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PPL number: | Granted: 16 Apr 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_of_mental_health_nts_expires2023_redacted.pdf13 Sep 2021: Page 2 of 5. Our research aims to understand how and why mental health disorders occur, and to develop new treatments for people suffering from these disorders. -
Genes and environment at the interface of inflammation, immunity and…
https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_environment_at_the_interface_of_inflammation_immunity_and_metabolism_non-technical_summa_redacted.pdf30 Apr 2024: Where possible in our design we blind people to genotype/treatment groups with different people doing infections or analysis. ... We will discuss any advances with the relevant people at our establishment and implement them accordingly. -
Investigating the niche of mucosal parasitic nematodes and their…
https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_niche_of_mucosal_parasitic_nematodes_and_their_interactions_with_their_hosts_non_redacted.pdf30 Apr 2024: Whipworms infect 500 million people worldwide, particularly affecting children 5-15 years of age. ... Hookworms infect 450 million people around the globe, and can cause iron deficiency anaemia, especially in high-risk populations (children and women of -
PPL number: | Granted: 24 May 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/molecular_mechanisms_of_neuronal_excitation_and_neuroinflammation_nts_expires2023_redacted.pdf13 Sep 2021: Many people suffering from chronic pain are poorly treated by current medications, either due to a lack of efficacy (the drugs do not work), or due to intolerable side effects. -
PPL number: | Granted: 09 Sep 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_for_the_treatment_of_cancer_nts_redacted.pdf13 Sep 2021: Why is it important to undertake this work? Currently around 1 in 2 people will develop cancer in their lifetime. ... In the shorter-term this will involve making new discoveries on the types and behaviour of common gut bacteria found in people and how -
PPL number: | Granted: 20 Aug 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/training_in_advanced_or_complex_procedures_or_devices_nts_redacted.pdf13 Sep 2021: tumours). How are these learning outcomes important to the people on the course? -
Determining mechanisms of tumour development and relapse following…
https://www.ubs.admin.cam.ac.uk/system/files/public/determining_mechanisms_of_tumour_development_and_relapse_following_treatment_non-technical_summary_redacted.pdf29 Apr 2024: Furthermore, to determine whether inhibition of the activities of these proteins will be effective in the treatment of people with cancer. ... Downloaded: 9:12pm, 25 Apr 2024 Page 6 of 11. Some mice can experience weight loss due to the effects of the -
Neuronal circuit mechanisms underlying cognitive memory judgements…
https://www.ubs.admin.cam.ac.uk/system/files/public/neuronal_circuit_mechanisms_underlying_cognitive_memory_judgements_non-technical_summary_redacted.pdf30 Apr 2024: In the UK, the number of people with dementia is estimated to exceed one million in 2025 (National Health Service - Dementia guide). ... memory in disorders such as dementia and dyslexia which significant number of people are suffering from. -
PPL number: | Granted: 21 Aug 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_role_of_humoral_immunity_in_tissue-specific_immune_responses_in_health_and_disease_redacted.pdf20 Aug 2021: This will help prevent people from getting kidney failure and make kidney transplants last longer, with important benefits; dialysis accounts for 2% of total NHS spending and transplantation restores patient independence -
PPL number: | Granted: 11 Nov 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/mice_with_adaptive_human_immune_systems_and_their_application_for_drug_and_vaccine_discovery_nts_redacted.pdf19 Aug 2021: Therefore, by testing different vaccines in mice with human immune systems we can identify better vaccines that are much more likely to work in people. ... Vaccine candidates that offer improved protection against malaria. A second generation Covid 19
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