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14 Aug 2023: Plant Synthetic Biology. University of Cambridge, Plant Sciences Part II. Discuss the relative benefits and difficulties of genetically reprogramming metabolism in algae versus plants. Describe recent advances in the assembly of synthetic DNAs. What

14 Aug 2023: Plant Visions 1904-2004. An exhibition of images to celebrate the centenary of the opening of the Plant Sciences laboratories in 1904. Curated by Beverley Glover (website) and Jim Haseloff. Click here to view the exhibit. Download a copy of the

14 Aug 2023: 3D visualisation. Individual cells can be segmented using confocal datasets and rendered in three dimensions. Whole tissues can be reconstructed from the component cells - as shown here for a root meristem within an Arabidopsis embryo. Outer cells

14 Aug 2023: Abstract: Malaria is a global health problem that threatens 300-500 million people and kills more than one million people annually.

14 Aug 2023: Crystals, microbes and plants. Fernán Federici & Jim Haseloff. “What are the roots that clutch, what branches grow. Out of this stony rubbish?”. TS Eliot, The Waste Land. Part of a pioneering new exhibition, ‘April is the Cruellest Month.’

14 Aug 2023: Synthetic Genomics. A series of papers has been published in Science (10th March 2017), which provide a picture of current progress to resynthesise the entire genome of Saccharomyces cerevisiae - the SC2.0 project (). Four of these papers have been

14 Aug 2023: Vanguard Alta Pro 2+ 263AT with GH-100 pistol grip ball & socket head. For high resolution and/or time-lapse work with small plants like liverworts, a camera support is very useful…even essential. The camera support of course needs to be stable,

14 Aug 2023: Mk I Handheld Macroscope (Spring 2017). Original setup for high resolution handheld macrophotography. 1. Panasonic Lumix GX80 camera with 16 megapixel 4/3" sensor, image stabilisation, 4K video, focus bracketing and image stacking. 2. Neewer 10mm

14 Aug 2023: Weatherproof cameras for field documentation. Comparison of Olympus TG-4 and TG-5 cameras for handheld collection of extended focus macrographs. The TG-4 is an extremely robust point-and-shoot camera that can be equipped with an LED illuminator (LG-1

14 Aug 2023: The wild type Aequorea victoria green fluorescent protein mRNA is mis-spliced in Arabidopsis thaliana. GFP sequences were amplified from DNA or mRNA isolated from transgenic Arabidopsis thaliana C24 plantlets. Radiolabelled products were then mapped

14 Aug 2023: GFP background. Aequorea victoria are brightly luminescent jellyfish, with glowing points around the margin of the umbrella. Light arises from yellow tissue masses that each consist of about 6000-7000 photogenic cells. The cytoplasm of these cells

14 Aug 2023: Maturation of green fluorescent protein. The post-translational maturation of GFP to the fluorescent form involves a number of steps. In the first step, the GFP apoprotein presumably must fold into a catalytically active conformation that

14 Aug 2023: Jim Haseloff. email: jh295(at)cam.ac.uk. Haseloff Lab. Department of Plant Sciences. University of Cambridge. Downing Street. Cambridge CB2 3EA. United Kingdom. tel: 44-1223-766546. swb: 44-1223-333900. web: http://haseloff.plantsci.cam.ac.uk.

14 Aug 2023: Manuel Waller, Eftychios Frangedakis, Alan O Marron, Susanna Sauret-Gueto, Jenna Rever, Cyrus Raja Rubenstein Sabbagh, Julian M Hibberd, Jim Haseloff, Karen Renzaglia, Péter Szövényi. Plant Journal, doi: 10.1111/tpj.16161. 2023. Land plants

14 Aug 2023: Research projects in the Haseloff Laboratory. Synthetic Biology is an emerging field that employs engineering principles to construct new genetic systems. The approach is based on the use of well characterised and reusable DNA components, and

14 Aug 2023: Part 1B Cellular & Developmental Biology. Plant Development. Prof. Jim Haseloff, University of Cambridge. Summary:. These four lectures cover some striking features of biological self-organisation and morphogenesis using examples from the model plant

14 Aug 2023: Cambridge-JIC teams in the international Genetically Engineered Machine (iGEM) competition. iGEM is an international undergraduate synthetic biology competition where student teams are given access to DNA parts from the Registry of Standard

14 Aug 2023: iGEM2010 project: E. glowli. The Cambridge iGEM2010 team worked on regeneration systems for bioluminescence and better, brighter light output, different coloured luciferases, instrumentation for quantitation and modelling the feasibility of using

14 Aug 2023: iGEM2009 project: E. chromi. The Cambridge iGEM2009 team created two kits of parts to facilitate the design and construction of biosensors in the the future. These complement genetically engineered bacterial biosensors that enable bacteria to

14 Aug 2023: iGEM2006 project: Self-organisation. Multicellular organisms undergo self-organisation during development. Our aim was to engineer self-organised pattern formation in free swimming bacteria cells by providing them with an artificial system allowing