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Covid19 Image - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fdownload%2Fcovid19-image-download%2F&format=xmlcam.ac.uk/download/covid19-image-download/">Covid19 Image</a></blockquote><iframe sandbox="allow-scripts" security="restricted" -
pnas201205508 15259..15264
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/22949682.pdf25 Nov 2012: Oncogenic mutations mimic and enhance dynamicevents in the natural activation of phosphoinositide3-kinase p110α (PIK3CA)John E. Burke, Olga Perisic, Glenn R. Masson, Oscar Vadas, and Roger L. Williams1. Laboratory of Molecular Biology, Medical -
Crystal Structure of the Two N-terminal Domains of g3p from…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10329170.pdf6 May 1999: Article No. jmbi.1999.2720 available online at http://www.idealibrary.com on J. Mol. Biol. (1999) 288, 649657. Crystal Structure of the Two N-terminal Domains ofg3p from Filamentous Phage fd at 1.9 AÊ : Evidence forConformational Lability. Philipp -
pnas201206839 17424..17429
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/23045692.pdf21 Nov 2012: ESCRT-III binding protein MITD1 is involved incytokinesis and has an unanticipated PLD foldthat binds membranesMichael A. Haddersa,1, Monica Agromayorb,2,1, Takayuki Obitaa,3, Olga Perisica, Anna Caballeb, Magdalena Klocb,Meindert H. Lamersa, Roger -
doi:10.1016/j.coph.2005.03.002
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15963759.pdf12 Nov 2006: Phosphoinositide 3-kinases as drug targets in cancerLen Stephens1, Roger Williams2 and Phillip Hawkins1. The past two years have seen phosphoinositide 3-kinases. (PI3Ks) move from being seen as potential targets for. chemotherapeutics, to one of -
PII: S1388-1981(99)00150-X
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10570253.pdf20 Apr 2002: Review. Mammalian phosphoinositide-speci¢c phospholipase C. Roger L. Williams Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. Received 1 April 1999 ; received in revised form 17 June 1999 ; accepted 31 -
A Ternary Metal Binding Site in the C2 Domain ...
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9062102.pdf20 Apr 2002: A Ternary Metal Binding Site in the C2 Domain of Phosphoinositide-SpecificPhospholipase C-δ1†,‡. Lars-Oliver Essen,,| Olga Perisic, Denise E. Lynch, Matilda Katan, and Roger L. Williams,. Centre for Protein Engineering, MRC Centre, Hills Road, -
file:///Users/flong/workplace/balbes_web/MRC-LMB/Webpage/content/balbe…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/balbes/documentation_fs/manual_115.pdf9 Feb 2012: LinuxII. Mac OS X. The latest versions can be download at MRC-LMB site or YSBL site. ... 1. Download a version of BALBES database, e.g. BALBES__DB.tar.gz.2. Move the database you have downloaded to the directory where your environment variable. -
tutorial-2.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/tutorial-2.pdf16 May 2010: Do you prefer that? Why? Use the EDS service to download 1H4P. -
Structural Insights into Endosomal Sorting Complex Required…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15044434.pdf24 Sep 2004: Structural Insights into Endosomal Sorting Complex Required forTransport (ESCRT-I) Recognition of Ubiquitinated Proteins. Received for publication, January 5, 2004, and in revised form, March 22, 2004Published, JBC Papers in Press, March 24, 2004, -
Catalytic Domain of Phosphoinositide-specificPhospholipase C…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9565585.pdf20 Apr 2002: Catalytic Domain of Phosphoinositide-specificPhospholipase C (PLC)MUTATIONAL ANALYSIS OF RESIDUES WITHIN THE ACTIVE SITE AND HYDROPHOBIC RIDGE OF PLCd1. (Received for publication, November 20, 1997, and in revised form, February 18, 1998). Moira V. -
N402_18f 313..320
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10580505.pdf11 Nov 1999: 1999 Macmillan Magazines Ltd. letters to nature. NATURE | VOL 402 | 18 NOVEMBER 1999 | www.nature.com 313. 12. Macleod, K. F. et al. p53-dependent and independent expression of p21 during cell growth,. differentiation, and DNA damage. Genes Dev. 9, -
bc219914979p
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10329700.pdf20 Apr 2002: Mapping the Phospholipid-binding Surface and TranslocationDeterminants of the C2 Domain from Cytosolic Phospholipase A2. (Received for publication, November 9, 1998, and in revised form, January 14, 1999). Olga Perisic‡, Hugh F. Paterson, Georgina -
Phosphoinositide-Specific Phospholipase Cδ1 Activity toward Micellar…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9287165.pdf20 Apr 2002: Phosphoinositide-Specific Phospholipase Cδ1 Activity toward Micellar Substrates,Inositol 1,2-Cyclic Phosphate, and Other Water-Soluble Substrates: A Sequential. Mechanism and Allosteric Activation†. Yiqin Wu,‡ Olga Perisic, Roger L. Williams, -
Tumour prevention by a single antibody domaintargeting the…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17568777.pdf22 Jul 2007: Tumour prevention by a single antibody domaintargeting the interaction of signal transductionproteins with RAS. Tomoyuki Tanaka, Roger L Williamsand Terence H Rabbitts. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK. Many -
PII: S1097-2765(01)00372-0
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/11684018.pdf20 Apr 2002: Molecular Cell, Vol. 8, 829–839, October, 2001, Copyright 2001 by Cell Press. The Crystal Structure of the PX Domain from p40phoxBound to Phosphatidylinositol 3-Phosphate. Vam7 (Cheever et al., 2001), SNX3 (Xu et al., 2001b),and p40 phox -
The Structure of a Tunicate C-type Lectin from Polyandrocarpa…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10398588.pdf7 Jul 1999: Article No. jmbi.1999.2910 available online at http://www.idealibrary.com on J. Mol. Biol. (1999) 290, 867879. The Structure of a Tunicate C-type Lectin fromPolyandrocarpa misakiensis Complexed withD-Galactose. Se bastien F. Poget1, Glen B. Legge1, -
Structural and Mechanistic Comparison of Prokaryotic and Eukaryotic…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9466937.pdf15 Jan 1998: Structural and Mechanistic Comparison of Prokaryoticand Eukaryotic Phosphoinositide-specificPhospholipases C. Dirk W. Heinz1, Lars-Oliver Essen2 and Roger L. Williams3. 1Institut fuÈ r OrganischeChemie und BiochemieUniversitaÈt -
Structural Mapping of the Catalytic Mechanism for a…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9048554.pdf20 Apr 2002: Structural Mapping of the Catalytic Mechanism for a MammalianPhosphoinositide-Specific Phospholipase C†,‡. Lars-Oliver Essen,,| Olga Perisic, Matilda Katan, Yiqin Wu, Mary F. Roberts, and Roger L. Williams,. Centre for Protein Engineering, MRC -
Autism
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/ImaginingTheBrain/2012/media/ASC.pptx21 Feb 2012: Autism. What is Autism? Autism is a spectrum of neurodevelopmental conditions, characterised by a Triad of Impaiments. Autism is a spectrum condition. This means that the symptoms experienced can vary from very mild, which may never be diagnosed, to -
Regulation of lipid binding underlies the activation mechanism of…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/22120714.pdf21 Nov 2012: Oncogene 31, 3655 (2012). doi:10.1038/onc.2011.532 -
doi:10.1016/j.devcel.2004.09.003
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15469844.pdf1 Nov 2004: Developmental Cell, Vol. 7, 559–569, October, 2004, Copyright 2004 by Cell Press. ESCRT-II, an Endosome-Associated Complex Requiredfor Protein Sorting: Crystal Structure andInteractions with ESCRT-III and Membranes. Ten of these proteins are -
©20 10 N atur e A mer ica, Inc. ...
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20081827.pdf2 Aug 2010: 20. 10 N. atur. e A. mer. ica,. Inc. All. righ. ts r. eser. ved. NATURE CHEMICAL BIOLOGY | VOL 6 | FEBRUARY 2010 | www.nature.com/naturechemicalbiology 1 1 7. ARTICLEPUBLISHED ONLINE: 10 JANUARY 2010 | DOI: 10.1038/NCHEMBIO.293. The PI(3)Ks are -
x96255u149
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/11090628.pdf20 Apr 2002: Molecular Cell, Vol. 6, 909–919, October, 2000, Copyright 2000 by Cell Press. Structural Determinants of Phosphoinositide3-Kinase Inhibition by Wortmannin, LY294002,Quercetin, Myricetin, and Staurosporine. for proteins such as protein kinase B -
LMB-Timeline-poster 2020 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fdownload%2Flmb-timeline-poster-2019%2F&format=xmlcam.ac.uk/download/lmb-timeline-poster-2019/">LMB-Timeline-poster 2020</a></blockquote><iframe sandbox="allow-scripts" security="restricted" -
Briggs SARS-CoV-2 Image - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fdownload%2Fbriggs-nature-cover%2F&format=xmlcam.ac.uk/download/briggs-nature-cover/">Briggs SARS-CoV-2 Image</a></blockquote><iframe sandbox="allow-scripts" security="restricted" -
25 Structural studies of phosphoinositide 3-kinase-dependent traffi c …
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17233579_proof.pdf14 Jun 2007: 25. Structural studies of phosphoinositide 3-kinase-dependent traffi c to multivesicular bodiesDavid J. Gill1, Hsiangling Teo1, Ji Sun‡, Olga Perisic, Dmitry B. Veprintsev†, Yvonne Vallis, Scott D. Emr‡ and Roger L. Williams2. MRC Laboratory -
tutorial-2.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/tutorial-2.pdf16 May 2010: Do you prefer that? Why? Use the EDS service to download 1H4P. -
Paul EmsleyMRC Laboratory of Molecular Biology, Cambridge, UKJune…
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/Ligands-July-2015-v2.pdf16 Jul 2015: One by one download the wwPDB definition mmcif. – Total: 15168. – ... Download all these minimal descriptions and run Acedrg. – 7360 cif files generated (93% coverage). -
Getting on your Nerves
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/ImaginingTheBrain/2012/media/GettingOnYourNerves.pptx22 Feb 2012: Getting on your Nerves. What a lot of nerve! There are about 100,000,000,000 neurons in an adult human. These form 10,000,000,000,000 synapses, or connections. They represent 2% of the body’s weight, 0.04-0.07% cells and 20-44% of the body’s -
A ribosome-associating factor chaperones tail-anchored membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/66_Mariappan_M_Nature_2010.pdf1 Aug 2010: LETTERS. A ribosome-associating factor chaperonestail-anchored membrane proteinsMalaiyalam Mariappan1, Xingzhe Li1,2, Sandra Stefanovic1, Ajay Sharma1, Agnieszka Mateja3, Robert J. Keenan3. & Ramanujan S. Hegde1. Hundreds of proteins are inserted -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/11583
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/11583{"id":11583,"date":"2018-03-01T08:59:16","date_gmt":"2018-03-01T08:59:16","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=11583"},"modified":"2023-07-21T12:49:53","modified_gmt":"2023-07-21T11:49:53","slug":"biophysics-lectures","status": -
PowerPoint Presentation
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Interactomes/NetworkWebTalk_files/NetworkWebTalk.html.ppt21 Aug 2007: Dynamic networks. &. clathrin-mediated. endocytosis. Gerrit Praefcke. (now at Cologne). Marijn Ford. (now at UC Davis). Eva Schmid. (LMB Cambridge). The Interactome web pages were written to accompany Schmid and McMahon (Nature 2007) and this talk -
Doc2b Is a High-Affinity Ca2+ Sensor forSpontaneous Neurotransmitter…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/GroffenScience2010.pdf30 Apr 2010: Doc2b Is a High-Affinity Ca2+ Sensor forSpontaneous Neurotransmitter ReleaseAlexander J. Groffen,1 Sascha Martens,2† Rocío Díez Arazola,1 L. Niels Cornelisse,1Natalia Lozovaya,1,3,4 Arthur P. H. de Jong,1 Natalia A. Goriounova,1,3 Ron L. P. -
Coot Updates Paul EmsleySept 2016 Coot 0.8.4 Released● Patterson ...
https://www2.mrc-lmb.cam.ac.uk/coot/ligands/2016/emsley-ccp4-ligand-meeting-sept-2016-v5.pdf28 Sep 2016: Search” comp_id (2GM) Download $ pyrogen -Mn --comp_id AAA -R 2GM.cif problem-2.smi. -
80096 RPF
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/EMBO2012FtsAPiotr/emboj201276s3.pdf7 Mar 2012: The EMBO Journal Peer Review Process File - EMBO-2011-80096. European Molecular Biology Organization 1. Manuscript EMBO-2011-80096 FtsA forms actin-like protofilaments Piotr Szwedziak, Qing Wang, Stefan MV Freund and Jan Löwe Corresponding author: -
Coot Tools for Cryo-EM Paul EmsleyMRC Laboratory of Molecular ...
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-Aug-Stockholm.pdf15 Aug 2018: Download Binaries pre-release experimental. Model-Building Tools. Recent Developments. 8/90. Model-Building Tools. -
PowerPoint Presentation
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/ImaginingTheBrain/2014/media/Changing_Brains_Neurotechnology_website.pptx2 May 2013: Changing Brains. Neurotechnology The Artificial Brain? Medical Electronics. Nervous System. Neurotechnology is any technology that improves or repairs nervous system function or facilitates understanding of the nervous system. Brain-machine -
LMB COVID-19 response - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/lmb-covid-19-response/22 Nov 2023: RBD = Receptor Binding Domain. Image available to download and use under a CC-BY-NC-ND 4.0 International license. ... Image available to download and use under a CC-BY-NC-ND 4.0 International license.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14{"id":14,"date":"2012-06-25T09:56:10","date_gmt":"2012-06-25T09:56:10","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=14"},"modified":"2023-07-21T12:49:24","modified_gmt":"2023-07-21T11:49:24","slug":"history-of-the-lmb","status -
Meet the LMBees - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/meet-the-lmbees/3 Jul 2018: The LMB has recently become home to 16,000 honey bees, representing two nucs (also known as nucleus colonies) which will form the basis of two new hives.
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https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-json/wp/v2/pages/20
https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-json/wp/v2/pages/20 -
Biophysics Lectures - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-training/biophysics-lectures/21 Jul 2023: Technique. Speaker. Download Talks. Introduction to Light Microscopy. Nick Barry.
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Resources - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/resources/21 Jul 2023: Resources Take a look at our variety of resources. Whether you are looking for an activity to do at home, are a local primary school teacher hoping to
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Locally Developed Software - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/locally-developed-software/7 Jun 2024: Can either use user-supplied homologous structures, or run an automated BLAST search and download homologues from the PDB.
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AP2 adaptors for clathrin-mediated endocytosis: These are Cargo…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Adaptors/index.html26 Sep 2011: Classical adaptors: e.g. the AP2 adaptor complex. appendages). The hinge domains bind to clathrin terminal domains. AP1, AP3 and AP4 adaptors have similar subunit compositions and bind to different cargo and accessory proteins (see Adaptor table 1). -
How To Apply - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/students/international-phd-programme/how-to-apply/6 Sep 2023: You can download the LMB PhD Statement of Interest Form here. ... If you would like more information on how your application will be processed a chart with an outline of the application process is available to download here under ‘What is the
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> Home > Software > BALBES > Download
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/balbes/download_fs/dow_nav.html31 Jan 2012: -
Contents:
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/balbes/documentation_fs/manual_115.html31 Jan 2012: Mac OS X. The latest versions can be download at MRC-LMB site or YSBL site. ... You need to do the following steps. After you download one of gziped tar files, e.g. -
Worms are cleverer than you think! – Just another LMB Group Multi…
https://www2.mrc-lmb.cam.ac.uk/groups/worms/Just another LMB Group Multi Sites site
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