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30 Apr 2024: Why is it important to undertake this work? It is now predicted that 1 in 2 people will develop cancer in their lifetime and despite advances with new treatments they do ... We subscribe to the NC3Rs email updates and also receive regular updates from

30 Apr 2024: benefit people living with mental health disorders through the development of new treatments. ... In the longer term, understanding the risk factors that predict whether individuals are more vulnerable to developing mental health disorders may allow

30 Apr 2024: Downloaded: 9:21pm, 25 Apr 2024 Page 3 of 10. Dementias are the biggest health challenge of our generation; one in three people born today will develop the disease. ... With one million people in the UK predicted to have dementia by 2025 and the current

30 Apr 2024: There are currently 6,079 people waiting for a transplant in the UK and many more who are not on the waiting list would benefit from having a diseased or damaged

30 Apr 2024: Cancer, cardiovascular disease, diabetes and chronic respiratory diseases killed approximately 33.2 million people worldwide in 2019, a 28% increase compared to 2000. ... In the medium term this will allow us to choose the best designs or methods to take

29 Apr 2024: Why is it important to undertake this work? Despite decades of research, millions of people live with serious immune mediated disease such as colitis, arthritis, systemic lupus erythematosus (SLE) and atopic ... dermatitis. For example rheumatoid

29 Apr 2024: Each client is developing drugs which will hopefully contribute to helping people with various diseases with an unmet clinical need. ... For example, we have a large program of work studying haemophilia, a rare (1 in 30,000 people) but life-changing

30 Apr 2024: The most common form of arthritis, osteoarthritis (OA) is believed to affect an estimated 8 million people in the UK, and worldwide this figure rises to 343 million. ... OA is associated with age but younger people are also affected, often impacting on

30 Apr 2024: For example, Angelman syndrome, an imprinting disorder leading to severe intellectual disability affects 1 in 12,000-1 in 20,000 people worldwide, and Prader-Willi syndrome, another imprinting disorder linked ... to intellectual disability, compulsive

30 Apr 2024: Currently, there are 1.4 million people that are living with acquired brain injuries and 40,000 deaths only from stroke annually in the UK, and an estimated 69 million people

30 Apr 2024: With increased population lifespan, the incidence of people experiencing these devastating disorders will continue to rise. ... Our work has the potential to impact millions of people worldwide both at the social and economic levels.

30 Apr 2024: Where possible in our design we blind people to genotype/treatment groups with different people doing infections or analysis. ... We will discuss any advances with the relevant people at our establishment and implement them accordingly.

30 Apr 2024: Whipworms infect 500 million people worldwide, particularly affecting children 5-15 years of age. ... Hookworms infect 450 million people around the globe, and can cause iron deficiency anaemia, especially in high-risk populations (children and women of

30 Apr 2024: In the UK, the number of people with dementia is estimated to exceed one million in 2025 (National Health Service - Dementia guide). ... memory in disorders such as dementia and dyslexia which significant number of people are suffering from.

29 Apr 2024: Furthermore, to determine whether inhibition of the activities of these proteins will be effective in the treatment of people with cancer. ... Downloaded: 9:12pm, 25 Apr 2024 Page 6 of 11. Some mice can experience weight loss due to the effects of the

30 Apr 2024: Finding treatments for all aspects of patient care therefore is crucial to improve outcomes for people affected. ... All clients that we work with are developing test agents which will hopefully contribute to helping people with various bleeding disorders

30 Apr 2024: However, although many more people now survive, e.g., heart attacks and stroke, the debilitating consequences on quality of life and high risk of a secondary event leads to a huge

29 Apr 2024: treat people after they have contracted a disease. ... Future pandemics are inevitable as the global population expands - our vaccines aim to reduce the risk of such pandemics happening again, by protecting people through vaccination, against viruses of

30 Apr 2024: It also allows several people to work in parallel in different tissues such as bone marrow and blood that need to be handled fresh, thereby maximising the data obtained from single

30 Apr 2024: They can cause significant burden to the patient, their families, and society as a whole; 14% of the social care budget in England is spent on people living with neurological conditions, ... Conditions involving neurodegeneration (when brain cells are