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  2. Phosphoinositide-specific Phospholipase C: Structural Basis for…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10024492.pdf
    11 Jun 1997: Phosphoinositide-specific phospholipase C: structural basisfor catalysis and regulatory interactionsMatilda Katan and Roger L. Williams. Phosphoinositide-specific phospholipase C (PI-PLC) isozymeshave an important role in cellular responses to a
  3. Crystal Structure of a Calcium-Phospholipid Binding Domainfrom…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9430701.pdf
    20 Apr 2002: Crystal Structure of a Calcium-Phospholipid Binding Domainfrom Cytosolic Phospholipase A2. (Received for publication, September 24, 1997). Olga Perisic‡, Sun Fong, Denise E. Lynch‡, Mark Bycroft, and Roger L. Williams‡. From the ‡Medical
  4. validation-tutorial.dvi

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/validation-tutorial.pdf
    24 Oct 2017: How might you fix it? 7 Freestyle. Use the EDS to download the structure and data/map for 1BAV.
  5. Crystal Structure of the Two N-terminal Domains of g3p from…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10329170.pdf
    6 May 1999: Article No. jmbi.1999.2720 available online at http://www.idealibrary.com on J. Mol. Biol. (1999) 288, 649657. Crystal Structure of the Two N-terminal Domains ofg3p from Filamentous Phage fd at 1.9 AÊ : Evidence forConformational Lability. Philipp
  6. pnas201205508 15259..15264

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/22949682.pdf
    25 Nov 2012: Oncogenic mutations mimic and enhance dynamicevents in the natural activation of phosphoinositide3-kinase p110α (PIK3CA)John E. Burke, Olga Perisic, Glenn R. Masson, Oscar Vadas, and Roger L. Williams1. Laboratory of Molecular Biology, Medical
  7. pnas201206839 17424..17429

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/23045692.pdf
    21 Nov 2012: ESCRT-III binding protein MITD1 is involved incytokinesis and has an unanticipated PLD foldthat binds membranesMichael A. Haddersa,1, Monica Agromayorb,2,1, Takayuki Obitaa,3, Olga Perisica, Anna Caballeb, Magdalena Klocb,Meindert H. Lamersa, Roger
  8. doi:10.1016/j.coph.2005.03.002

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15963759.pdf
    12 Nov 2006: Phosphoinositide 3-kinases as drug targets in cancerLen Stephens1, Roger Williams2 and Phillip Hawkins1. The past two years have seen phosphoinositide 3-kinases. (PI3Ks) move from being seen as potential targets for. chemotherapeutics, to one of
  9. PII: S1388-1981(99)00150-X

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10570253.pdf
    20 Apr 2002: Review. Mammalian phosphoinositide-speci¢c phospholipase C. Roger L. Williams Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. Received 1 April 1999 ; received in revised form 17 June 1999 ; accepted 31
  10. A Ternary Metal Binding Site in the C2 Domain ...

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9062102.pdf
    20 Apr 2002: A Ternary Metal Binding Site in the C2 Domain of Phosphoinositide-SpecificPhospholipase C-δ1†,‡. Lars-Oliver Essen,,| Olga Perisic, Denise E. Lynch, Matilda Katan, and Roger L. Williams,. Centre for Protein Engineering, MRC Centre, Hills Road,
  11. Autism

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/ImaginingTheBrain/2012/media/ASC.pptx
    21 Feb 2012: Autism. What is Autism? Autism is a spectrum of neurodevelopmental conditions, characterised by a Triad of Impaiments. Autism is a spectrum condition. This means that the symptoms experienced can vary from very mild, which may never be diagnosed, to
  12. Structural Insights into Endosomal Sorting Complex Required…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15044434.pdf
    24 Sep 2004: Structural Insights into Endosomal Sorting Complex Required forTransport (ESCRT-I) Recognition of Ubiquitinated Proteins. Received for publication, January 5, 2004, and in revised form, March 22, 2004Published, JBC Papers in Press, March 24, 2004,
  13. N402_18f 313..320

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10580505.pdf
    11 Nov 1999: 1999 Macmillan Magazines Ltd. letters to nature. NATURE | VOL 402 | 18 NOVEMBER 1999 | www.nature.com 313. 12. Macleod, K. F. et al. p53-dependent and independent expression of p21 during cell growth,. differentiation, and DNA damage. Genes Dev. 9,
  14. Catalytic Domain of Phosphoinositide-specificPhospholipase C…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9565585.pdf
    20 Apr 2002: Catalytic Domain of Phosphoinositide-specificPhospholipase C (PLC)MUTATIONAL ANALYSIS OF RESIDUES WITHIN THE ACTIVE SITE AND HYDROPHOBIC RIDGE OF PLCd1. (Received for publication, November 20, 1997, and in revised form, February 18, 1998). Moira V.
  15. bc219914979p

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10329700.pdf
    20 Apr 2002: Mapping the Phospholipid-binding Surface and TranslocationDeterminants of the C2 Domain from Cytosolic Phospholipase A2. (Received for publication, November 9, 1998, and in revised form, January 14, 1999). Olga Perisic‡, Hugh F. Paterson, Georgina
  16. Tumour prevention by a single antibody domaintargeting the…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17568777.pdf
    22 Jul 2007: Tumour prevention by a single antibody domaintargeting the interaction of signal transductionproteins with RAS. Tomoyuki Tanaka, Roger L Williamsand Terence H Rabbitts. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK. Many
  17. PII: S1097-2765(01)00372-0

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/11684018.pdf
    20 Apr 2002: Molecular Cell, Vol. 8, 829–839, October, 2001, Copyright 2001 by Cell Press. The Crystal Structure of the PX Domain from p40phoxBound to Phosphatidylinositol 3-Phosphate. Vam7 (Cheever et al., 2001), SNX3 (Xu et al., 2001b),and p40 phox
  18. Phosphoinositide-Specific Phospholipase Cδ1 Activity toward Micellar…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9287165.pdf
    20 Apr 2002: Phosphoinositide-Specific Phospholipase Cδ1 Activity toward Micellar Substrates,Inositol 1,2-Cyclic Phosphate, and Other Water-Soluble Substrates: A Sequential. Mechanism and Allosteric Activation†. Yiqin Wu,‡ Olga Perisic, Roger L. Williams,
  19. doi:10.1016/j.devcel.2004.09.003

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15469844.pdf
    1 Nov 2004: Developmental Cell, Vol. 7, 559–569, October, 2004, Copyright 2004 by Cell Press. ESCRT-II, an Endosome-Associated Complex Requiredfor Protein Sorting: Crystal Structure andInteractions with ESCRT-III and Membranes. Ten of these proteins are
  20. The Structure of a Tunicate C-type Lectin from Polyandrocarpa…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10398588.pdf
    7 Jul 1999: Article No. jmbi.1999.2910 available online at http://www.idealibrary.com on J. Mol. Biol. (1999) 290, 867879. The Structure of a Tunicate C-type Lectin fromPolyandrocarpa misakiensis Complexed withD-Galactose. Se bastien F. Poget1, Glen B. Legge1,
  21. Regulation of lipid binding underlies the activation mechanism of…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/22120714.pdf
    21 Nov 2012: Oncogene 31, 3655 (2012). doi:10.1038/onc.2011.532

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