2022.pdf
    13 Sep 2022: The Biogenesis of Multipass Membrane Proteins. Luka Smalinskait _e and Ramanujan S. Hegde. MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom. Correspondence: rhegde@mrc-lmb.cam.ac.uk. Multipass membrane proteins contain two or
  22. Bb9e55.qxd

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Vallis_McMahon1999.pdf
    21 Mar 2003: Mol Biol Cell 1998, 9:195a. 22. Tuma PL, Stachniak MC, Collins CA: Activation of dynamin GTPaseby acidic phospholipids and endogenous rat brain vesicles. ... such adynaminPH construct into COS cells will be even betterat sequestering endogenous dynamin
  23. The mechanisms of integral membrane protein biogenesis

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/NRMCB_2021.pdf
    22 Sep 2021: Nature Reviews Molecular Cell Biology, doi:10.1038/s41580-021-00413-2
  24. 15919734904046 1..30

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2020/09/eLife_2020.pdf
    12 Jun 2020: phases from a single-wavelength anomalous diffraction (SAD) experiment using endogenous sulphur.
  25. 1256917combinedsupplement

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Gligoris-SM.pdf
    14 Nov 2014: Scc1’s endogenous M1 has been deleted, an N-terminal myc9 epitope was fused in frame and endogenous M30 was changed to I30. ... Endogenous Scc1M102, Smc3M139 and M186 generate a 30 kDa Scc1 and a 5 kDa Smc3 fragment.
  26. 554 Research Paper Inhibition of receptor-mediated endocytosis by the …

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/wigge_McMahon1997.pdf?cmd=Retrieve&db=PubMed&list_uids=9348539&dopt=Abstract
    21 Mar 2003: The most likely explanation for this is that theinteraction of dynamin with endogenous amphiphysin wasdisrupted in these cells. ... J Cell Biol 1993, 127:725-735. 18. Tuma PL, Stachniak MC, Collins CA: Activation of dynamin GTPaseby acidic phospholipids
  27. A positively charged channel within the Smc1/Smc3 hinge required for…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embosmcjingekurze2010.pdf
    1 Dec 2010: together with endogenous Smc3. Western blotting revealed. that immunoprecipitates of Smc3-HA3 or Smc3AAA-HA3. ... As expected, similar amounts of Smc1-myc9 and endogenous. Smc1 associate with Smc3-HA3.
  28. The ER membrane protein complex is a transmembrane domain insertase

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017c.pdf
    27 Jan 2018: This system contains endogenous mRNAs (primarily encoding the 14 kD globins and a prominent 70 kD protein) that contribute to background, but has the advantage of retaining native cytosolic conditions, most ... aureus is used to digest endogenous mRNA.
  29. © 2005 Nature Publishing Group Endophilin and CtBP/BARS are ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/GallopEndopohilinNature2005.pdf
    4 Jan 2006: A JC201 strain ofEscherichia coli lacking endogenous LPAAT activity grows at 30 8Cbut not at 42 8C (ref. ... coli that has no endogenous LPAATactivity (JC201 strain) cannot growat 42 8C (sector 1).
  30. doi:10.1016/j.devcel.2008.06.015

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/54_Rane_NS_DevCell_2008.pdf
    18 Sep 2008: Ifn-PrP. Note the lack of changes to endogenous PrP in cells expressing. ... Thus, in both cases, Ifn-PrP is not being overexpressed relative. to endogenous PrP.
  31. Membrane curvature sensing and induction: The function of BAR domains …

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/BARdomains/BARsupp.pdf
    20 Nov 2003: S6. Colocalization of wild type, mutant, and endogenous arfaptin with TGN46 Table S1.
  32. pq240013132p

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/16_Wilhelm_JE_PNAS_2000.pdf
    10 Nov 2000: 1B), despitethe fact that endogenous Vg1 was expressed only in the late-stageoocytes (Fig. ... 1C). This result raisesthe possibility that the endogenous, localized Vg1 message is inan environment that is free from repression.
  33. TBS may template.qxd

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/EMreview.pdf
    3 May 2002: This might be caused bycompetition for clathrin binding between the injectedpeptide and the endogenous protein, therebypreventing endogenous AP180 and AP2 frompromoting clathrin assembly at the plasmamembrane.
  34. Cooperative Recruitment of Dynamin and BIN/Amphiphysin/Rvs (BAR)…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/JBC_Meinecke2013.pdf
    19 Mar 2013: Amph12 RNAi) depletion on the recruitment of endogenous dynamin 2 (dynaminen, green and white arrows) and clathrin light chain A (clathrinen, red). ... Bar, 10µm (B) Effect of SNX9, amphiphysin and endophilin overexpression on endogenous dynamin 2
  35. Transmembrane Domain Modulates Sorting of MembraneProteins in…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/29_Karsten_V_JBC_2004.pdf
    2 Jun 2004: 1B).BAPGRA4 was localized to dense granules as evidenced bycolocalization with the endogenous dense granule proteinGRA3 (32). ... Both endogenous GRA4 andBAPGRA4 were efficiently translocated across the ER mem-brane (Fig.

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