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AWERB Standing Committee Meeting Minutes - 18th March 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_180320_redacted_0.pdf7 Dec 2022: A letter has been written back to People for the Ethical Treatment of Animals (PETA). -
AWERB Standing Committee Meeting Minutes - 23rd February 2022
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_230222_redacted.pdf7 Dec 2022: Page 3 of 3. Non-Regulated Procedure Request: – The committee reviewed the Non-Regulated procedure request and asked for explanation around how the researcher would recognise/identify individual birds in -
AWERB Operations Committee Reacted Minutes December 2022
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_161222_redacted_0.pdf17 Feb 2023: reminded everyone to include the UBS SC18 mailing list in all reports submitted so the correct people are receiving the information. -
AWERB Operations Committee Redacted Minutes July 2019
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_19.07.19_redacted.pdf11 Jan 2023: has been carrying out more advanced training to “super users”. These will be people in the units who can help with immediate issues. -
AWERB Operations Committee Redacted Minutes October 2019
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_18.10.19_redacted.pdf11 Jan 2023: 2019. distributed some posters for the service tech course. The course is being held on 4th & 5th of December please email with names of people who would like to attend. -
AWERB Standing Committee Meeting Minutes 25th October 2023
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_251023_redacted.pdf28 Nov 2023: people within the group are able to make decisions if the Licence Holder is not available. -
PPL number: | Granted: 06 Aug 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/mice_with_transgenic_immunoglobulin_loci_nts_redacted.pdf20 Aug 2021: owners. As a result, they tend to be given a lower relative dose than people are, to reduce the side effects, but this also means it. ... We can then use this information to help improve drug development for people by giving more accurate information on -
AWERB Sub-Standing Committee Meeting Minutes - 7th February 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_sub-standing_minutes_070220_redacted.pdf7 Dec 2022: b) Amendment: (training) The committee discussed the following:. • Additional text added to reassure the Home Office that licenced people will always be on hand should problems occur. • -
AWERB Standing Committee Meeting Minutes - 28th April 2021
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_280421_redacted.pdf7 Dec 2022: Project Licences (a) Amendment: The committee discussed the following:. • The inclusion of named people as a resource. • -
AWERB Sub-Standing Committee Meeting Minutes - 11th December 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_sub-standing_minutes_111220_redacted.pdf7 Dec 2022: than requested • Clarify in section 2.7, if any of the 70% of animals not useful were shared with other people or. -
AWERB Standing Committee Meeting Minutes - 25th May 2022
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_250522_redacted.pdf7 Dec 2022: The recommendation that the group engages with the Home Office Inspector in response to their comments and keep the Named People in Cambridge involved with this. • -
AWERB Sub-Standing Committee Meeting Minutes - 5th February 2021
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_sub-standing_minutes_050221_redacted.pdf7 Dec 2022: In section 3.7, The committee noted the engagement and working with the NVS and named people in respect to the two mice that died, and to refining the surgical procedures. • -
AWERB Sub-Standing Committee Meeting Minutes - 12th September 2022
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_sub-standing_minutes_120922_redacted.pdf7 Dec 2022: The removal of references to specific people in question 7. -
AWERB Standing Committee Meeting Minutes - 24th March 2021
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_240321_redacted.pdf7 Dec 2022: The removal of specific references from the Non-Technical Summary. • Further clarification around the research into implants and the people they are aimed at in the Non-. -
Make sure you are clear of the University Biomedical ...
https://www.ubs.admin.cam.ac.uk/sites/www.ubs.admin.cam.ac.uk/files/whistle_blowing_process_poster_final.pdf11 Feb 2022: staff. To this end, you can contact any of the following people to discuss your concerns:. -
Axon degeneration and repair (non-technical summary)
https://www.ubs.admin.cam.ac.uk/system/files/public/axon_degeneration_and_repair_non-technical_summary_redacted.pdf30 Apr 2024: Our plan is to publish research papers with new information on which human diseases involve programmed axon death and which specific people are most at risk. ... Individual people in families known to be at risk will also be able to determine their -
r of replacement
https://www.ubs.admin.cam.ac.uk/files/r_of_replacement.pdf18 Aug 2015: Opinion polls in the UK indicate that while many people willsupport some research using animals, they require that the research be forserious medical conditions and causes no unnecessary animal suffering. ... Human cell cultures aregrown under conditions -
QCF Guide for Learners.qxd
https://www.ubs.admin.cam.ac.uk/system/files/public/qcf_guidelearners.pdf26 Sep 2012: This makes learning more flexible as people can complete units at a pace and in a way thatsuits their circumstances and helps providers and employers to create learning programmes that are -
Page 1 of 23 University Biomedical Services University Biomedical ...
https://www.ubs.admin.cam.ac.uk/files/awhandbook_2015.pdf25 Sep 2015: throughout the University of Cambridge. The aim of this induction document is to introduce AWERB Members and Lay People, Scientists,. ... people undertaking Schedule 1 killing and those caring for animals) at the establishment is made known. -
Exploring Bioelectronic Approaches to Nervous System Restoration in…
https://www.ubs.admin.cam.ac.uk/system/files/public/exploring_bioelectronic_approaches_to_nervous_system_restoration_in_large_animals_non-technical_sum_redacted.pdf30 Apr 2024: We're working on a project that studies diseases that affect the entire nervous system, just like they would in people. ... This will help us get reliable data that can be used to develop and improve treatments for nerve diseases in people. -
Working with animals outside the UK, undertaking collaborative work…
https://www.ubs.admin.cam.ac.uk/system/files/public/v1.5_working_with_animals_overseas__0.docx12 Nov 2021: At Cambridge, our research compliance is regulated by ASPA and is monitored by University staff, including the Named People, such as Named Animal Care and Welfare Officers (NACWOs), and Named Veterinary -
Understanding Infection Pathogenesis to Guide Therapies…
https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_infection_pathogenesis_to_guide_therapies_non-technical_summary_redacted.pdf30 Apr 2024: Where possible in our design we blind people to genotype/treatment groups with different people doing infections or analysis. ... We will discuss any advances with the relevant people at our establishment and implement them accordingly. -
1 Responsibility in the use of animals in bioscience ...
https://www.ubs.admin.cam.ac.uk/files/animals_in_research.pdf8 Jan 2015: 3 Humane killing may only be conducted by people adequately trained and listed on the establishment’s register of competent persons. ... People capturing animals should be trained and competent in humane methods of capture, handling and release, and in -
Neurobehavioural Mechanisms Underlying Mood, Anxiety and…
https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_anxiety_and_stress-related_mental_health_disorders_non_redacted.pdf30 Apr 2024: The World Health Organisation estimates that worldwide, 301 million people live with anxiety, 280 million people live with depression, and 326 million people experience post-traumatic stress disorder. ... benefit people living with mental health -
PPL number: | Granted: 31 Jan 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/enteroendocrine_signalling_in_health_and_disease_nts_expires2024_redacted.pdf13 Sep 2021: sugar control and lose weight, whilst decreasing or blocking the signals that make some people sick after surgery, thereby improving their post-surgical quality of live. ... the gut in a similar way used for the treatment of very overweight people. -
Cartilage repair and replacement
https://www.ubs.admin.cam.ac.uk/system/files/public/cartilage_repair_and_replacement_non-technical_summary_redacted.pdf29 Apr 2024: As a result, while it is not possible at this stage to provide a meaningful estimate of the total number of people this technology would benefit it is clear that the -
PPL number: | Granted: 24 May 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_influencing_mammalian_digit_tip_regeneration_redacted.pdf18 Jun 2021: In both mice and people, digit tip regrowth depends on how much of the finger or toe is removed. ... makes us confident that any results we get will also be useful for people. -
Development of Live Bacterial Therapeutics to treat diseases with…
https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_to_treat_diseases_with_intestinal_dysbiosis_non-technica_redacted.pdf29 Apr 2024: It affects about 1 in 400 people in the UK. Crohn's disease affects about 1 in 700 people in the UK. ... In the shorter-term this will involve making new discoveries on the types and behaviour of common gut bacteria found in people and how these interact -
PPL number: | Granted: 04 Apr 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/the_study_of_epithelial_cancer_genes_nts_expires2022_redacted.pdf13 Sep 2021: We will also be studying lung cancer. Nearly 45,000 new cases of lung cancer are diagnosed annually and nearly 35,000 people die from the disease in the UK every -
PPL number: | Granted: 12 Jul 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_pathogen_behaviour_in_relation_to_the_immunity_vaccines_and_antibiotic_treatment_nts_expires2022_redacted.pdf13 Sep 2021: Furthermore, we do not understand how these bacteria spread in the environment and how they infect people. ... Doctors and patients will benefit from this research that will improve the treatment of sick people, especially children and will also reduce -
PPL number: | Granted: 17 Feb 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/roles_for_genomic_instability_in_cancer_and_ageing_redacted.pdf18 Jun 2021: This includes developmental disorders such as progeria, an illness where people show signs of ageing and die early. ... It is estimated that 47 million people live with dementia around the world. -
PPL number: | Granted: 01 Dec 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/radiation_combinations_for_cancer_treatment_nts_redacted.pdf19 Aug 2021: Our research using animals has helped drive advances in cancer treatment that are benefiting people with cancer all over the world today. ... Studies of cancer in mice mimic the complex way tumours grow and spread in people with cancer. -
Interaction between the immune system and tumours (non-technical…
https://www.ubs.admin.cam.ac.uk/system/files/public/interaction_between_the_immune_system_and_tumours_non-technical_summary_redacted.pdf30 Apr 2024: Why is it important to undertake this work? It is now predicted that 1 in 2 people will develop cancer in their lifetime and despite advances with new treatments they do ... We subscribe to the NC3Rs email updates and also receive regular updates from -
Proteotoxicity in development and ageing (non-technical…
https://www.ubs.admin.cam.ac.uk/system/files/public/proteotoxicity_in_development_and_ageing_non-technical_summary_redacted.pdf30 Apr 2024: Downloaded: 9:21pm, 25 Apr 2024 Page 3 of 10. Dementias are the biggest health challenge of our generation; one in three people born today will develop the disease. ... With one million people in the UK predicted to have dementia by 2025 and the current -
Neurobehavioural Mechanisms Underlying Mood, Impulsive and Compulsive …
https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_impulsive_and_compulsive_mental_health_disorders_non-t_redacted.pdf30 Apr 2024: benefit people living with mental health disorders through the development of new treatments. ... In the longer term, understanding the risk factors that predict whether individuals are more vulnerable to developing mental health disorders may allow -
PPL number: | Granted: 28 Jul 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/developing_anti-malarial_transmission_blocking_interventions_nts_redacted.pdf13 Sep 2021: With 3.3 billion people at risk of infection and 229 million people infected with malaria every year, resulting in over 409,000 annual deaths (WHO World Malaria report 2020). ... With billions of people at risk of infection, causing substantial disease -
The development of in vivo expressed biologics as a platform for…
https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_in_vivo_expressed_biologics_as_a_platform_for_novel_therapeutic_agents_non-techn_redacted.pdf30 Apr 2024: Cancer, cardiovascular disease, diabetes and chronic respiratory diseases killed approximately 33.2 million people worldwide in 2019, a 28% increase compared to 2000. ... In the medium term this will allow us to choose the best designs or methods to take -
Discovery and development of treatments for immunological diseases
https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_and_development_of_treatments_for_immunological_diseases_non-technical_summary_redacted.pdf29 Apr 2024: Why is it important to undertake this work? Despite decades of research, millions of people live with serious immune mediated disease such as colitis, arthritis, systemic lupus erythematosus (SLE) and atopic ... dermatitis. For example rheumatoid -
Breeding and maintenance of rodents for drug discovery platform
https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_rodents_for_drug_discovery_platform_non-technical_summary_redacted.pdf29 Apr 2024: Each client is developing drugs which will hopefully contribute to helping people with various diseases with an unmet clinical need. ... For example, we have a large program of work studying haemophilia, a rare (1 in 30,000 people) but life-changing -
Implantation of seeded scaffolds for tissue!organ development…
https://www.ubs.admin.cam.ac.uk/system/files/public/implantation_of_seeded_scaffolds_for_tissueorgan_development_non-technical_summary_redacted.pdf30 Apr 2024: There are currently 6,079 people waiting for a transplant in the UK and many more who are not on the waiting list would benefit from having a diseased or damaged -
Tissue response following synovial joint injury and potential for…
https://www.ubs.admin.cam.ac.uk/system/files/public/tissue_response_following_synovial_joint_injury_and_potential_for_therapies_to_restore_joint_structu_redacted.pdf30 Apr 2024: The most common form of arthritis, osteoarthritis (OA) is believed to affect an estimated 8 million people in the UK, and worldwide this figure rises to 343 million. ... OA is associated with age but younger people are also affected, often impacting on -
PPL number: | Granted: 21 Jan 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/the_long-term_effects_of_developmental_hypoxia_on_cardiac_function_nts_redacted.pdf19 Aug 2021: womb. We hope to identify novel targets for drug intervention to protect people from developing cardiovascular diseases later in life. -
Epigenetic inheritence and the control of developmental and…
https://www.ubs.admin.cam.ac.uk/system/files/public/epigenetic_inheritance_and_the_control_of_developmental_and_physiological_processes_non-technical_s_redacted.pdf30 Apr 2024: For example, Angelman syndrome, an imprinting disorder leading to severe intellectual disability affects 1 in 12,000-1 in 20,000 people worldwide, and Prader-Willi syndrome, another imprinting disorder linked ... to intellectual disability, compulsive -
Understanding the roles of autophagy and related pathways in…
https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_roles_of_autophagy_and_related_pathways_in_proteinopathies_non-technical_summary_redacted.pdf30 Apr 2024: With increased population lifespan, the incidence of people experiencing these devastating disorders will continue to rise. ... Our work has the potential to impact millions of people worldwide both at the social and economic levels. -
Mouse developmental genetics to study neurodevelopment and disease…
https://www.ubs.admin.cam.ac.uk/system/files/public/mouse_developmental_genetics_to_study_neurodevelopment_and_disease_non-technical_summary_redacted.pdf30 Apr 2024: Currently, there are 1.4 million people that are living with acquired brain injuries and 40,000 deaths only from stroke annually in the UK, and an estimated 69 million people -
Genes and environment at the interface of inflammation, immunity and…
https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_environment_at_the_interface_of_inflammation_immunity_and_metabolism_non-technical_summa_redacted.pdf30 Apr 2024: Where possible in our design we blind people to genotype/treatment groups with different people doing infections or analysis. ... We will discuss any advances with the relevant people at our establishment and implement them accordingly. -
Investigating the niche of mucosal parasitic nematodes and their…
https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_niche_of_mucosal_parasitic_nematodes_and_their_interactions_with_their_hosts_non_redacted.pdf30 Apr 2024: Whipworms infect 500 million people worldwide, particularly affecting children 5-15 years of age. ... Hookworms infect 450 million people around the globe, and can cause iron deficiency anaemia, especially in high-risk populations (children and women of -
PPL number: | Granted: 16 Apr 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_of_mental_health_nts_expires2023_redacted.pdf13 Sep 2021: Page 2 of 5. Our research aims to understand how and why mental health disorders occur, and to develop new treatments for people suffering from these disorders. -
PPL number: | Granted: 24 May 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/molecular_mechanisms_of_neuronal_excitation_and_neuroinflammation_nts_expires2023_redacted.pdf13 Sep 2021: Many people suffering from chronic pain are poorly treated by current medications, either due to a lack of efficacy (the drugs do not work), or due to intolerable side effects. -
PPL number: | Granted: 09 Sep 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_for_the_treatment_of_cancer_nts_redacted.pdf13 Sep 2021: Why is it important to undertake this work? Currently around 1 in 2 people will develop cancer in their lifetime. ... In the shorter-term this will involve making new discoveries on the types and behaviour of common gut bacteria found in people and how
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