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25 Nov 2012: Oncogenic mutations mimic and enhance dynamicevents in the natural activation of phosphoinositide3-kinase p110α (PIK3CA)John E. Burke, Olga Perisic, Glenn R. Masson, Oscar Vadas, and Roger L. Williams1. Laboratory of Molecular Biology, Medical

6 May 1999: Article No. jmbi.1999.2720 available online at http://www.idealibrary.com on J. Mol. Biol. (1999) 288, 649657. Crystal Structure of the Two N-terminal Domains ofg3p from Filamentous Phage fd at 1.9 AÊ : Evidence forConformational Lability. Philipp

21 Nov 2012: ESCRT-III binding protein MITD1 is involved incytokinesis and has an unanticipated PLD foldthat binds membranesMichael A. Haddersa,1, Monica Agromayorb,2,1, Takayuki Obitaa,3, Olga Perisica, Anna Caballeb, Magdalena Klocb,Meindert H. Lamersa, Roger

12 Nov 2006: Phosphoinositide 3-kinases as drug targets in cancerLen Stephens1, Roger Williams2 and Phillip Hawkins1. The past two years have seen phosphoinositide 3-kinases. (PI3Ks) move from being seen as potential targets for. chemotherapeutics, to one of

20 Apr 2002: Review. Mammalian phosphoinositide-speci¢c phospholipase C. Roger L. Williams Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. Received 1 April 1999 ; received in revised form 17 June 1999 ; accepted 31

20 Apr 2002: A Ternary Metal Binding Site in the C2 Domain of Phosphoinositide-SpecificPhospholipase C-δ1†,‡. Lars-Oliver Essen,,| Olga Perisic, Denise E. Lynch, Matilda Katan, and Roger L. Williams,. Centre for Protein Engineering, MRC Centre, Hills Road,

9 Feb 2012: LinuxII. Mac OS X. The latest versions can be download at MRC-LMB site or YSBL site. ... 1. Download a version of BALBES database, e.g. BALBES__DB.tar.gz.2. Move the database you have downloaded to the directory where your environment variable.

16 May 2010: Do you prefer that? Why? Use the EDS service to download 1H4P.

24 Sep 2004: Structural Insights into Endosomal Sorting Complex Required forTransport (ESCRT-I) Recognition of Ubiquitinated Proteins. Received for publication, January 5, 2004, and in revised form, March 22, 2004Published, JBC Papers in Press, March 24, 2004,

20 Apr 2002: Catalytic Domain of Phosphoinositide-specificPhospholipase C (PLC)MUTATIONAL ANALYSIS OF RESIDUES WITHIN THE ACTIVE SITE AND HYDROPHOBIC RIDGE OF PLCd1. (Received for publication, November 20, 1997, and in revised form, February 18, 1998). Moira V.

11 Nov 1999: 1999 Macmillan Magazines Ltd. letters to nature. NATURE | VOL 402 | 18 NOVEMBER 1999 | www.nature.com 313. 12. Macleod, K. F. et al. p53-dependent and independent expression of p21 during cell growth,. differentiation, and DNA damage. Genes Dev. 9,

20 Apr 2002: Mapping the Phospholipid-binding Surface and TranslocationDeterminants of the C2 Domain from Cytosolic Phospholipase A2. (Received for publication, November 9, 1998, and in revised form, January 14, 1999). Olga Perisic‡, Hugh F. Paterson, Georgina

20 Apr 2002: Phosphoinositide-Specific Phospholipase Cδ1 Activity toward Micellar Substrates,Inositol 1,2-Cyclic Phosphate, and Other Water-Soluble Substrates: A Sequential. Mechanism and Allosteric Activation†. Yiqin Wu,‡ Olga Perisic, Roger L. Williams,

22 Jul 2007: Tumour prevention by a single antibody domaintargeting the interaction of signal transductionproteins with RAS. Tomoyuki Tanaka, Roger L Williamsand Terence H Rabbitts. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK. Many

20 Apr 2002: Molecular Cell, Vol. 8, 829–839, October, 2001, Copyright 2001 by Cell Press. The Crystal Structure of the PX Domain from p40phoxBound to Phosphatidylinositol 3-Phosphate. Vam7 (Cheever et al., 2001), SNX3 (Xu et al., 2001b),and p40 phox

7 Jul 1999: Article No. jmbi.1999.2910 available online at http://www.idealibrary.com on J. Mol. Biol. (1999) 290, 867879. The Structure of a Tunicate C-type Lectin fromPolyandrocarpa misakiensis Complexed withD-Galactose. Se bastien F. Poget1, Glen B. Legge1,

15 Jan 1998: Structural and Mechanistic Comparison of Prokaryoticand Eukaryotic Phosphoinositide-specificPhospholipases C. Dirk W. Heinz1, Lars-Oliver Essen2 and Roger L. Williams3. 1Institut fuÈ r OrganischeChemie und BiochemieUniversitaÈt

20 Apr 2002: Structural Mapping of the Catalytic Mechanism for a MammalianPhosphoinositide-Specific Phospholipase C†,‡. Lars-Oliver Essen,,| Olga Perisic, Matilda Katan, Yiqin Wu, Mary F. Roberts, and Roger L. Williams,. Centre for Protein Engineering, MRC

21 Feb 2012: Autism. What is Autism? Autism is a spectrum of neurodevelopmental conditions, characterised by a Triad of Impaiments. Autism is a spectrum condition. This means that the symptoms experienced can vary from very mild, which may never be diagnosed, to